Search Results - "PETRUZZELLI, S"

Triple therapy (ICS/LABA/LAMA) in COPD: time for a reappraisal by Vanfleteren, Lowie, Fabbri, Leonardo M, Papi, Alberto, Petruzzelli, Stefano, Celli, Bartolome

“…Recently, two "fixed triple" single-inhaler combinations of an inhaled corticosteroid (ICS), a long-acting β -agonist (LABA), and a long-acting muscarinic…”
Get full text

Extrafine beclomethasone/formoterol in severe COPD patients with history of exacerbations by Wedzicha, J.A, Singh, D, Vestbo, J, Paggiaro, P.L, Jones, P.W, Bonnet-Gonod, F, Cohuet, G, Corradi, M, Vezzoli, S, Petruzzelli, S, Agusti, A

“…Summary The FORWARD study is a randomised, double-blind trial that compares the efficacy and safety of 48 weeks treatment with extrafine beclomethasone…”
Get full text

Extrafine triple therapy delays COPD clinically important deterioration vs ICS/LABA, LAMA, or LABA/LAMA by Singh, Dave, Fabbri, Leonardo M, Vezzoli, Stefano, Petruzzelli, Stefano, Papi, Alberto

“…Current pharmacological therapies for COPD improve quality of life and symptoms and reduce exacerbations. Given the progressive nature of COPD, it is arguably…”
Get full text

Beclomethasone/formoterol in the management of COPD: A randomised controlled trial by Calverley, P.M.A, Kuna, P, Monsó, E, Costantini, M, Petruzzelli, S, Sergio, F, Varoli, G, Papi, A, Brusasco, V

“…Summary Objectives To evaluate the effect of beclomethasone/formoterol versus budesonide/formoterol (non-inferiority) and versus formoterol (superiority) in…”
Get full text

Blood eosinophils: a biomarker of COPD exacerbation reduction with inhaled corticosteroids by Siddiqui, Salman H, Pavord, Ian D, Barnes, Neil C, Guasconi, Alessandro, Lettis, Sally, Pascoe, Steven, Petruzzelli, Stefano

“…Growing evidence suggests that blood eosinophil count is associated with patient responsiveness to inhaled corticosteroids (ICS). We performed post hoc…”
Get full text

Triple therapy in COPD: new evidence with the extrafine fixed combination of beclomethasone dipropionate, formoterol fumarate, and glycopyrronium bromide by Singh, Dave, Corradi, Massimo, Spinola, Monica, Papi, Alberto, Usmani, Omar S, Scuri, Mario, Petruzzelli, Stefano, Vestbo, Jørgen

“…The goals of COPD therapy are to prevent and control symptoms, reduce the frequency and severity of exacerbations, and improve exercise tolerance. The triple…”
Get full text

COPD increases the risk of squamous histological subtype in smokers who develop non-small cell lung carcinoma by Papi, A, Casoni, G, Caramori, G, Guzzinati, I, Boschetto, P, Ravenna, F, Calia, N, Petruzzelli, S, Corbetta, L, Cavallesco, G, Forini, E, Saetta, M, Ciaccia, A, Fabbri, L M

“…Background: Squamous cell carcinoma has a stronger association with tobacco smoking than other non-small cell lung cancers (NSCLC). A study was undertaken to…”
Get full text

The efficacy of extrafine beclomethasone dipropionate-formoterol fumarate in COPD patients who are not "frequent exacerbators": a post hoc analysis of the FORWARD study by Singh, Dave, Vezzoli, Stefano, Petruzzelli, Stefano, Papi, Alberto

“…The GOLD 2017 strategy document recommends that the pharmacological management of COPD patients be based on the risk of future exacerbations and the severity…”
Get full text

Corrigendum to “Extrafine beclomethasone/formoterol in severe COPD patients with history of exacerbations” [Respir Med 108 (2014) 1153–1162] by Wedzicha, J.A, Singh, D, Vestbo, J, Paggiaro, P.L, Jones, P.W, Bonnet Gonod, F, Cohuet, G, Corradi, M, Vezzoli, S, Petruzzelli, S, Agusti, A

“…BDP/FOR(N = 595) FOR(N = 591) Males, n (%) 408 (69%) 410 (69%) Age, years, mean ± SD 64.6 ± 8.6 63.9 ± 8.6 BMI, Kg/m2, mean ± SD 26.5 ± 5.4 26.5 ± 5.3 Current…”
Get full text

Gemcitabine monotherapy in elderly patients with advanced non-small cell lung cancer: A multicenter phase II study by Ricci, S, Antonuzzo, A, Galli, L, Tibaldi, C, Bertuccelli, M, Lopes Pegna, A, Petruzzelli, S, Algeri, R, Bonifazi, V, Fioretto, M.L, Orlandini, C, Conte, P.F

“…Background: This trial investigated the activity and toxicity of gemcitabine in previously untreated elderly (>70 years) patients with advanced (stage IIIB-IV)…”
Get full text

Asthma progression and mortality: the role of inhaled corticosteroids by O'Byrne, Paul, Fabbri, Leonardo M, Pavord, Ian D, Papi, Alberto, Petruzzelli, Stefano, Lange, Peter

“…Overall, asthma mortality rates have declined dramatically in the last 30 years, due to improved diagnosis and to better treatment, particularly in the 1990s…”
Get full text

D36 COPD: LABA, LAMA, ICS, AND COMBINATIONS: Comparison Of Extrafine Beclometasone Dipropionate/formoterol Fumarate (bdp/ff) Versus Other Double Combinations On Reduction Of Moderate/severe Exacerbations by Singh, D, Bizzi, A, Spinola, M, Petruzzelli, S, Papi, A

Get full text

Liver fibrosis score AARPRI predicts gynecological cancers in metabolic women by Crudele, L., De Matteis, C., Novielli, F., Petruzzelli, S., Cariello, M., Moschetta, A.

