Search Results - "PEUCHMAUR, Michel"

Whole-Exome Sequencing of Cell-Free DNA Reveals Temporo-spatial Heterogeneity and Identifies Treatment-Resistant Clones in Neuroblastoma by Chicard, Mathieu, Colmet-Daage, Leo, Clement, Nathalie, Danzon, Adrien, Bohec, Mylène, Bernard, Virginie, Baulande, Sylvain, Bellini, Angela, Deveau, Paul, Pierron, Gaëlle, Lapouble, Eve, Janoueix-Lerosey, Isabelle, Peuchmaur, Michel, Corradini, Nadège, Defachelles, Anne Sophie, Valteau-Couanet, Dominique, Michon, Jean, Combaret, Valérie, Delattre, Olivier, Schleiermacher, Gudrun

“…Neuroblastoma displays important clinical and genetic heterogeneity, with emergence of new mutations at tumor progression. To study clonal evolution during…”
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Ontogeny of human mucosal-associated invariant T cells and related T cell subsets by Ben Youssef, Ghada, Tourret, Marie, Salou, Marion, Ghazarian, Liana, Houdouin, Véronique, Mondot, Stanislas, Mburu, Yvonne, Lambert, Marion, Azarnoush, Saba, Diana, Jean-Sébastien, Virlouvet, Anne-Laure, Peuchmaur, Michel, Schmitz, Thomas, Dalle, Jean-Hugues, Lantz, Olivier, Biran, Valérie, Caillat-Zucman, Sophie

“…Mucosal-associated invariant T (MAIT) cells are semi-invariant Vα7.2 CD161 CD4 T cells that recognize microbial riboflavin precursor derivatives such as…”
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Emergence of new ALK mutations at relapse of neuroblastoma by Schleiermacher, Gudrun, Javanmardi, Niloufar, Bernard, Virginie, Leroy, Quentin, Cappo, Julie, Rio Frio, Thomas, Pierron, Gaelle, Lapouble, Eve, Combaret, Valérie, Speleman, Frank, de Wilde, Bram, Djos, Anna, Ora, Ingrid, Hedborg, Fredrik, Träger, Catarina, Holmqvist, Britt-Marie, Abrahamsson, Jonas, Peuchmaur, Michel, Michon, Jean, Janoueix-Lerosey, Isabelle, Kogner, Per, Delattre, Olivier, Martinsson, Tommy

“…In neuroblastoma, the ALK receptor tyrosine kinase is activated by point mutations. We investigated the potential role of ALK mutations in neuroblastoma clonal…”
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Activated ALK signals through the ERK–ETV5–RET pathway to drive neuroblastoma oncogenesis by Lopez-Delisle, Lucille, Pierre-Eugène, Cécile, Louis-Brennetot, Caroline, Surdez, Didier, Raynal, Virginie, Baulande, Sylvain, Boeva, Valentina, Grossetête-Lalami, Sandrine, Combaret, Valérie, Peuchmaur, Michel, Delattre, Olivier, Janoueix-Lerosey, Isabelle

“…Activating mutations of the ALK receptor occur in a subset of neuroblastoma tumors. We previously demonstrated that Alk mutations cooperate with MYCN…”
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Genomic Copy Number Profiling Using Circulating Free Tumor DNA Highlights Heterogeneity in Neuroblastoma by Chicard, Mathieu, Boyault, Sandrine, Colmet Daage, Leo, Richer, Wilfrid, Gentien, David, Pierron, Gaelle, Lapouble, Eve, Bellini, Angela, Clement, Nathalie, Iacono, Isabelle, Bréjon, Stéphanie, Carrere, Marjorie, Reyes, Cécile, Hocking, Toby, Bernard, Virginie, Peuchmaur, Michel, Corradini, Nadège, Faure-Conter, Cécile, Coze, Carole, Plantaz, Dominique, Defachelles, Anne Sophie, Thebaud, Estelle, Gambart, Marion, Millot, Frédéric, Valteau-Couanet, Dominique, Michon, Jean, Puisieux, Alain, Delattre, Olivier, Combaret, Valérie, Schleiermacher, Gudrun

“…The tumor genomic copy number profile is of prognostic significance in neuroblastoma patients. We have studied the genomic copy number profile of cell-free DNA…”
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Clinical and histological differences between adults and children in new onset IgA nephropathy by Cambier, Alexandra, Rabant, Marion, El Karoui, Khalil, Peuchmaur, Michel, Servais, Aude, Hertig, Alexandre, Deschenes, Georges, Salomon, Remi, Hogan, Julien, Robert, Thomas

