Search Results - "PICCARDI, Federica"

Thermoresponsive Iron Oxide Nanocubes for an Effective Clinical Translation of Magnetic Hyperthermia and Heat-Mediated Chemotherapy by Mai, Binh T, Balakrishnan, Preethi B, Barthel, Markus J, Piccardi, Federica, Niculaes, Dina, Marinaro, Federica, Fernandes, Soraia, Curcio, Alberto, Kakwere, Hamilton, Autret, Gwennhael, Cingolani, Roberto, Gazeau, Florence, Pellegrino, Teresa

“…The use of magnetic nanoparticles in oncothermia has been investigated for decades, but an effective combination of magnetic nanoparticles and localized…”
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Increased level of extracellular ATP at tumor sites: in vivo imaging with plasma membrane luciferase by Pellegatti, Patrizia, Raffaghello, Lizzia, Bianchi, Giovanna, Piccardi, Federica, Pistoia, Vito, Di Virgilio, Francesco

“…There is growing awareness that tumour cells build up a "self-advantageous" microenvironment that reduces effectiveness of anti-tumour immune response. While…”
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Conformable hierarchically engineered polymeric micromeshes enabling combinatorial therapies in brain tumours by Di Mascolo, Daniele, Palange, Anna Lisa, Primavera, Rosita, Macchi, Francesca, Catelani, Tiziano, Piccardi, Federica, Spanò, Raffaele, Ferreira, Miguel, Marotta, Roberto, Armirotti, Andrea, Gallotti, Alberto L., Galli, Rossella, Wilson, Christy, Grant, Gerald A., Decuzzi, Paolo

“…The poor transport of molecular and nanoscale agents through the blood–brain barrier together with tumour heterogeneity contribute to the dismal prognosis in…”
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Combined in vivo effect of N-acylethanolamine-hydrolyzing acid amidase and glycogen synthase kinase-3β inhibition to treat multiple sclerosis by Sgroi, Stefania, Romeo, Elisa, Albanesi, Ennio, Piccardi, Federica, Catalano, Federico, Debellis, Doriana, Bertozzi, Fabio, Reggiani, Angelo

“…The current pharmacological approaches to multiple sclerosis (MS) target its inflammatory and autoimmune components, but effective treatments to foster…”
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Bone turnover in wild type and pleiotrophin-transgenic mice housed for three months in the International Space Station (ISS) by Tavella, Sara, Ruggiu, Alessandra, Giuliani, Alessandra, Brun, Francesco, Canciani, Barbara, Manescu, Adrian, Marozzi, Katia, Cilli, Michele, Costa, Delfina, Liu, Yi, Piccardi, Federica, Tasso, Roberta, Tromba, Giuliana, Rustichelli, Franco, Cancedda, Ranieri

“…Bone is a complex dynamic tissue undergoing a continuous remodeling process. Gravity is a physical force playing a role in the remodeling and contributing to…”
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Targeting liposomal chemotherapy via both tumor cell-specific and tumor vasculature- specific ligands potentiates therapeutic efficacy by PASTORINO, Fabio, BRIGNOLE, Chiara, RIBATTI, Domenico, CORTI, Angelo, ALLEN, Theresa M, PONZONI, Mirco, DI PAOLO, Daniela, NICO, Bice, PEZZOLO, Annalisa, MARIMPIETRI, Danilo, PAGNAN, Gabriella, PICCARDI, Federica, CILLI, Michele, LONGHI, Renato

“…Neuroblastoma, the most common solid tumor of infancy derived from the sympathetic nervous system, continues to present a formidable clinical challenge…”
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Spherical polymeric nanoconstructs for combined chemotherapeutic and anti-inflammatory therapies by Lee, Aeju, Di Mascolo, Daniele, Francardi, Marco, Piccardi, Federica, Bandiera, Tiziano, Decuzzi, Paolo, PhD

“…Abstract Nanoparticles can simultaneously deliver multiple agents to cancerous lesions enabling de facto combination therapies. Here, spherical polymeric…”
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Imatinib Mesylate Enhances Therapeutic Effects of Gemcitabine in Human Malignant Mesothelioma Xenografts by BERTINO, Pietro, PICCARDI, Federica, PORTA, Camillo, FAVONI, Roberto, CILLI, Michele, MUTTI, Luciano, GAUDINO, Giovanni

