Search Results - "PETROF, B. J"

Increased upper airway cytokines and oxidative stress in severe obstructive sleep apnoea by KIMOFF, R. J, HAMID, Q, DIVANGAHI, M, HUSSAIN, S, BAO, W, NAOR, N, PAYNE, R. J, ARIYARAJAH, A, MULRAIN, K, PETROF, B. J

“…Inflammation may contribute to upper airway pathophysiology in obstructive sleep apnoea (OSA). Our objective was to compare upper airway pro-inflammatory…”
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Sildenafil and cardiomyocyte-specific cGMP signaling prevent cardiomyopathic changes associated with dystrophin deficiency by Khairallah, M, Khairallah, R.J, Young, M.E, Allen, B.G, Gillis, M.A, Danialou, G, Deschepper, C.F, Petrof, B.J, Des Rosiers, C

“…We recently demonstrated early metabolic alterations in the dystrophin-deficient mdx heart that precede overt cardiomyopathy and may represent an early…”
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Effect of topical corticosteroids on allergic airway inflammation and disease severity in obstructive sleep apnoea by Lavigne, F., Petrof, B. J., Johnson, J. R., Lavigne, P., Binothman, N., Kassissia, G.-O., Al Samri, M., Giordano, C., Dubé, N., Hercz, D., Benedetti, A., Hamid, Q.

“…Summary Background The incidence of sleep‐related breathing disorders is correlated with lower and upper airway inflammatory diseases, such as asthma and…”
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Dystrophin Protects the Sarcolemma from Stresses Developed During Muscle Contraction by Petrof, Basil J., Shrager, Joseph B., Stedman, Hansell H., Kelly, Alan M., Sweeney, H. Lee

“…The protein dystrophin, normally found on the cytoplasmic surface of skeletal muscle cell membranes, is absent in patients with Duchenne muscular dystrophy as…”
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Dystrophin‐deficient cardiomyocytes are abnormally vulnerable to mechanical stress‐induced contractile failure and injury by Danialou, Gawiyou, Comtois, Alain S., Dudley, Roy, Karpati, George, Vincent, Geneviève, Des Rosiers, Christine, Petrof, Basil J.

“…ABSTRACT Although absence of the cytoskeletal protein dystrophin leads to dilated cardiomyopathy in humans, the functional role of dystrophin in cardiac muscle…”
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Bcl-2-associated autophagy regulator Naf-1 required for maintenance of skeletal muscle by CHANG, Natasha C, NGUYEN, Mai, BOURDON, Johanne, RISSE, Paul-André, MARTIN, James, DANIALOU, Gawiyou, RIZZUTO, Rosario, PETROF, Basil J, SHORE, Gordon C

“…Nutrient-deprivation autophagy factor-1 (NAF-1) was identified as an endoplasmic reticulum (ER) BCL-2-interacting protein, which functions to mediate the…”
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Transient immunosuppression by FK506 permits a sustained high-level dystrophin expression after adenovirus-mediated dystrophin minigene transfer to skeletal muscles of adult dystrophic (mdx) mice by Lochmüller, H, Petrof, B J, Pari, G, Larochelle, N, Dodelet, V, Wang, Q, Allen, C, Prescott, S, Massie, B, Nalbantoglu, J, Karpati, G

“…Adenovirus (AV)-mediated gene transfer into skeletal muscles of adult immune-competent animals has been limited by the fact that a cell-mediated immune attack…”
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Adaptations in myosin heavy chain expression and contractile function in dystrophic mouse diaphragm by Petrof, B J, Stedman, H H, Shrager, J B, Eby, J, Sweeney, H L, Kelly, A M

“…The X chromosome-linked muscular dystrophic (mdx) mouse lacks the subsarcolemmal protein dystrophin and thus represents a genetic homologue of human Duchenne…”
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Pharyngeal myopathy of loaded upper airway in dogs with sleep apnea by Petrof, B J, Pack, A I, Kelly, A M, Eby, J, Hendricks, J C

“…Recent work indicates that upper airway dilator muscles of individuals with obstructive sleep apnea syndrome (OSAS) demonstrate an increased level of activity…”
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Adenovirus-mediated utrophin gene transfer mitigates the dystrophic phenotype of mdx mouse muscles by Gilbert, R, Nalbantoglu, J, Petrof, B J, Ebihara, S, Guibinga, G H, Tinsley, J M, Kamen, A, Massie, B, Davies, K E, Karpati, G