“…Background Previous reports suggest initial presentation of IgA nephropathy (IgAN) in children is different from adults. No systematic comparison of clinical,…”
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Overall Genomic Pattern Is a Predictor of Outcome in Neuroblastoma by JANOUEIX-LEROSEY, Isabelle, SCHLEIERMACHER, Gudrun, PLANTAZ, Dominique, RUBIE, Hervé, VALTEAU-COUANET, Dominique, THOMAS, Caroline, COMBARET, Valérie, ROUSSEAU, Raphaël, EGGERT, Angelika, MICHON, Jean, SPELEMAN, Frank, DELATTRE, Olivier, MICHELS, Evi, MOSSERI, Veronique, RIBEIRO, Agnès, LEQUIN, Delphine, VERMEULEN, Joëlle, COUTURIER, Jérome, PEUCHMAUR, Michel, VALENT, Alexander

“…For a comprehensive overview of the genetic alterations of neuroblastoma, their association and clinical significance, we conducted a whole-genome DNA copy…”
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Radiogenomics of neuroblastomas: Relationships between imaging phenotypes, tumor genomic profile and survival by Brisse, Hervé J, Blanc, Thomas, Schleiermacher, Gudrun, Mosseri, Véronique, Philippe-Chomette, Pascale, Janoueix-Lerosey, Isabelle, Pierron, Gaelle, Lapouble, Eve, Peuchmaur, Michel, Fréneaux, Paul, Galmiche, Louise, Algret, Nathalie, Peycelon, Matthieu, Michon, Jean, Delattre, Olivier, Sarnacki, Sabine

“…This study investigated relationships between neuroblastomas (NBs) imaging phenotypes, tumor genomic profile and patient outcome. This IRB-approved…”
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Small bowel stenosis: a manifestation of chronic graft-versus-host disease in children? by Tordjman, Mickael, Ouachee, Marie, Bonnard, Arnaud, Tilea, Bogdana, Yakouben, Karima, Viala, Jerome, Peuchmaur, Michel, Berrebi, Dominique

“…Digestive graft-versus-host disease (GVHD) is a frequent complication after bone marrow transplantation, but small bowel obstruction is an extremely rare…”
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Neonatal cancer by Orbach, Daniel, MD, Sarnacki, Sabine, Prof, Brisse, Hervé J, MD, Gauthier-Villars, Marion, MD, Jarreau, Pierre-Henri, Prof, Tsatsaris, Vassilis, Prof, Baruchel, André, Prof, Zerah, Michel, Prof, Seigneur, Etienne, MD, Peuchmaur, Michel, Prof, Doz, François, Prof

“…Summary Neonatal cancer is rare and comprises a heterogeneous group of neoplasms with substantial histological diversity. Almost all types of paediatric cancer…”
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Calretinin immunohistochemistry: a simple and efficient tool to diagnose Hirschsprung disease by Guinard-Samuel, Vincent, Bonnard, Arnaud, De Lagausie, Pascal, Philippe-Chomette, Pascale, Alberti, Corine, El Ghoneimi, Alaa, Peuchmaur, Michel, Berrebi-Binczak, Dominique

“…Diagnosis of Hirschsprung disease (HD) is quite entirely based on the histopathological analysis of suction rectal biopsies. This hematoxylin and eosin…”
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CCR1 inhibition ameliorates the progression of lupus nephritis in NZB/W mice by Bignon, Alexandre, Gaudin, Françoise, Hémon, Patrice, Tharinger, Hugo, Mayol, Katia, Walzer, Thierry, Loetscher, Pius, Peuchmaur, Michel, Berrebi, Dominique, Balabanian, Karl

“…Systemic lupus erythematosus is a chronic inflammatory autoimmune disease, the development of which is characterized by a progressive loss of renal function…”
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Immunosuppressive Treatment in Children With IgA Nephropathy and the Clinical Value of Podocytopathic Features by Cambier, Alexandra, Rabant, Marion, Peuchmaur, Michel, Hertig, Alexandre, Deschenes, Georges, Couchoud, Cecile, Kolko, Anne, Salomon, Remi, Hogan, Julien, Robert, Thomas

“…There is a need for treatment guidelines and prognostic factor identification in children with primary IgA nephropathy. We analyzed the causative effect of…”
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LOCALIZATION AND mRNA EXPRESSION OF CYP3A AND P-GLYCOPROTEIN IN HUMAN DUODENUM AS A FUNCTION OF AGE by FAKHOURY, May, LITALIEN, Catherine, MEDARD, Yves, CAVE, Helene, EZZAHIR, Nadia, PEUCHMAUR, Michel, JACQZ-AIGRAIN, Evelyne