“…Purpose: Platelet-derived growth factor receptor β (PDGFRβ), frequently activated in malignant mesothelioma, is a promising cancer therapeutic target. Imatinib…”
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Enhanced Antitumor Efficacy of Clinical-Grade Vasculature-Targeted Liposomal Doxorubicin by PASTORINO, Fabio, DI PAOLO, Daniela, MARIMPIETRI, Danilo, PAGNAN, Gabriella, CILLI, Michele, LEPEKHIN, Eugene A, GARDE, Seema V, LONGHI, Renato, CORTI, Angelo, ALLEN, Theresa M, WU, Jinzi J, PONZONI, Mirco, PICCARDI, Federica, NICO, Beatrice, RIBATTI, Domenico, DAGA, Antonio, BAIO, Gabriella, NEUMAIER, Carlo E, BRIGNOLE, Chiara, LOI, Monica

“…Purpose: In vivo evaluation of good manufacturing practice-grade targeted liposomal doxorubicin (TVT-DOX), bound to a CD13 isoform expressed on the vasculature…”
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Combined Therapeutic Effects of Vinblastine and Rapamycin on Human Neuroblastoma Growth, Apoptosis, and Angiogenesis by MARIMPIETRI, Danilo, BRIGNOLE, Chiara, PERRI, Patrizia, RIBATTI, Domenico, PONZONI, Mirco, NICO, Beatrice, PASTORINO, Fabio, PEZZOLO, Annalisa, PICCARDI, Federica, CILLI, Michele, DI PAOLO, Daniela, PAGNAN, Gabriella, LONGO, Luca

“…Purpose: Vinblastine and rapamycin displayed synergistic inhibition of human neuroblastoma-related angiogenesis. Here, we studied the antitumor activity of…”
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The Combined Therapeutic Effects of Bortezomib and Fenretinide on Neuroblastoma Cells Involve Endoplasmic Reticulum Stress Response by PAGNAN, Gabriella, DI PAOLO, Daniela, CILLI, Michele, NICO, Beatrice, RIBATTI, Domenico, PISTOIA, Vito, PONZONI, Mirco, CAROSIO, Roberta, PASTORINO, Fabio, MARIMPIETRI, Danilo, BRIGNOLE, Chiara, PEZZOLO, Annalisa, LOI, Monica, GALIETTA, Luis J. V, PICCARDI, Federica

“…Purpose: The proteasome inhibitor bortezomib inhibited cell growth and angiogenesis in neuroblastoma. Bortezomib has been shown to induce synergistic activity…”
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Ligand-targeted liposomal therapies of neuroblastoma by Pastorino, Fabio, Marimpietri, Danilo, Brignole, Chiara, Di Paolo, Daniela, Pagnan, Gabriella, Daga, Antonio, Piccardi, Federica, Cilli, Michele, Allen, Theresa M, Ponzoni, Mirco

“…The central problem in cancer chemotherapy is the severe toxic side effects of anticancer drugs on healthy tissues. The use of liposomes as drug delivery…”
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Erratum to Ponassi R, et al. Cell Cycle Volume 7, Issue 20; pp. 3211-24 by Ponassi, Raffaella, Biasotti, Barbara, Tomati, Valeria, Bruno, Silvia, Poggi, Alessandro, Malacarne, Davide, Cimoli, Guido, Salis, Annalisa, Pozzi, Sarah, Miglino, Maurizio, Damonte, Gianluca, Cozzini, Pietro, Spyrakis, Francesca, Campanini, Barbara, Bagnasco, Luca, Castagnino, Nicoletta, Tortolina, Lorenzo, Mumot, Anna, Frassoni, Francesco, Daga, Antonio, Cilli, Michele, Piccardi, Federica, Monfardini, Ilaria, Perugini, Miriam, Zoppoli, Gabriele, D'Arrigo, Cristina, Pesenti, Raffaele, Parodi, Silvio

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Establishment of an orthotopic glioblastoma mouse model for preclinical studies by Iturrioz-Rodríguez, Nerea, Piccardi, Federica, Bertorelli, Rosalia, Ciofani, Gianni