Get full text

C49 COPD: TREATMENT: Efficacy Of Chf5993, A Novel Triple Extrafine Combination Treatment In COPD Patients At High Risk Of Exacerbations: A Sub-Group Analysis Of The Trinity Study by Scuri, M, Spinola, M, Vezzoli, S, Muraro, A, Petruzzelli, S, Vestbo, J

“…Methods: TRINITY was a phase Ill, double-blind, 52-week study where 2691 severe/very severe COPD patients with a history of exacerbations were randomised to…”
Get full text

Effects of nicotine replacement therapy on markers of oxidative stress in cigarette smokers enrolled in a smoking cessation program by Petruzzelli, Stefano, Tavanti, Laura M., Pulerà, Nolita, Fornai, Edo, Puntoni, Roberto, Celi, Alessandro, Giuntini, Carlo

“…Twenty healthy, asymptomatic long-term cigarette smokers (8 males, 12 females; mean age: 43±9 years) were selected at random from a larger series receiving…”
Get full text

High-Dose Acetylcysteine in Idiopathic Pulmonary Fibrosis by Demedts, Maurits, Behr, Juergen, Buhl, Roland, Costabel, Ulrich, Dekhuijzen, Richard, Jansen, Henk M, MacNee, William, Thomeer, Michiel, Wallaert, Benoit, Laurent, François, Nicholson, Andrew G, Verbeken, Eric K, Verschakelen, Johny, Flower, Christopher D.R, Capron, Frédérique, Petruzzelli, Stefano, De Vuyst, Paul, van den Bosch, Jules M.M, Rodriguez-Becerra, Eulogio, Corvasce, Giuseppina, Lankhorst, Ida, Sardina, Marco, Montanari, Mauro

“…Idiopathic pulmonary fibrosis is a progressive disorder characterized by loss of lung function; there is no effective treatment. In this multinational,…”
Get full text

Pulmonary lipid peroxidation in cigarette smokers and lung cancer patients by Petruzzelli, S, Hietanen, E, Bartsch, H, Camus, A M, Mussi, A, Angeletti, C A, Saracci, R, Giuntini, C

“…Lipid peroxidation (LPO) was studied in lung tissues of patients with lung cancer (LC, n = 37) or nonlung cancer (NLC, n = 13) and its relationships with the…”
Get more information

C79 ADVANCING UNDERSTANDING OF OBSTRUCTIVE LUNG DISEASE: MEDICATIONS AND MECHANISMS OF DELIVERY: Cardiovascular Safety Of Extrafine Single Inhaler Triple Combination Of Beclometasone Dipropionate, Formoterol Fumarate, And Glycopyrronium Bromide In COPD: Results Of Safety Analysis From The Trilogy And Trinity Studies by Scuri, M, Singh, D, Papi, A, Corradi, M, Montagna, I, Francisco, C, Cohuet, G, Vezzoli, S, Muraro, A, Petruzzelli, S, Vestbo, J

“…In TRILOGY, patients were randomized (1:1) to an extrafine fixed triple combination of beclometasone dipropionate, formoterol fumarate, and glycopyrronium…”
Get full text

C79 ADVANCING UNDERSTANDING OF OBSTRUCTIVE LUNG DISEASE: MEDICATIONS AND MECHANISMS OF DELIVERY: Association Of Incident Pneumonia And Exacerbations With Extrafine Triple Therapy In One Single Inhaler In COPD Patients: A Post-Hoc Analysis From Trilogy And Trinity Studies by Scuri, M, Vestbo, J, Papi, A, Corradi, M, Spinola, M, Montagna, I, Francisco, C, Cohuet, G, Vezzoli, S, Muraro, A, Petruzzelli, S, Singh, D

“…Conclusions: This analysis confirms that, in two independent populations of COPD patients treated with an ICS-containing extrafine fixed triple combination,…”
Get full text

C79 ADVANCING UNDERSTANDING OF OBSTRUCTIVE LUNG DISEASE: MEDICATIONS AND MECHANISMS OF DELIVERY: Extrafine Single Inhaler Triple Therapy Reduces Use Of Rescue Medication In COPD Patients: Results From The Trinity Study by Scuri, M, Singh, D, Papi, A, Corradi, M, Montagna, I, Francisco, C, Cohuet, G, Vezzoli, S, Muraro, A, Petruzzelli, S, Vestbo, J

“…The reduction in the use of rescue medication is associated with such improvements in COPD patients and further supports their clinical relevance and sustained…”
Get full text