Search Results - "PICQ, Madeleine"

The pleiotropic effects of omega-3 docosahexaenoic acid on the hallmarks of Alzheimer's disease by Belkouch, Mounir, Hachem, Mayssa, Elgot, Abdeljalil, Lo Van, Amanda, Picq, Madeleine, Guichardant, Michel, Lagarde, Michel, Bernoud-Hubac, Nathalie

“…Among omega-3 polyunsaturated fatty acids (PUFAs), docosahexaenoic acid (DHA, 22:6n-3) is important for adequate brain development and cognition. DHA is highly…”
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Mechanisms of DHA transport to the brain and potential therapy to neurodegenerative diseases by Lo Van, Amanda, Sakayori, Nobuyuki, Hachem, Mayssa, Belkouch, Mounir, Picq, Madeleine, Lagarde, Michel, Osumi, Noriko, Bernoud-Hubac, Nathalie

“…Docosahexaenoic acid (DHA; 22:6 ω-3) is highly enriched in the brain and is required for proper brain development and function. Its deficiency has been shown…”
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Efficient Docosahexaenoic Acid Uptake by the Brain from a Structured Phospholipid by Hachem, Mayssa, Géloën, Alain, Van, Amanda Lo, Foumaux, Baptiste, Fenart, Laurence, Gosselet, Fabien, Da Silva, Pedro, Breton, Gildas, Lagarde, Michel, Picq, Madeleine, Bernoud-Hubac, Nathalie

“…Docosahexaenoic acid (DHA) is the main essential omega-3 fatty acid in brain tissues required for normal brain development and function. An alteration of brain…”
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Docosahexaenoic Acid (DHA) Bioavailability in Humans after Oral Intake of DHA-Containing Triacylglycerol or the Structured Phospholipid AceDoPC by Hachem, Mayssa, Nacir, Houda, Picq, Madeleine, Belkouch, Mounir, Bernoud-Hubac, Nathalie, Windust, Anthony, Meiller, Laure, Sauvinet, Valerie, Feugier, Nathalie, Lambert-Porcheron, Stephanie, Laville, Martine, Lagarde, Michel

“…AceDoPC is a structured glycerophospholipid that targets the brain with docosahexaenoic acid (DHA) and is neuroprotective in the experimental ischemic stroke…”
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Synthesis and Evaluation of Polyunsaturated Fatty Acid-Phenol Conjugates as Anti-Carbonyl-Stress Lipophenols by Crauste, Céline, Vigor, Claire, Brabet, Philippe, Picq, Madeleine, Lagarde, Michel, Hamel, Christian, Durand, Thierry, Vercauteren, Joseph

“…Carbonyl and oxidative stress play a substantial role in various neurodegenerative diseases such as Alzheimer's Disease, Parkinsonism, and Age‐related Macular…”
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Specific uptake of DHA by the brain from a structured phospholipid, AceDoPC by Bernoud-Hubac, Nathalie, Hachem, Mayssa, Lo Van, Amanda, Picq, Madeleine, Lagarde, Michel

“…Docosahexaenoic acid (DHA; 22:6 ω-3) is highly enriched in the brain and is required for proper brain development and function. Its deficiency has been shown…”
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AceDoPC, a structured phospholipid to target the brain with docosahexaenoic acid by Lagarde, Michel, Hachem, Mayssa, Picq, Madeleine, Guichardant, Michel, Bernoud-Hubac, Nathalie

“…AceDoPCr (R) is a structured phospholipid or acetyl-LysoPC-DHA made to prevent docosahexaenoic acyl migrating from the sn-2 to sn-1 position of the…”
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Brain-targeting form of docosahexaenoic acid for experimental stroke treatment: MRI evaluation and anti-oxidant impact by Chauveau, Fabien, Cho, Tae-Hee, Perez, Magali, Guichardant, Michel, Riou, Adrien, Aguettaz, Pierre, Picq, Madeleine, Lagarde, Michel, Berthezène, Yves, Nighoghossian, Norbert, Wiart, Marlène

“…Epidemiologic studies report cardiovascular protection conferred by omega-3 fatty acids, in particular docosahexaenoic acid (DHA). However, few experimental…”
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Brain targeting with docosahexaenoic acid as a prospective therapy for neurodegenerative diseases and its passage across blood brain barrier by Hachem, Mayssa, Belkouch, Mounir, Lo Van, Amanda, Picq, Madeleine, Bernoud-Hubac, Nathalie, Lagarde, Michel

“…Docosahexaenoic acid (DHA, 22:6n-3) is the main omega-3 polyunsaturated fatty acid in brain tissues necessary for common brain growth and function. DHA can be…”
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Synthesis and Identification of AceDoxyPC, a Protectin-Containing Structured Phospholipid, Using Liquid Chromatography/Mass Spectrometry by Lo Van, Amanda, Fourmaux, Baptiste, Picq, Madeleine, Guichardant, Michel, Lagarde, Michel, Bernoud-Hubac, Nathalie