“…Glioblastoma accounts almost 50% of all brain cancers, being the most common and lethal brain tumor in adults. Despite the current standard gold treatment…”
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A novel Bim-BH3-derived Bcl-XL inhibitor: Biochemical characterization, in vitro, in vivo and ex-vivo anti-leukemic activity by Ponassi, Raffaella, Biasotti, Barbara, Tomati, Valeria, Bruno, Silvia, Poggi, Alessandro, Malacarne, Davide, Cimoli, Guido, Salis, Annalisa, Pozzi, Sarah, Miglino, Maurizio, Damonte, Gianluca, Cozzini, Pietro, Spyrakis, Francesca, Campanini, Barbara, Bagnasco, Luca, Castagnino, Nicoletta, Tortolina, Lorenzo, Mumot, Anna, Frassoni, Francesco, Daga, Antonio, Cilli, Michele, Piccardi, Federica, Monfardini, Ilaria, Perugini, Miriam, Zoppoli, Gabriele, DArrigo, Cristina, Pesenti, Raffaele, Parodi, Silvio

“…BH3-only members of the Bcl-2 family exert a fundamental role in apoptosis induction. This work focuses on the development of a novel peptidic molecule based…”
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Restoring neuronal chloride homeostasis with anti-NKCC1 gene therapy rescues cognitive deficits in a mouse model of Down syndrome by Parrini, Martina, Naskar, Shovan, Alberti, Micol, Colombi, Ilaria, Morelli, Giovanni, Rocchi, Anna, Nanni, Marina, Piccardi, Federica, Charles, Severine, Ronzitti, Giuseppe, Mingozzi, Federico, Contestabile, Andrea, Cancedda, Laura

“…A common feature of diverse brain disorders is the alteration of GABA-mediated inhibition because of aberrant, intracellular chloride homeostasis induced by…”
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Boosting nanomedicine performance by conditioning macrophages with methyl palmitate nanoparticles by Palomba, Roberto, di Francesco, Martina, di Francesco, Valentina, Piccardi, Federica, Catelani, Tiziano, Ferreira, Miguel, Palange, Anna Lisa, Decuzzi, Paolo

“…Surface PEGylation, biological camouflage, shape and stiffness modulation of nanoparticles as well as liver blockade and macrophage depletion have all improved…”
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Effect of Bortezomib on Human Neuroblastoma Cell Growth, Apoptosis, and Angiogenesis by Brignole, Chiara, Marimpietri, Danilo, Pastorino, Fabio, Nico, Beatrice, Di Paolo, Daniela, Cioni, Michela, Piccardi, Federica, Cilli, Michele, Pezzolo, Annalisa, Corrias, Maria Valeria, Pistoia, Vito, Ribatti, Domenico, Pagnan, Gabriella, Ponzoni, Mirco

“…Background: Bortezomib is a selective and reversible inhibitor of the 26S proteasome that shows potent antitumor activity in vitro and in vivo against several…”
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Natural agents targeting the α7‐nicotinic‐receptor in NSCLC: A promising prospective in anti‐cancer drug development by Grozio, Alessia, Paleari, Laura, Catassi, Alessia, Servent, Denis, Cilli, Michele, Piccardi, Federica, Paganuzzi, Michela, Cesario, Alfredo, Granone, Pierluigi, Mourier, Gilles, Russo, Patrizia

“…Nicotinic acetylcholine receptors (nAChR) are expressed on normal bronchial epithelial and nonsmall cell lung cancer (NSCLC) cells and are involved in cell…”
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Natural agents targeting the alpha 7-nicotinic-receptor in NSCLC: A promising prospective in anti-cancer drug development by Grozio, Alessia, Paleari, Laura, Catassi, Alessia, Servent, Denis, Cilli, Michele, Piccardi, Federica, Paganuzzi, Michela, Cesario, Alfredo, Granone, Pierluigi, Mourier, Gilles, Russo, Patrizia

“…Nicotinic acetylcholine receptors (nAChR) are expressed on normal bronchial epithelial and nonsmall cell lung cancer (NSCLC) cells and are involved in cell…”
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