Search Results - "PETRONILLI, Valeria"

Calcium and regulation of the mitochondrial permeability transition by Giorgio, Valentina, Guo, Lishu, Bassot, Claudio, Petronilli, Valeria, Bernardi, Paolo

“…[Display omitted] •Permeability transition pore (PTP) is a Ca2+-activated channel whose prolonged openings can lead to depolarization, Ca2+ release and cell…”
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Dimers of mitochondrial ATP synthase form the permeability transition pore by Giorgio, Valentina, von Stockum, Sophia, Antoniel, Manuela, Fabbro, Astrid, Fogolari, Federico, Forte, Michael, Glick, Gary D., Petronilli, Valeria, Zoratti, Mario, Szabó, Ildikó, Lippe, Giovanna, Bernardi, Paolo

“…Here we define the molecular nature of the mitochondrial permeability transition pore (PTP), a key effector of cell death. The PTP is regulated by matrix…”
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Arginine 107 of yeast ATP synthase subunit g mediates sensitivity of the mitochondrial permeability transition to phenylglyoxal by Guo, Lishu, Carraro, Michela, Sartori, Geppo, Minervini, Giovanni, Eriksson, Ove, Petronilli, Valeria, Bernardi, Paolo

“…Modification with arginine-specific glyoxals modulates the permeability transition (PT) of rat liver mitochondria, with inhibitory or inducing effects that…”
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The unique histidine in OSCP subunit of F‐ATP synthase mediates inhibition of the permeability transition pore by acidic pH by Antoniel, Manuela, Jones, Kristen, Antonucci, Salvatore, Spolaore, Barbara, Fogolari, Federico, Petronilli, Valeria, Giorgio, Valentina, Carraro, Michela, Di Lisa, Fabio, Forte, Michael, Szabó, Ildikó, Lippe, Giovanna, Bernardi, Paolo

“…The permeability transition pore (PTP) is a Ca 2+ ‐dependent mitochondrial channel whose opening causes a permeability increase in the inner membrane to ions…”
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Cyclophilin D Modulates Mitochondrial F0F1-ATP Synthase by Interacting with the Lateral Stalk of the Complex by Giorgio, Valentina, Bisetto, Elena, Soriano, Maria Eugenia, Dabbeni-Sala, Federica, Basso, Emy, Petronilli, Valeria, Forte, Michael A., Bernardi, Paolo, Lippe, Giovanna

“…Blue native gel electrophoresis purification and immunoprecipitation of F0F1-ATP synthase from bovine heart mitochondria revealed that cyclophilin (CyP) D…”
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Phosphate Is Essential for Inhibition of the Mitochondrial Permeability Transition Pore by Cyclosporin A and by Cyclophilin D Ablation by Basso, Emy, Petronilli, Valeria, Forte, Michael A., Bernardi, Paolo

“…Energized mouse liver mitochondria displayed the same calcium retention capacity (a sensitive measure of the propensity of the permeability transition pore…”
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The mitochondrial permeability transition from in vitro artifact to disease target by Bernardi, Paolo, Krauskopf, Alexandra, Basso, Emy, Petronilli, Valeria, Blalchy‐Dyson, Elizabeth, Di Lisa, Fabio, Forte, Michael A.

“…The mitochondrial permeability transition pore is a high conductance channel whose opening leads to an increase of mitochondrial inner membrane permeability to…”
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Properties of the Permeability Transition Pore in Mitochondria Devoid of Cyclophilin D by Basso, Emy, Fante, Lisa, Fowlkes, Jonathan, Petronilli, Valeria, Forte, Michael A., Bernardi, Paolo

“…We have studied the properties of the permeability transition pore (PTP) in mitochondria from the liver of mice where the Ppif gene encoding for mitochondrial…”
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The mitochondrial permeability transition from yeast to mammals by Azzolin, Luca, von Stockum, Sophia, Basso, Emy, Petronilli, Valeria, Forte, Michael A., Bernardi, Paolo

“…Regulated permeability changes have been detected in mitochondria across species. We review here their key features, with the goal of assessing whether a…”
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Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels by Chiara, Federica, Castellaro, Diego, Marin, Oriano, Petronilli, Valeria, Brusilow, William S, Juhaszova, Magdalena, Sollott, Steven J, Forte, Michael, Bernardi, Paolo, Rasola, Andrea

