Search Results - "PEYROLLIER, Karine"

Hyaluronan-CD44 Interaction Activates Stem Cell Marker Nanog, Stat-3-mediated MDR1 Gene Expression, and Ankyrin-regulated Multidrug Efflux in Breast and Ovarian Tumor Cells by Bourguignon, Lilly Y.W., Peyrollier, Karine, Xia, Weiliang, Gilad, Eli

“…Hyaluronan (HA) is a major glycosaminoglycan in the extracellular matrix whose expression is tightly linked to multidrug resistance and tumor progression. In…”
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Rho GTPases and cancer by Li, Hui, Peyrollier, Karine, Kilic, Gülcan, Brakebusch, Cord

“…Rho GTPases are a family of small GTPases, which play an important role in the regulation of the actin cytoskeleton. Not surprisingly, Rho GTPases are crucial…”
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Heregulin-mediated ErbB2-ERK Signaling Activates Hyaluronan Synthases Leading to CD44-dependent Ovarian Tumor Cell Growth and Migration by Bourguignon, Lilly Y.W., Gilad, Eli, Peyrollier, Karine

“…Heregulin (HRG)-induced cell responses are mediated by the ErbB family of tyrosine kinase receptors. In this study we have investigated HRG activation of…”
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RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes by Jackson, Ben, Peyrollier, Karine, Pedersen, Esben, Basse, Astrid, Karlsson, Richard, Wang, Zhipeng, Lefever, Tine, Ochsenbein, Alexandra M, Schmidt, Gudula, Aktories, Klaus, Stanley, Alanna, Quondamatteo, Fabio, Ladwein, Markus, Rottner, Klemens, van Hengel, Jolanda, Brakebusch, Cord

“…RhoA is a small guanosine-5'-triphosphatase (GTPase) suggested to be essential for cytokinesis, stress fiber formation, and epithelial cell-cell contacts. In…”
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Matrix Metalloproteinase-9 Facilitates Glial Scar Formation in the Injured Spinal Cord by Hsu, Jung-Yu C, Bourguignon, Lilly Y. W, Adams, Christen M, Peyrollier, Karine, Zhang, Haoqian, Fandel, Thomas, Cun, Christine L, Werb, Zena, Noble-Haeusslein, Linda J

“…In the injured spinal cord, a glial scar forms and becomes a major obstacle to axonal regeneration. Formation of the glial scar involves migration of…”
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Hyaluronan-CD44 Interaction with IQGAP1 Promotes Cdc42 and ERK Signaling, Leading to Actin Binding, Elk-1/Estrogen Receptor Transcriptional Activation, and Ovarian Cancer Progression by Bourguignon, Lilly Y.W., Gilad, Eli, Rothman, Kori, Peyrollier, Karine

“…In this study, we have examined the interaction of hyaluronan (HA)-CD44 with IQGAP1 (one of the binding partners for the Rho GTPase Cdc42) in SK-OV-3.ipl human…”
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RAC1 in keratinocytes regulates crosstalk to immune cells by Arp2/3-dependent control of STAT1 by Pedersen, Esben, Wang, Zhipeng, Stanley, Alanna, Peyrollier, Karine, Rösner, Lennart M, Werfel, Thomas, Quondamatteo, Fabio, Brakebusch, Cord

“…Crosstalk between keratinocytes and immune cells is crucial for the immunological barrier function of the skin, and aberrant crosstalk contributes to…”
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L-leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the L-leucine-induced up-regulation of system A amino acid transport by Peyrollier, K, Hajduch, E, Blair, A S, Hyde, R, Hundal, H S

“…Amino acid availability is known to regulate diverse cell processes including the activation of p70 S6 kinase, initiation factors involved in mRNA translation,…”
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Insulin Promotes the Cell Surface Recruitment of the SAT2/ATA2 System A Amino Acid Transporter from an Endosomal Compartment in Skeletal Muscle Cells by Hyde, Russell, Peyrollier, Karine, Hundal, Harinder S.

“…SAT1–3 comprise members of the recently cloned family of System A transporters that mediate the sodium-coupled uptake of short chain neutral amino acids, and…”
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Human α-endosulfine, a possible regulator of sulfonylurea-sensitive KATP channel: Molecular cloning, expression and biological properties by Heron, L, Virsolvy, A, Peyrollier, K, Gribble, F M, Le Cam, A, Ashcroft, F M, Bataille, D

“…Sulfonylureas are a class of drugs commonly used in the management of non-insulin-dependent diabetes mellitus. Their therapeutic action results primarily from…”
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l-Leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the l-leucine-induced up-regulation of System A amino acid transport by PEYROLLIER, Karine, HAJDUCH, Eric, BLAIR, Anne S., HYDE, Russell, HUNDAL, Harinder S.

