Search Results - "PHILLIPS, G. R"

Abnormal tau induces cognitive impairment through two different mechanisms: synaptic dysfunction and neuronal loss by Di, J., Cohen, L. S., Corbo, C. P., Phillips, G. R., El Idrissi, A., Alonso, A. D.

“…The hyperphosphorylated microtubule-associated protein tau is present in several neurodegenerative diseases, although the causal relationship remains elusive…”
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N-cadherin/FGFR promotes metastasis through epithelial-to-mesenchymal transition and stem/progenitor cell-like properties by Qian, X, Anzovino, A, Kim, S, Suyama, K, Yao, J, Hulit, J, Agiostratidou, G, Chandiramani, N, McDaid, H M, Nagi, C, Cohen, H W, Phillips, G R, Norton, L, Hazan, R B

“…N-cadherin and HER2/neu were found to be co-expressed in invasive breast carcinomas. To test the contribution of N-cadherin and HER2 in mammary tumor…”
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N-cadherin regulates mammary tumor cell migration through Akt3 suppression by Chung, S, Yao, J, Suyama, K, Bajaj, S, Qian, X, Loudig, O D, Eugenin, E A, Phillips, G R, Hazan, R B

“…N-cadherin is a cell–cell adhesion molecule that plays a role in breast cancer metastasis. Here, we show that in vivo expression of N-cadherin in the PyMT…”
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Differential Contribution of Amygdala and Hippocampus to Cued and Contextual Fear Conditioning by Phillips, R. G, LeDoux, J. E

“…The contribution of the amygdala and hippocampus to the acquisition of conditioned fear responses to a cue (a tone paired with footshock) and to context…”
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p21CIP1 mediates reciprocal switching between proliferation and invasion during metastasis by Qian, X, Hulit, J, Suyama, K, Eugenin, E A, Belbin, T J, Loudig, O, Smirnova, T, Zhou, Z N, Segall, J, Locker, J, Phillips, G R, Norton, L, Hazan, R B

“…Cell proliferation and invasion are critical for malignant progression, yet how these processes relate to each other and whether they regulate one another…”
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Fat, plain, but not friendless : self-esteem and peer acceptance of obese pre-adolescent girls by PHILLIPS, R. G, HILL, A. J

“…Poor self-esteem is assumed, but not consistently found, in obese children and adolescents. The aims of this study were a detailed analysis of body weight…”
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Lesions of the dorsal hippocampal formation interfere with background but not foreground contextual fear conditioning by Phillips, R G, LeDoux, J E

“…The effects of hippocampal lesions on the conditioning of fear responses (freezing responses) to contextual stimuli (static, continuously present stimuli) were…”
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wingless expression mediates determination of peripheral nervous system elements in late stages of Drosophila wing disc development by PHILLIPS, R. G, WHITTLE, J. R. S

“…We have used conditional wingless genotypes to dissect the role of this gene in late stages of wing disc development. One of these genotypes (wgIL/wg-lacZ) is…”
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Bronchoscopic guidance makes percutaneous tracheostomy a safe, cost-effective, and easy-to-teach procedure by Barba, Carlos A., Angood, Peter B., Kauder, Donald R., Latenser, Barbara, Martin, Kathy, McGonigal, Michael D., Phillips, Gordon R., Rotondo, Michael F., Schwab, C. William

“…Background. We wanted to assess the efficiency of instituting a modified technique of percutaneous tracheostomy (PET) with bronchoscopic guidance. Methods…”
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Exogenous Expression of N-Cadherin in Breast Cancer Cells Induces Cell Migration, Invasion, and Metastasis by Hazan, Rachel B., Phillips, Greg R., Qiao, Rui Fang, Norton, Larry, Aaronson, Stuart A.

“…E- and N-cadherin are calcium-dependent cell adhesion molecules that mediate cell-cell adhesion and also modulate cell migration and tumor invasiveness. The…”
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Gene therapy effectiveness differs for neuronal survival and behavioral performance by PHILLIPS, R. G, MONJE, M. L, GIULI, L. C, MEIER, T. J, YENARI, M. A, KUNIS, D, SAPOLSKY, R. M

“…If neuronal gene therapy is to be clinically useful, it is necessary to demonstrate neuroprotection when the gene is introduced after insult. We now report…”
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The Presynaptic Particle Web: Ultrastructure, Composition, Dissolution, and Reconstitution by Phillips, Greg R, Huang, Jeffrey K, Wang, Yun, Tanaka, Hidekazu, Shapiro, Lawrence, Zhang, Wandong, Shan, Wei-Song, Arndt, Kirsten, Frank, Marcus, Gordon, Ronald E, Gawinowicz, Mary Ann, Zhao, Yingming, Colman, David R

“…We report the purification of a presynaptic “particle web” consisting of ∼50 nm pyramidally shaped particles interconnected by ∼100 nm spaced fibrils. This is…”
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Limitations in the neuroprotective potential of gene therapy with Bcl-2 by Phillips, Russell G., Lawrence, Matthew S., Ho, Dora Y., Sapolsky, Robert M.

“…Considerable attention has focused on the therapeutic transfer of genes with viral vectors into neurons for the purpose of protecting against neurological…”
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Gamma-protocadherins are targeted to subsets of synapses and intracellular organelles in neurons by Phillips, Greg R, Tanaka, Hidekazu, Frank, Marcus, Elste, Alice, Fidler, Lazar, Benson, Deanna L, Colman, David R

“…The clustered protocadherins (Pcdhs) comprise >50 putative synaptic recognition molecules that are related to classical cadherins and highly expressed in the…”
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Molecular modification of N-cadherin in response to synaptic activity by Tanaka, H, Shan, W, Phillips, G R, Arndt, K, Bozdagi, O, Shapiro, L, Huntley, G W, Benson, D L, Colman, D R

“…The relationship between adhesive interactions across the synaptic cleft and synaptic function has remained elusive. At certain CNS synapses, pre- to…”
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Phenocopies induced with antisense RNA identify the wingless gene by Cabrera, C V, Alonso, M C, Johnston, P, Phillips, R G, Lawrence, P A

“…Earlier work suggested that the wingless gene of Drosophila is required for cooperation within discrete groups of cells during development. We show that…”
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Comparison of Ventral Subicular and Hippocampal Neuron Spatial Firing Patterns in Complex and Simplified Environments by Phillips, Russell G, Eichenbaum, Howard

“…Activity from ventral subicular and hippocampal CA1 neurons was recorded in rats exploring a 4-arm radial maze in which the local and distal cues could be…”
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Global analysis of steady-state polarized fluorescence spectra using trilinear curve resolution by Phillips, G.R., Georghiou, S.

“…Global analysis using trilinear curve resolution is described and shown to be a powerful method for the resolution of polarized fluorescence data arrays, in…”
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Barrier precautions in trauma resuscitation: Real-time analysis utilizing videotape review by Digiacomo, J.Christopher, Hoff, William S, Rotondo, Michael F, Martin, Kathleen, Kauder, Donald R, Anderson, Harry L, Phillips, Gordon R, Schwab, C.William

“…Blood-borne pathogens threaten all individuals involved in emergency health care. Despite recommendations by the Centers for Disease Control and the American…”
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Functional Cis-Heterodimers of N- and R-Cadherins by Shan, Wei-Song, Tanaka, Hidekazu, Phillips, Greg R., Arndt, Kirsten, Yoshida, Mika, Colman, David R., Shapiro, Lawrence

“…Classical cadherins form parallel cis-dimers that emanate from a single cell surface. It is thought that the cis-dimeric form is active in cell-cell adhesion,…”
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