“…Fatty acids have many health benefits in a great variety of diseases ranging from cardiovascular to cerebral diseases. For instance, docosahexaenoic acid…”
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Targeting the Brain with a Neuroprotective Omega-3 Fatty Acid to Enhance Neurogenesis in Hypoxic Condition in Culture by Lo Van, Amanda, Sakayori, Nobuyuki, Hachem, Mayssa, Belkouch, Mounir, Picq, Madeleine, Fourmaux, Baptiste, Lagarde, Michel, Osumi, Noriko, Bernoud-Hubac, Nathalie

“…Docosahexaenoic acid (DHA, 22:6n-3) is an essential omega-3 polyunsaturated fatty acid (PUFA) that is required for proper brain development and cerebral…”
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Biological properties of a DHA-containing structured phospholipid (AceDoPC) to target the brain by Lagarde, M, Hachem, M, Bernoud-Hubac, N, Picq, M, Véricel, E, Guichardant, M

“…Abstract 1-acetyl,2-docosahexaenoyl-glycerophosphocholine (AceDoPC) has been made to prevent docosahexaenoyl (DHA) to move to the sn-1 position as it rapidly…”
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Selective Inhibition of Rat Heart cAMP Phosphodiesterases by Lipophilic C-Methyl-2-phenyl-4H-1-benzopyran-4-ones (C-Methylflavones) by GAILLARD, Pascale, HAUTEVILLE, Marcelle, PICQ, Madeleine, DUCLOS, Marie-Christine, DUBOIS, Madeleine, PRIGENT, Annie-France

“…A series of eight methoxylated C-methyl-2-phenyl-4H-1-benzopyran-4-ones 3, 6, 10-15 was evaluated as inhibitors of rat heart cytosolic cyclic nucleotide…”
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Pentasubstituted quercetin analogs as selective inhibitors of particulate 3',5'-cyclic-AMP phosphodiesterase from rat brain by Picq, Madeleine, Prigent, Annie F, Nemoz, Georges, Andre, Annie C, Pacheco, Henri

“…Some penta-O-substituted analogues of quercetin were synthesized and tested for the inhibition of cytosolic and particulate rat brain cyclic AMP and cyclic GMP…”
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Synthesis of Photoreactive Phosphatidic Acid Analogues Displaying Activatory Properties on Cyclic AMP-phosphodiesterases. Photoaffinity Labeling of an Isoform of Phosphodiesterase by Picq, Madeleine, Huang, Yan, Lagarde, Michel, Doutheau, Alain, Nemoz, Georges

“…We have previously shown that phosphatidic acid (PA) is a specific activator of some isoforms of type 4 cyclic nucleotide phosphodiesterases (PDE 4) and that…”
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Specific Effects of n-3 Fatty Acids and 8-bromo-cGMP on the Cyclic Nucleotide Phosphodiesterase Activity in Neonatal Rat Cardiac Myocytes by Picq, Madeleine, Dubois, Madeleine, Grynberg, Alain, Lagarde, Michel, Prigent, Annie-France

“…The authors have previously resolved four forms of cyclic nucleotide phosphodiesterase (PDE) in neonatal rat cultured cardiomyocytes by use of high-performance…”
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Regulation of PDE-4 cAMP phosphodiesterases by phosphatidic acid by Grange, M, Picq, M, Prigent, A F, Lagarde, M, Nemoz, G

“…Phosphatidic acid (PA) has been previously shown to activate specifically some of the isoforms of type 4 cylic nucleotide phosphodiesterases (PDE-4) in an…”
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Developmental differences in distribution of cyclic nucleotide phosphodiesterase isoforms in cardiomyocytes and the ventricular tissue from newborn and adult rats by Picq, M, Dubois, M, Grynberg, A, Lagarde, M, Prigent, A F

“…We characterized cyclic nucleotide phosphodiesterase (PDE) activities in neonatal rat cardiomyocytes and in whole ventricle from newborn and adult rats, to…”
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Flavonoid modulation of protein kinase C activation by Picq, M, Dubois, M, Munari-Silem, Y, Prigent, A F, Pacheco, H

“…The flavonoid quercetin exhibited a biphasic effect on calcium and phospholipid-dependent protein kinase (protein kinase C) activity from rat brain and pig…”
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Inhibition of the different phosphodiesterase isoforms of rat heart cytosol by free fatty acids by Dubois, M, Picq, M, Némoz, G, Lagarde, M, Prigent, A F

“…The sensitivity of the various phosphodiesterase (PDE) isoforms present in the cytosolic compartment of rat heart to the main fatty acids of the saturated, n-3…”
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