“…Amino acid availability is known to regulate diverse cell processes including the activation of p70 S6 kinase, initiation factors involved in mRNA translation,…”
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A role for the actin cytoskeleton in the hormonal and growth-factor-mediated activation of protein kinase B by PEYROLLIER, Karine, HAJDUCH, Eric, GRAY, Alexander, LITHERLAND, Gary J., PRESCOTT, Alan R., LESLIE, Nick R., HUNDAL, Harinder S.

“…We show here that cytochalasin D-induced depolymerization of actin filaments markedly reduces the stimulus-dependent activation of protein kinase B (PKB) in…”
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RhoA controls retinoid signaling by ROCK dependent regulation of retinol metabolism by García-Mariscal, Alberto, Peyrollier, Karine, Basse, Astrid, Pedersen, Esben, Rühl, Ralph, van Hengel, Jolanda, Brakebusch, Cord

“…The ubiquitously expressed small GTPase RhoA is essential for embryonic development and mutated in different cancers. Functionally, it is well described as a…”
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Hyaluronan-CD44 Interaction with Neural Wiskott-Aldrich Syndrome Protein (N-WASP) Promotes Actin Polymerization and ErbB2 Activation Leading to β-Catenin Nuclear Translocation, Transcriptional Up-regulation, and Cell Migration in Ovarian Tumor Cells by Bourguignon, Lilly Y.W., Peyrollier, Karine, Gilad, Eli, Brightman, Amy

“…In this study we have investigated the interaction of hyaluronan (HA) and CD44 with the neuronal Wiskott-Aldrich syndrome protein (N-WASP) in regulating actin…”
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Hyaluronan‐CD44 interaction stimulates Rac1 signaling and PKNγ kinase activation leading to cytoskeleton function and cell migration in astrocytes by Bourguignon, Lilly Y. W., Gilad, Eli, Peyrollier, Karine, Brightman, Amy, Swanson, Raymond A.

“…Both hyaluronan [HA, the major glycosaminoglycans in the extracellular matrix (ECM)] and CD44 (a primary HA receptor) are associated with astrocyte activation…”
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Hyaluronan-CD44 Interaction with Neural Wiskott-Aldrich Syndrome Protein (N-WASP) Promotes Actin Polymerization and ErbB2 Activation Leading to β-Catenin Nuclear Translocation, Transcriptional Up-regulation, and Cell Migration in Ovarian Tumor Cells by Lilly Y. W. Bourguignon, Karine Peyrollier, Eli Gilad, Amy Brightman

“…In this study we have investigated the interaction of hyaluronan (HA) and CD44 with the neuronal Wiskott-Aldrich syndrome protein (N-WASP) in regulating actin…”
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Hyaluronan-CD44 interaction stimulates Rac1 signaling and PKN[gamma] kinase activation leading to cytoskeleton function and cell migration in astrocytes by Bourguignon, Lilly Y W, Gilad, Eli, Peyrollier, Karine, Brightman, Amy, Swanson, Raymond A

“…Both hyaluronan [HA, the major glycosaminoglycans in the extracellular matrix (ECM)] and CD44 (a primary HA receptor) are associated with astrocyte activation…”
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Regulation of membrane-type 1 matrix metalloproteinase activity by vacuolar H+-ATPases by Maquoi, Erik, Peyrollier, Karine, Noël, Agnès, Foidart, Jean-Michel, Frankenne, Francis

“…Membrane-type 1 matrix metalloproteinase (MT1-MMP) is a key enzyme in normal development and malignant processes. The regulation of MT1-MMP activity on the…”
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Mice without uPA, tPA, or Plasminogen Genes Are Resistant to Experimental Choroidal Neovascularization by Rakic, Jean-Marie, Lambert, Vincent, Munaut, Carine, Bajou, Khalid, Peyrollier, Karine, Alvarez-Gonzalez, Marie-Luz, Carmeliet, Peter, Foidart, Jean-Michel, Noel, Agnes

“…To evaluate the presence and potential involvement of members of the plasminogen/plasminogen activator (Plg/PA) system in the exudative form of age-related…”
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Rho GTPase knockout induction in primary keratinocytes from adult mice by Pedersen, Esben, Basse, Astrid, Lefever, Tine, Peyrollier, Karine, Brakebusch, Cord

“…Primary keratinocytes are an important tool to investigate the molecular mechanism underlying the skin phenotype of mice with null mutations in Rho GTPase…”
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