Search Results - "PETRI, William A"
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Microglia: Immune Regulators of Neurodevelopment
Published in Frontiers in immunology (07-11-2018)“…Microglia, the tissue-resident macrophages of the central nervous system (CNS), have characterized roles in combating infection, clearing cellular debris, and…”
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Persistent gut microbiota immaturity in malnourished Bangladeshi children
Published in Nature (London) (19-06-2014)“…Bacterial species whose representation defines healthy postnatal assembly of the gut microbiota in Bangladeshi children during their first 2 years are…”
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Environmental enteropathy: critical implications of a poorly understood condition
Published in Trends in molecular medicine (01-06-2012)“…Environmental enteropathy (also called tropical enteropathy) is a subclinical condition caused by constant fecal–oral contamination and resulting in blunting…”
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4
Trogocytosis by Entamoeba histolytica contributes to cell killing and tissue invasion
Published in Nature (London) (24-04-2014)“…Entamoeba histolytica , the causative agent of fatal diarrhoeal disease in children in the developing world, is shown here to kill human cells by biting off…”
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5
Leptin Regulation of Immune Responses
Published in Trends in molecular medicine (01-02-2016)“…Leptin is a regulatory hormone with multiple roles in the immune system. We favor the concept that leptin signaling ‘licenses’ various immune cells to engage…”
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Tissue destruction and invasion by Entamoeba histolytica
Published in Trends in parasitology (01-06-2011)“…Entamoeba histolytica is the causative agent of amebiasis, a disease that is a major source of morbidity and mortality in the developing world. The potent…”
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TLR2 as a Therapeutic Target in Bacterial Infection
Published in Trends in molecular medicine (01-08-2020)“…Toll-like receptor (TLR) 2 recognizes and responds to threats early in bacterial infections and can influence the downstream immune response to the host’s…”
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Members of the human gut microbiota involved in recovery from Vibrio cholerae infection
Published in Nature (London) (20-11-2014)“…Recovery from cholera is characterized by a pattern of accumulation of bacterial taxa that shows similarities to the pattern of maturation of the gut…”
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The Impact of Systemic Inflammation on Neurodevelopment
Published in Trends in molecular medicine (01-09-2018)“…Inflammatory mediators affect the brain during development. Neurodevelopmental disorders such as autism spectrum disorders, cognitive impairment, cerebral…”
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10
Whole-genome sequencing in outbreak analysis
Published in Clinical microbiology reviews (01-07-2015)“…In addition to the ever-present concern of medical professionals about epidemics of infectious diseases, the relative ease of access and low cost of obtaining,…”
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Evaluation of K18- hACE2 Mice as a Model of SARS-CoV-2 Infection
Published in The American journal of tropical medicine and hygiene (01-09-2020)“…Murine models of SARS-CoV-2 infection are critical for elucidating the biological pathways underlying COVID-19. Because human angiotensin-converting enzyme 2…”
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A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium
Published in The Lancet infectious diseases (01-01-2015)“…Summary Cryptosporidium spp are well recognised as causes of diarrhoeal disease during waterborne epidemics and in immunocompromised hosts. Studies have also…”
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Exploring the role of environmental enteropathy in malnutrition, infant development and oral vaccine response
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (19-06-2015)“…Environmental enteropathy (EE) is a poorly defined state of intestinal inflammation without overt diarrhoea that occurs in individuals exposed over time to…”
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Specific Cryptosporidium antigens associate with reinfection immunity and protection from cryptosporidiosis
Published in The Journal of clinical investigation (15-08-2023)“…There is no vaccine to protect from cryptosporidiosis, a leading cause of diarrhea in infants in low- and middle-income countries. Here, we comprehensively…”
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Environmental Enteropathy: Elusive but Significant Subclinical Abnormalities in Developing Countries
Published in EBioMedicine (01-08-2016)“…Environmental enteropathy/Environmental enteric dysfunction (EE/EED) is a chronic disease of small intestine characterized by gut inflammation and barrier…”
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IL-33 drives group 2 innate lymphoid cell-mediated protection during Clostridium difficile infection
Published in Nature communications (20-06-2019)“…Clostridium difficile ( C. difficile ) incidence has tripled over the past 15 years and is attributed to the emergence of hypervirulent strains. While it is…”
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The role of interleukin 13 and the type 2 immune pathway in COVID-19: A review
Published in Annals of allergy, asthma, & immunology (01-06-2023)“…Although much has been learned about severe acute respiratory syndrome coronavirus 2 since December 2019, uneven global vaccine distribution, rapid viral…”
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Host Protective Mechanisms to Intestinal Amebiasis
Published in Trends in parasitology (01-02-2021)“…The protozoan parasite Entamoeba histolytica is the causative agent of amebiasis, an infection that manifests as colitis and, in some cases, liver abscess. A…”
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Type 3 Immunity during Clostridioides difficile Infection: Too Much of a Good Thing?
Published in Infection and immunity (17-12-2019)“…(formerly known as ) is the leading cause of hospital-acquired gastrointestinal infections in the United States and one of three urgent health care threats…”
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Gut microbiome communication with bone marrow regulates susceptibility to amebiasis
Published in The Journal of clinical investigation (01-08-2020)“…The microbiome provides resistance to infection. However, the underlying mechanisms are poorly understood. We demonstrate that colonization with the intestinal…”
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