Search Results - "PFAENDER, Stefanie"

Cellular Zinc Homeostasis Contributes to Neuronal Differentiation in Human Induced Pluripotent Stem Cells by Grabrucker, Andreas M., Boeckers, Tobias M., Linta, Leonhard, Achberger, Kevin, Putz, Stefan, Lutz, Anne-Kathrin, Föhr, Karl, Pfaender, Stefanie, Liebau, Stefan

“…Disturbances in neuronal differentiation and function are an underlying factor of many brain disorders. Zinc homeostasis and signaling are important mediators…”
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Application of Polymeric Nanoparticles for CNS Targeted Zinc Delivery In Vivo by Chhabra, Resham, Ruozi, Barbara, Vilella, Antonietta, Belletti, Daniela, Mangus, Katharina, Pfaender, Stefanie, Sarowar, Tasnuva, Boeckers, Tobias Maria, Zoli, Michele, Forni, Flavio, Vandelli, Maria Angela, Tosi, Giovanni, Grabrucker, Andreas Martin

“…A dyshomeostasis of zinc ions has been reported for many psychiatric and neurodegenerative disorders including schizophrenia, attention deficit hyperactivity…”
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Zinc deficiency and low enterocyte zinc transporter expression in human patients with autism related mutations in SHANK3 by Pfaender, Stefanie, Sauer, Ann Katrin, Hagmeyer, Simone, Mangus, Katharina, Linta, Leonhard, Liebau, Stefan, Bockmann, Juergen, Huguet, Guillaume, Bourgeron, Thomas, Boeckers, Tobias M., Grabrucker, Andreas M.

“…Phelan McDermid Syndrome (PMDS) is a genetic disorder characterized by features of Autism spectrum disorders. Similar to reports of Zn deficiency in autistic…”
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Characterization of biometal profiles in neurological disorders by Pfaender, Stefanie, Grabrucker, Andreas M

“…Many neurodegenerative and neuropsychiatric disorders have been reported to coincide with the dysregulation of metal ions in the body and central nervous…”
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Characterization of zinc amino acid complexes for zinc delivery in vitro using Caco-2 cells and enterocytes from hiPSC by Sauer, Ann Katrin, Pfaender, Stefanie, Hagmeyer, Simone, Tarana, Laura, Mattes, Ann-Kathrin, Briel, Franziska, Küry, Sébastien, Boeckers, Tobias M., Grabrucker, Andreas M.

“…Zn is essential for growth and development. The bioavailability of Zn is affected by several factors such as other food components. It is therefore of…”
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Zinc deficiency dysregulates the synaptic ProSAP/Shank scaffold and might contribute to autism spectrum disorders by GRABRUCKER, Stefanie, JANNETTI, Linda, KREUTZ, Michael R, EHRET, Günter, BOECKERS, Tobias M, GRABRUCKER, Andreas M, ECKERT, Matti, GAUB, Simone, CHHABRA, Resham, PFAENDER, Stefanie, MANGUS, Katharina, PARAMESHWAR PASHAM REDDY, RANKOVIC, Vladan, SCHMEISSER, Michael J

“…Proteins of the ProSAP/Shank family act as major organizing scaffolding elements within the postsynaptic density of excitatory synapses. Deletions, mutations…”
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Autism-associated SHANK3 mutations impair maturation of neuromuscular junctions and striated muscles by Lutz, Anne-Kathrin, Pfaender, Stefanie, Incearap, Berra, Ioannidis, Valentin, Ottonelli, Ilaria, Föhr, Karl J, Cammerer, Judith, Zoller, Marvin, Higelin, Julia, Giona, Federica, Stetter, Maximilian, Stoecker, Nicole, Alami, Najwa Ouali, Schön, Michael, Orth, Michael, Liebau, Stefan, Barbi, Gotthold, Grabrucker, Andreas M, Delorme, Richard, Fauler, Michael, Mayer, Benjamin, Jesse, Sarah, Roselli, Francesco, Ludolph, Albert C, Bourgeron, Thomas, Verpelli, Chiara, Demestre, Maria, Boeckers, Tobias M

“…Heterozygous mutations of the gene encoding the postsynaptic protein SHANK3 are associated with syndromic forms of autism spectrum disorders (ASDs). One of the…”
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Characterization of biometal profiles in neurological disordersElectronic supplementary information (ESI) available: See DOI: 10.1039/c4mt00008k by Pfaender, Stefanie, Grabrucker, Andreas M

“…Many neurodegenerative and neuropsychiatric disorders have been reported to coincide with the dysregulation of metal ions in the body and central nervous…”
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Loss of COMMD1 and copper overload disrupt zinc homeostasis and influence an autism-associated pathway at glutamatergic synapses by Baecker, Tanja, Mangus, Katharina, Pfaender, Stefanie, Chhabra, Resham, Boeckers, Tobias M., Grabrucker, Andreas M.

“…Recent studies suggest that synaptic pathology in autism spectrum disorder (ASD) might be caused by the disruption of a signaling pathway at excitatory…”
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Abstract 2749: iPSC-derived natural killer cells as the front-runner program of the EVO cells Oncology platform: From inception to translational validation using patient samples by Esquerré, Michael, Holtzinger, Audrey, Pichery, Mélanie, Pfaender, Stefanie, Yumlu, Saniye, Richter, Mandy, Betous, Delphine, Bombarde, Oriane, Gador, Mylène, Sailer, Nadja, Paillasse, Michael, Ysebaert, Loïc, Despas, Fabien, Austen, Matthias, Scheel, Andreas, Dangl, Markus

“…Cancer immunotherapy has transformed the oncology landscape and shown promising therapeutic results in the clinic but it is also clearly facing multiple…”
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Abstract 3203: EVO cells Oncology: Tailored genetic engineering of iPSC-derived immune effector cells and combination with the right biologic therapeutics result in optimal killing of primary tumor cells from patients by Esquerré, Michael, Holtzinger, Audrey, Wagner, Nadja, Braun, Monika, Pichery, Mélanie, Pfaender, Stefanie, Sontag, Stephanie, Haake, Kathrin, Mirenda, Michela, Paillasse, Michael, Grandolfo, Davide, Beuraud, Chloé, Richter, Mandy, Hublitz, Philip, Bousquet, Julien, Fabre, Marion, Gador, Mylène, Sommermeyer, Daniel, Schneider, Tanja, Bombarde, Oriane, Esquerré, Camille, Ysebaert, Loic, Despas, Fabien, Austen, Matthias, Scheel, Andreas, Dangl, Markus

“…Current autologous cell therapies, with blockbuster products on the market, have been leading for a decade to unprecedented clinical successes in patients with…”
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