“…Cytochromes P450 3A (CYP3A) and P-glycoprotein (P-gp) are mainly located in enterocytes and hepatocytes. The CYP3A/P-gp system contributes to the first-pass…”
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A variant of ASIC2 mediates sodium retention in nephrotic syndrome by Fila, Marc, Sassi, Ali, Brideau, Gaëlle, Cheval, Lydie, Morla, Luciana, Houillier, Pascal, Walter, Christine, Gennaoui, Michel, Collignon, Laure, Keck, Mathilde, Planelles, Gabrielle, Bakouh, Naziha, Peuchmaur, Michel, Deschênes, Georges, Anegon, Ignacio, Remy, Séverine, Vogt, Bruno, Crambert, Gilles, Doucet, Alain

“…Idiopathic nephrotic syndrome (INS) is characterized by proteinuria and renal sodium retention leading to edema. This sodium retention is usually attributed to…”
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Inflammatory alterations in mesenteric adipose tissue in Crohn's disease by Desreumaux ,‡, Pierre, Ernst §, Olivier, Geboes ∥, Karel, Gambiez ¶, Luc, Berrebi #, Dominique, Müller-Alouf ‡, Heide, Hafraoui, Samira, Emilie, Dominique, Ectors ∥, Nadine, Peuchmaur #, Michel, Cortot, Antoine, Capron ‡, Monique, Auwerx ‡‡, Johan, Colombel, Jean-Frédéric

“…Background & Aims: Abnormalities of fat in the mesentery including adipose tissue hypertrophy and fat wrapping have been long recognized on surgical specimens…”
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Transformation of a low-grade follicular lymphoma into a composite lymphoma combining a high-grade B-cell lymphoma and a lymphoblastic neoplasm expressing Terminal deoxynucleotidyl Transferase: a case report by Bouroumeau, Antonin, Kaphan, Eleonore, Legrand, Clémentine, Raskovalova, Tatiana, Szymanski, Gautier, Vettier, Claire, Lefebvre, Christine, Jacob, Marie-Christine, McLeer, Anne, Peuchmaur, Michel, Gressin, Rémy, Sartelet, Hervé

“…High-grade B-cell lymphoma with rearrangements of MYC and BCL2 and/or BCL6 is an aggressive mature B-cell neoplasm, whereas B-lymphoblastic lymphoma is…”
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Synthesis of glucocorticoid-induced leucine zipper (GILZ) by macrophages: an anti-inflammatory and immunosuppressive mechanism shared by glucocorticoids and IL-10 by Berrebi, Dominique, Bruscoli, Stefano, Cohen, Nicolas, Foussat, Arnaud, Migliorati, Graziella, Bouchet-Delbos, Laurence, Maillot, Marie-Christine, Portier, Alain, Couderc, Jacques, Galanaud, Pierre, Peuchmaur, Michel, Riccardi, Carlo, Emilie, Dominique

“…Glucocorticoids and interleukin 10 (IL-10) prevent macrophage activation. In murine lymphocytes, glucocorticoids induce expression of glucocorticoid-induced…”
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Clinical characteristics and outcome of patients with neuroblastoma presenting genomic amplification of loci other than MYCN by Guimier, Anne, Ferrand, Sandrine, Pierron, Gaëlle, Couturier, Jérôme, Janoueix-Lerosey, Isabelle, Combaret, Valérie, Mosseri, Véronique, Thebaud, Estelle, Gambart, Marion, Plantaz, Dominique, Marabelle, Aurélien, Coze, Carole, Rialland, Xavier, Fasola, Sylvie, Lapouble, Eve, Fréneaux, Paul, Peuchmaur, Michel, Michon, Jean, Delattre, Olivier, Schleiermacher, Gudrun

“…Somatically acquired genomic alterations with MYCN amplification (MNA) are key features of neuroblastoma (NB), the most common extra-cranial malignant tumour…”
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Mast Cells and MCPT4 Chymase Promote Renal Impairment after Partial Ureteral Obstruction by Pons, Maguelonne, Ali, Liza, Beghdadi, Walid, Danelli, Luca, Alison, Marianne, Madjène, Lydia Celia, Calvo, Jessica, Claver, Julien, Vibhushan, Shamila, Åbrink, Magnus, Pejler, Gunnar, Poli-Mérol, Marie-Laurence, Peuchmaur, Michel, El Ghoneimi, Alaa, Blank, Ulrich

“…Obstructive nephropathy constitutes a major cause of pediatric renal progressive disease. The mechanisms leading to disease progression are still poorly…”
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