Search Results - "PETERSON, Timothy E"

The role of extracellular vesicles and PD-L1 in glioblastoma-mediated immunosuppressive monocyte induction by Himes, Benjamin T, Peterson, Timothy E, de Mooij, Tristan, Garcia, Luz M Cumba, Jung, Mi-Yeon, Uhm, Sarah, Yan, David, Tyson, Jasmine, Jin-Lee, Helen J, Parney, Daniel, Abukhadra, Yasmina, Gustafson, Michael P, Dietz, Allan B, Johnson, Aaron J, Dong, Haidong, Maus, Rachel L, Markovic, Svetomir, Lucien, Fabrice, Parney, Ian F

“…Abstract Background Immunosuppression in glioblastoma (GBM) is an obstacle to effective immunotherapy. GBM-derived immunosuppressive monocytes are central to…”
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Isolation and Analysis of Plasma-Derived Exosomes in Patients With Glioma by Cumba Garcia, Luz M, Peterson, Timothy E, Cepeda, Mario A, Johnson, Aaron J, Parney, Ian F

“…Gliomas including glioblastoma (GBM) are the most common primary malignant brain tumors. Glioma extracellular vesicles (EVs) including exosomes have biological…”
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Modulating glioma-mediated myeloid-derived suppressor cell development with sulforaphane by Kumar, Ravi, de Mooij, Tristan, Peterson, Timothy E, Kaptzan, Tatiana, Johnson, Aaron J, Daniels, David J, Parney, Ian F

“…Glioblastoma is the most common primary tumor of the brain and has few long-term survivors. The local and systemic immunosuppressive environment created by…”
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Increasing glioma-associated monocytes leads to increased intratumoral and systemic myeloid-derived suppressor cells in a murine model by Chae, Michael, Peterson, Timothy E, Balgeman, Alexis, Chen, Selby, Zhang, Lei, Renner, Danielle N, Johnson, Aaron J, Parney, Ian F

“…Patients with glioblastoma multiforme (GBM) exhibit marked intratumoral and systemic immunosuppression. GBM is heavily infiltrated with monocytic cells…”
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Antitumor activity of novel pyrazole-based small molecular inhibitors of the STAT3 pathway in patient derived high grade glioma cells by Zhang, Liang, Peterson, Timothy E, Lu, Victor M, Parney, Ian F, Daniels, David J

“…Abnormal activation of signal transducer and activator of transcription 3 (STAT3) transcription factor has been observed in many human cancers with roles in…”
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Current Murine Models and New Developments in H3K27M Diffuse Midline Gliomas by Welby, John P, Kaptzan, Tatiana, Wohl, Anton, Peterson, Timothy E, Raghunathan, Aditya, Brown, Desmond A, Gupta, Shiv K, Zhang, Liang, Daniels, David J

“…Diffuse Midline Gliomas with Histone 3-Lysine-27-Methionine (H3K27M) mutation constitute the majority of Diffuse Intrinsic Pontine Glioma (DIPG), which is the…”
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Leptin upregulates the expression of plasminogen activator inhibitor-1 in human vascular endothelial cells by Singh, Prachi, Peterson, Timothy E., Barber, Kara R., Kuniyoshi, Fatima Sert, Jensen, Andrus, Hoffmann, Michal, Shamsuzzaman, Abu S.M., Somers, Virend K.

“…A prothrombotic state in obesity may be partially responsible for the higher incidence of atherosclerotic complications. However the factors responsible for…”
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Chronic Proteasome Inhibition Contributes to Coronary Atherosclerosis by Herrmann, Joerg, Saguner, Ardan M, Versari, Daniele, Peterson, Timothy E, Chade, Alejandro, Olson, Monica, Lerman, Lilach O, Lerman, Amir

“…The proteasome is responsible for the degradation of oxidized proteins, and proteasome inhibition has been shown to generate oxidative stress in vitro…”
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Exosome biopotentiated hydrogel restores damaged skeletal muscle in a porcine model of stress urinary incontinence by Rolland, Tyler J., Peterson, Timothy E., Singh, Raman Deep, Rizzo, Skylar A., Boroumand, Soulmaz, Shi, Ao, Witt, Tyra A., Nagel, Mary, Kisby, Cassandra K., Park, Sungjo, Rowe, Lois A., Paradise, Christopher R., Becher, Laura R. E., Paradise, Brooke D., Stalboerger, Paul G., Trabuco, Emanuel C., Behfar, Atta

“…Urinary incontinence afflicts up to 40% of adult women in the United States. Stress urinary incontinence (SUI) accounts for approximately one-third of these…”
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Selective stimulation of caveolar endocytosis by glycosphingolipids and cholesterol by Sharma, Deepak K, Brown, Jennifer C, Choudhury, Amit, Peterson, Timothy E, Holicky, Eileen, Marks, David L, Simari, Robert, Parton, Robert G, Pagano, Richard E

