Search Results - "PHILIP CHANG"
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AMPA receptors as drug targets in neurological disease - advantages, caveats, and future outlook
Published in The European journal of neuroscience (01-06-2012)“…Most excitatory transmission in the brain is mediated by the AMPA receptor subtype of the ionotropic glutamate receptors. In many neurological diseases,…”
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High-flux reverse osmosis membranes incorporated with hydrophilic additives for brackish water desalination
Published in Desalination (02-01-2013)“…Novel high-flux reverse osmosis membranes with hydrophilic additives were synthesized and characterized under brackish water desalination conditions. Four…”
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Common envelope evolution on a moving mesh
Published in Monthly notices of the Royal Astronomical Society (01-07-2019)“…Abstract We outline the methodology of simulating common envelope evolution (CEE) with the moving-mesh code manga. We extend manga to include multiple…”
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High-flux and fouling-resistant membranes for brackish water desalination
Published in Journal of membrane science (01-01-2013)“…Novel high-flux and fouling-resistant reverse osmosis membrane were synthesized and characterized under brackish water desalination conditions using 2000ppm…”
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THE COSMOLOGICAL IMPACT OF LUMINOUS TeV BLAZARS. I. IMPLICATIONS OF PLASMA INSTABILITIES FOR THE INTERGALACTIC MAGNETIC FIELD AND EXTRAGALACTIC GAMMA-RAY BACKGROUND
Published in The Astrophysical journal (10-06-2012)“…Inverse Compton cascades (ICCs) initiated by energetic gamma rays (E [> ~] 100 GeV) enhance the GeV emission from bright, extragalactic TeV sources. The…”
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Dendritic Polyglycerol Sulfate Inhibits Microglial Activation and Reduces Hippocampal CA1 Dendritic Spine Morphology Deficits
Published in Biomacromolecules (14-09-2015)“…Hyperactivity of microglia and loss of functional circuitry is a common feature of many neurological disorders including those induced or exacerbated by…”
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The effects of protostellar jet feedback on turbulent collapse
Published in Monthly notices of the Royal Astronomical Society (21-03-2018)“…Abstract We present results of hydrodynamic simulations of massive star-forming regions with and without protostellar jets. We show that jets change the…”
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Docosahexaenoic acid (DHA): a modulator of microglia activity and dendritic spine morphology
Published in Journal of neuroinflammation (22-02-2015)“…Recent studies have revealed that excessive activation of microglia and inflammation-mediated neurotoxicity are implicated in the progression of several…”
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A Targeted Approach to Post-Mastectomy Pain and Persistent Pain following Breast Cancer Treatment
Published in Cancers (16-10-2021)“…Persistent pain following treatment for breast cancer is common and often imprecisely labeled as post-mastectomy pain syndrome (PMPS). PMPS is a disorder with…”
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GW170817: a neutron star merger in a mass-transferring triple system
Published in Monthly notices of the Royal Astronomical Society. Letters (01-02-2018)“…Abstract The light curve of GW170817 is surprisingly blue and bright. Assuming that the event is a binary neutron star merger, we argue that blueness and…”
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Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity
Published in Nature communications (27-06-2014)“…One of the most significant challenges in the development of clinically viable delivery systems for RNA interference therapeutics is to understand how…”
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Patient and Provider‐Reported Satisfaction of Cancer Rehabilitation Telemedicine Visits During the COVID‐19 Pandemic
Published in PM & R (01-12-2021)“…Introduction The coronavirus disease 2019 (COVID‐19) pandemic has accelerated the growth of telemedicine services across the United States. In this study, we…”
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Wireless Smartphone ECG Enables Large-Scale Screening in Diverse Populations
Published in Journal of cardiovascular electrophysiology (01-05-2015)“…Twelve‐Lead ECG as a Cardiovascular Screening Tool Background The ubiquitous presence of internet‐connected phones and tablets presents a new opportunity for…”
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Missing Gamma-Ray Halos and the Need for New Physics in the Gamma-Ray Sky
Published in The Astrophysical journal (01-12-2018)“…An intergalactic magnetic field (IGMF) stronger than 3 × 10−13 G would explain the lack of a bright, extended degree-scale, GeV-energy inverse Compton…”
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Prolonged ampakine exposure prunes dendritic spines and increases presynaptic release probability for enhanced long-term potentiation in the hippocampus
Published in The European journal of neuroscience (01-09-2014)“…CX 546, an allosteric positive modulator of α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid‐type ionotropic glutamate receptors (AMPARs), belongs to a…”
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Blocking brain-derived neurotrophic factor inhibits injury-induced hyperexcitability of hippocampal CA3 neurons
Published in The European journal of neuroscience (01-12-2013)“…Brain trauma can disrupt synaptic connections, and this in turn can prompt axons to sprout and form new connections. If these new axonal connections are…”
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Poly(glycoamidoamine) Brushes Formulated Nanomaterials for Systemic siRNA and mRNA Delivery in Vivo
Published in Nano letters (10-02-2016)“…Safe and effective delivery is required for siRNA and mRNA-based therapeutics to reach their potential. Here, we report on the development of…”
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Glial glutamate transport modulates dendritic spine head protrusions in the hippocampus
Published in Glia (01-07-2012)“…Accumulating evidence supports the idea that synapses are tripartite, whereby perisynaptic astrocytes modulate both pre‐ and postsynaptic function. Although…”
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A Christianson syndrome-linked deletion mutation (Δ287ES288) in SLC9A6 impairs hippocampal neuronal plasticity
Published in Neurobiology of disease (01-10-2019)“…Christianson Syndrome is a rare but increasingly diagnosed X-linked intellectual disability disorder that arises from mutations in SLC9A6/NHE6, a pH-regulating…”
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