“…Type II hexokinase is overexpressed in most neoplastic cells, and it mainly localizes on the outer mitochondrial membrane. Hexokinase II dissociation from…”
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Regulation of the Inner Membrane Mitochondrial Permeability Transition by the Outer Membrane Translocator Protein (Peripheral Benzodiazepine Receptor) by Šileikytė, Justina, Petronilli, Valeria, Zulian, Alessandra, Dabbeni-Sala, Federica, Tognon, Giuseppe, Nikolov, Peter, Bernardi, Paolo, Ricchelli, Fernanda

“…We studied the properties of the permeability transition pore (PTP) in rat liver mitochondria and in mitoplasts retaining inner membrane ultrastructure and…”
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The effects of idebenone on mitochondrial bioenergetics by Giorgio, Valentina, Petronilli, Valeria, Ghelli, Anna, Carelli, Valerio, Rugolo, Michela, Lenaz, Giorgio, Bernardi, Paolo

“…We have studied the effects of idebenone on mitochondrial function in cybrids derived from one normal donor (HQB17) and one patient harboring the G3460A/MT-ND1…”
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High-Conductance Channel Formation in Yeast Mitochondria is Mediated by F-ATP Synthase e and g Subunits by Carraro, Michela, Checchetto, Vanessa, Sartori, Geppo, Kucharczyk, Roza, di Rago, Jean-Paul, Minervini, Giovanni, Franchin, Cinzia, Arrigoni, Giorgio, Giorgio, Valentina, Petronilli, Valeria, Tosatto, Silvio C.E., Lippe, Giovanna, Szabó, Ildikó, Bernardi, Paolo

“…Background/Aims: The permeability transition pore (PTP) is an unselective, Ca 2+ -dependent high conductance channel of the inner mitochondrial membrane whose…”
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Properties of Ca2+ Transport in Mitochondria of Drosophila melanogaster by von Stockum, Sophia, Basso, Emy, Petronilli, Valeria, Sabatelli, Patrizia, Forte, Michael A., Bernardi, Paolo

“…We have studied the pathways for Ca2+ transport in mitochondria of the fruit fly Drosophila melanogaster. We demonstrate the presence of ruthenium red…”
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Respiratory Complex I Dysfunction Due to Mitochondrial DNA Mutations Shifts the Voltage Threshold for Opening of the Permeability Transition Pore toward Resting Levels by Porcelli, Anna Maria, Angelin, Alessia, Ghelli, Anna, Mariani, Elisa, Martinuzzi, Andrea, Carelli, Valerio, Petronilli, Valeria, Bernardi, Paolo, Rugolo, Michela

“…We have studied mitochondrial bioenergetics in HL180 cells (a cybrid line harboring the T14484C/ND6 and G14279A/ND6 mtDNA mutations of Leber hereditary optic…”
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A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis by TRINEI, Mirella, GIORGIO, Marco, PETRONILLI, Valeria, MINUCCI, Saverio, BERNARDI, Paolo, LANFRANCONE, Luisa, PELICCI, Pier Giuseppe, CICALESE, Angelo, BAROZZI, Sara, VENTURA, Andrea, MIGLIACCIO, Enrica, MILIA, Elisabetta, PADURA, Ines Martin, RAKER, Veronica A, MACCARANA, Marco

“…Correlative evidence links stress, accumulation of oxidative cellular damage and ageing in lower organisms and in mammals. We investigated their mechanistic…”
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The permeability transition pore as a mitochondrial calcium release channel: a critical appraisal by Bernardi, P, Petronilli, V

“…Mitochondria from a variety of sources possess an inner membrane channel, the permeability transition pore. The pore is a voltage-dependent channel, activated…”
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Modulation of the Mitochondrial Permeability Transition Pore by Pyridine Nucleotides and Dithiol Oxidation at Two Separate Sites by Costantini, P, Chernyak, B V, Petronilli, V, Bernardi, P

“…After accumulation of a Ca load, the addition of uncoupler to respiring rat liver mitochondria is followed by opening of the permeability transition pore…”
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Effects of fatty acids on mitochondria: implications for cell death by Penzo, Daniele, Tagliapietra, Chiara, Colonna, Raffaele, Petronilli, Valeria, Bernardi, Paolo

“…Fatty acids have prominent effects on mitochondrial energy coupling through at least three mechanisms: (i) increase of the proton conductance of the inner…”
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Interactions of Cyclophilin with the Mitochondrial Inner Membrane and Regulation of the Permeability Transition Pore, a Cyclosporin A-sensitive Channel by Nicolli, A, Basso, E, Petronilli, V, Wenger, R M, Bernardi, P

“…Mammalian mitochondria possess an inner membrane channel, the permeability transition pore (MTP), which can be inhibited by nanomolar concentrations of…”
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