Search Results - "PHADKE, Anagha P"

A Phase I Study of Telomerase-specific Replication Competent Oncolytic Adenovirus (Telomelysin) for Various Solid Tumors by Nemunaitis, John, Tong, Alex W, Nemunaitis, Michael, Senzer, Neil, Phadke, Anagha P, Bedell, Cynthia, Adams, Ned, Zhang, Yu-An, Maples, Phillip B, Chen, Salina, Pappen, Beena, Burke, James, Ichimaru, Daiju, Urata, Yasuo, Fujiwara, Toshiyoshi

“…A phase I clinical trial was conducted to determine the clinical safety of Telomelysin, a human telomerase reverse transcriptase (hTERT) promoter driven…”
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Antitumor Activity of an Oncolytic Adenoviral-CD40 Ligand (CD154) Transgene Construct in Human Breast Cancer Cells by GOMES, Erica M, RODRIGUES, Margret S, TONG, Alex W, PHADKE, Anagha P, BUTCHER, Lindsay D, STARLING, Cherry, CHEN, Salina, DONGKUN CHANG, HERNANDEZ-ALCOCEBA, Ruben, NEWMAN, Joseph T, STONE, Marvin J

“…Purpose: CD40 ligand (CD40L, CD154) plays a central role in immunoregulation and also directly modulates epithelial cell growth and differentiation. We…”
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Feline Immunodeficiency Virus Infection Is Characterized by B7+CTLA4+ T Cell Apoptosis by Tompkins, Mary B., Bull, Marta E., Dow, Janet L., Ball, Judith M., Collisson, Ellen W., Winslow, Barbara J., Phadke, Anagha P., Vahlenkamp, Thomas W., Tompkins, Wayne A.

“…The B7.1 and B7.2 costimulatory molecules on antigen-presenting cells provide second signals for regulating T cell immune responses via CD28 and cytotoxic T…”
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Hereditary inclusion body myopathy: single patient response to intravenous dosing of GNE gene lipoplex by Nemunaitis, Gregory, Jay, Chris M, Maples, Phillip B, Gahl, William A, Huizing, Marjan, Yardeni, Tal, Tong, Alex W, Phadke, Anagha P, Pappen, Beena O, Bedell, Cynthia, Allen, Henry, Hernandez, Cathy, Templeton, Nancy S, Kuhn, Joseph, Senzer, Neil, Nemunaitis, John

“…Hereditary inclusion body myopathy (HIBM) is an autosomal recessive adult-onset myopathy due to mutations in the GNE (UDP-N-acetylglucosamine…”
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Safety and in vivo Expression of a GNE-Transgene: A Novel Treatment Approach for Hereditary Inclusion Body Myopathy-2 by Phadke, Anagha P., Jay, Chris, Chen, Salina J., Haddock, Courtney, Wang, Zhaohui, Yu, Yang, Nemunaitis, Derek, Nemunaitis, Gregory, Templeton, Nancy S., Senzer, Neil, Maples, Phillip B., Tong, Alex W., Nemunaitis, John

“…Anagha P. Phadke1, Chris Jay1, Salina J. Chen1, Courtney Haddock1, Zhaohui Wang1, Yang Yu1, Derek Nemunaitis1, Gregory Nemunaitis2,4, Nancy S. Templeton3, Neil…”
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The Role of CC Chemokine Receptor 6 in Host Defense in a Model of Invasive Pulmonary Aspergillosis by Phadke, Anagha P, Akangire, Gangaram, Park, Stacy J, Lira, Sergio A, Mehrad, Borna

“…Invasive aspergillosis is a severe fungal infection afflicting immunocompromised patients, particularly patients with neutrophil defects. CCR6, a…”
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In vivo safety and antitumor efficacy of bifunctional small hairpin RNAs specific for the human Stathmin 1 oncoprotein by Phadke, Anagha P, Jay, Chris M, Wang, Zhaohui, Chen, Salina, Liu, Shengnan, Haddock, Courtney, Kumar, Padmasini, Pappen, Beena O, Rao, Donald D, Templeton, Nancy S, Daniels, Egeenee Q, Webb, Craig, Monsma, David, Scott, Stephanie, Dylewski, Dawna, Frieboes, Hermann B, Brunicardi, Francis Charles, Senzer, Neil, Maples, Phillip B, Nemunaitis, John, Tong, Alex W

“…Bifunctional small hairpin RNAs (bi-shRNAs) are functional miRNA/siRNA composites that are optimized for posttranscriptional gene silencing through concurrent…”
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Hereditary inclusion body myopathy: single patient response to GNE gene Lipoplex therapy by Nemunaitis, Gregory, Maples, Phillip B., Jay, Chris, Gahl, William A., Huizing, Marjan, Poling, Justin, Tong, Alex W., Phadke, Anagha P., Pappen, Beena O., Bedell, Cynthia, Templeton, Nancy S., Kuhn, Joseph, Senzer, Neil, Nemunaitis, John

“…Background Hereditary inclusion body myopathy (HIBM) is an autosomal recessive adult onset myopathy. It is characterized by mutations of the GNE…”
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Pathogenesis of a Texas feline immunodeficiency virus isolate: An emerging subtype of clade B by Phadke, Anagha P., de la Concha-Bermejillo, Andres, Wolf, Alice M., Andersen, Philip R., Baladandayuthapani, Veerabhadran, Collisson, Ellen W.

“…We have recently provided evidence that Texas feline immunodeficiency virus (FIV-TX) isolates are an emerging subtype sharing a common ancestry with clade B…”
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B7 +CTLA4 + T cells engage in T–T cell interactions that mediate apoptosis: a model for lentivirus-induced T cell depletion by Vahlenkamp, Thomas W., Bull, Marta E., Dow, Janet L., Collisson, Ellen W., Winslow, Barbara J., Phadke, Anagha P., Tompkins, Wayne A.F., Tompkins, Mary B.

“…Apoptosis in lymph node (LN) T cells of feline immunodeficiency virus (FIV)-infected cats is associated with cells co-expressing B7.1 and B7.2 costimulatory…”
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The role of inducer cells in mediating in vitro suppression of feline immunodeficiency virus replication by Phadke, Anagha P, Choi, In-Soo, Li, Zhongxia, Weaver, Eric, Collisson, Ellen W

“…CD8 + T-cell-mediated suppression of feline immunodeficiency virus (FIV) replication has been described by several groups, although the mechanisms of…”
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Spontaneous T cell apoptosis in feline immunodeficiency virus (FIV)-infected cats is inhibited by IL2 and anti-B7.1 antibodies by Bull, Marta E., Vahlenkamp, Thomas W., Dow, Janet L., Collisson, Ellen W., Winslow, Barbara J., Phadke, Anagha P., Tompkins, Mary B., Tompkins, Wayne A.F.

“…Lymph node (LN) T cells from feline immunodeficiency virus (FIV)-infected cats have an increased expression of B7 co-stimulatory molecules as well as their…”
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Feline Immunodeficiency Virus Infection Is Characterized by$B7^{+}$ $CTL4^{+}$T Cell Apoptosis by Tompkins, Mary B., Bull, Marta E., Dow, Janet L., Ball, Judith M., Collisson, Ellen W., Winslow, Barbara J., Phadke, Anagha P., Vahlenkamp, Thomas W., Tompkins, Wayne A.

“…The B7.1 and B7.2 costimulatory molecules on antigen-presenting cells provide second signals for regulating T cell immune responses via CD28 and cytotoxic T…”
Get full text