“…Utrophin is a close homolog of dystrophin, the protein whose mutations cause Duchenne muscular dystrophy (DMD). Utrophin is present at low levels in normal and…”
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Diaphragm sarcolemmal injury is induced by sepsis and alleviated by nitric oxide synthase inhibition by LIN, M.-C, EBIHARA, S, QASIM EL DWAIRI, HUSSAIN, S. N. A, LIYING YANG, GOTTFRIED, S. B, COMTOIS, A, PETROF, B. J

“…Endotoxemia is associated with impaired diaphragm contractility, and increased nitric oxide (NO) production has recently been implicated in this phenomenon…”
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Respiratory muscles as a target for adenovirus-mediated gene therapy by Petrof, BJ

“…The protein dystrophin is absent in the muscles of patients with Duchenne muscular dystrophy (DMD) as well as dystrophin-deficient mice with muscular dystrophy…”
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Efficient muscle-specific transgene expression after adenovirus-mediated gene transfer in mice using a 1.35 kb muscle creatine kinase promoter/enhancer by LAROCHELLE, N, LOCHMÜLLER, H, NALBANTOGLU, J, ZHAO, J, JANI, A, HALLAUER, P, HASTINGS, K. E. M, MASSIE, B, PRESCOTT, S, PETROF, B. J, KARPATI, G

“…Replication-defective (E1-E3-deleted) human adenovirus vectors are a promising means of therapeutic gene delivery to skeletal muscle cells. Since the tropism…”
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Diaphragm muscle fiber injury after inspiratory resistive breathing by Zhu, E, Petrof, B J, Gea, J, Comtois, N, Grassino, A E

“…Five awake previously tracheotomized mongrel dogs were challenged with inspiratory resistive breathing (IRB). The mean peak tracheal pressure = -35.4 +/- 1.1…”
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Modulation of Starling forces and muscle fiber maturity permits adenovirus-mediated gene transfer to adult dystrophic (mdx) mice by the intravascular route by Cho, W K, Ebihara, S, Nalbantoglu, J, Gilbert, R, Massie, B, Holland, P, Karpati, G, Petrof, B J

“…Duchenne muscular dystrophy (DMD) and other inherited myopathies lead to progressive destruction of most skeletal muscles in the body, including those…”
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Does upper airway muscle injury trigger a vicious cycle in obstructive sleep apnea ? A hypothesis by PETROF, B. J, HENDRICKS, J. C, PACK, A. I

“…Recent studies have indicated that the level of neural activation of upper airway dilator muscles is abnormally elevated in patients with obstructive sleep…”
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Effect of CPAP on respiratory effort and dyspnea during exercise in severe COPD by Petrof, B J, Calderini, E, Gottfried, S B

“…Recent work has demonstrated the ability of continuous positive airway pressure (CPAP) to relieve dyspnea during exercise in patients with severe chronic…”
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Six1 and Eya1 Expression Can Reprogram Adult Muscle from the Slow-Twitch Phenotype into the Fast-Twitch Phenotype by Grifone, Raphaelle, Laclef, Christine, Spitz, François, Lopez, Soledad, Demignon, Josiane, Guidotti, Jacques-Emmanuel, Kawakami, Kiyoshi, Xu, Pin-Xian, Kelly, Robert, Petrof, Basil J., Daegelen, Dominique, Concordet, Jean-Paul, Maire, Pascal

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Immunosuppression by FK506 Markedly Prolongs Expression of Adenovirus-Delivered Transgene in Skeletal Muscles of Adult Dystrophic [mdx] Mice by Lochmuller, H., Petrof, B.J., Allen, C., Prescott, S., Massie, B., Karpati, G.

“…Adenovirus-mediated gene transfer into skeletal muscles of adult immune competent animals has been limited by the fact that a cellular immune attack of the…”
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Growth hormone does not prevent corticosteroid-induced changes in rat diaphragm structure and function by Petrof, B J, Gottfried, S B, Eby, J, Lamanca, J, Levine, S

“…The present study tested the hypothesis that growth hormone (GH), an anabolic agent, could prevent the abnormalities of diaphragm structure and function…”
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