“…Internalization of some plasma membrane constituents, bacterial toxins, and viruses occurs via caveolae; however, the factors that regulate caveolar…”
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Human Endothelial Progenitor Cells Tolerate Oxidative Stress Due to Intrinsically High Expression of Manganese Superoxide Dismutase by He, Tongrong, Peterson, Timothy E, Holmuhamedov, Ekhson L, Terzic, Andre, Caplice, Noel M, Oberley, Larry W, Katusic, Zvonimir S

“…OBJECTIVE—Endothelial progenitor cells (EPCs) display a unique aptitude to promote angiogenesis and restore endothelial function of injured vessels. How…”
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Paracrine mitogenic effect of human endothelial progenitor cells: role of interleukin-8 by He, Tongrong, Peterson, Timothy E, Katusic, Zvonimir S

“…Endothelial progenitor cells (EPCs) play an important role in repair of vascular injury and neovascularization. Molecular mechanisms underlying vascular…”
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Autologous culture-modified mononuclear cells confer vascular protection after arterial injury by GULATI, Rajiv, JEVREMOVIC, Dragan, PETERSON, Timothy E, WITT, Tyra A, KLEPPE, Laurel S, MUESKE, Cheryl S, LERMAN, Amir, VILE, Richard G, SIMARI, Robert D

“…Bone marrow-derived cells have been shown to contribute to endothelial replacement after vascular injury. In vitro culture of peripheral blood mononuclear…”
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Caveolins and intracellular calcium regulation in human airway smooth muscle by Prakash, Y S, Thompson, Michael A, Vaa, Brianna, Matabdin, Ihaab, Peterson, Timothy E, He, Tongrong, Pabelick, Christina M

“…Regulation of intracellular Ca(2+) concentration ([Ca(2+)](i)) is a key factor in airway smooth muscle (ASM) tone. In vascular smooth muscle, specialized…”
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Author Correction: Exosome biopotentiated hydrogel restores damaged skeletal muscle in a porcine model of stress urinary incontinence by Rolland, Tyler J., Peterson, Timothy E., Singh, Raman Deep, Rizzo, Skylar A., Boroumand, Soulmaz, Shi, Ao, Witt, Tyra A., Nagel, Mary, Kisby, Cassandra K., Park, Sungjo, Rowe, Lois A., Paradise, Christopher R., Becher, Laura R. E., Paradise, Brooke D., Stalboerger, Paul G., Trabuco, Emanuel C., Behfar, Atta

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The hyperbilirubinemic Gunn rat is resistant to the pressor effects of angiotensin II by Pflueger, Axel, Croatt, Anthony J, Peterson, Timothy E, Smith, Leslie A, d'Uscio, Livius V, Katusic, Zvonimir S, Nath, Karl A

“…ANG II induces vasoconstriction, at least in part, by stimulating NADPH oxidase and generating reactive oxygen species. ANG II also induces heme oxygenase…”
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Short non-coding RNA sequencing of glioblastoma extracellular vesicles by de Mooij, Tristan, Peterson, Timothy E., Evans, Jared, McCutcheon, Brandon, Parney, Ian F.

“…Introduction Like all nucleated cells, glioblastoma (GBM) cells shed small membrane-encapsulated particles called extracellular vesicles (EVs). EVs can…”
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Intermittent hypoxia regulates vasoactive molecules and alters insulin-signaling in vascular endothelial cells by Sharma, Pragya, Dong, Yu, Somers, Virend K., Peterson, Timothy E., Zhang, Yuebo, Wang, Shihan, Li, Guangxi, Singh, Prachi

“…Vascular dysfunction and insulin resistance (IR) are associated with obstructive sleep apnea (OSA), which is characterized by frequent episodes of nocturnal…”
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Functional adaptation and remodeling of pulmonary artery in flow-induced pulmonary hypertension by Lam, Chen-Fuh, Peterson, Timothy E, Croatt, Anthony J, Nath, Karl A, Katusic, Zvonimir S

“…Patients with left-to-right shunt congenital heart disease may develop pulmonary hypertension. Perioperative mortality of these patients is high due to…”
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Opposing Effects of Reactive Oxygen Species and Cholesterol on Endothelial Nitric Oxide Synthase and Endothelial Cell Caveolae by Peterson, Timothy E, Poppa, Veronica, Ueba, Hiroto, Wu, Albert, Yan, Chen, Berk, Bradford C

“…Synthesis of nitric oxide (NO) by endothelial nitric oxide synthase (eNOS) is critical for normal vascular homeostasis. eNOS function is rapidly regulated by…”
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