Search Results - "PETERSON, Craig"

Heterochromatin: Hiding from the remodeling machines by Peterson, Craig L

“…In this issue of Molecular Cell, Sahu et al. find that shielding heterochromatin from SWI/SNF chromatin remodelers is essential to maintain and epigenetically…”
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Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes by Clapier, Cedric R., Iwasa, Janet, Cairns, Bradley R., Peterson, Craig L.

“…Key Points The dynamic regulation of chromatin involves four subfamilies of ATP-dependent nucleosome-remodelling complexes: imitation switch (ISWI),…”
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Chromatin and the genome integrity network by Papamichos-Chronakis, Manolis, Peterson, Craig L.

“…Key Points Three pathways for maintaining genomic integrity are influenced by chromatin: DNA damage repair, DNA replication and chromosome segregation. At DNA…”
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Chromatin dynamics: Interplay between remodeling enzymes and histone modifications by Swygert, Sarah G., Peterson, Craig L.

“…Chromatin dynamics play an essential role in regulating the accessibility of genomic DNA for a variety of nuclear processes, including gene transcription and…”
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Distinct transcriptional roles for Histone H3-K56 acetylation during the cell cycle in Yeast by Topal, Salih, Vasseur, Pauline, Radman-Livaja, Marta, Peterson, Craig L.

“…Dynamic disruption and reassembly of promoter-proximal nucleosomes is a conserved hallmark of transcriptionally active chromatin. Histone H3-K56 acetylation…”
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The insulator binding protein CTCF positions 20 nucleosomes around its binding sites across the human genome by Fu, Yutao, Sinha, Manisha, Peterson, Craig L, Weng, Zhiping

“…Chromatin structure plays an important role in modulating the accessibility of genomic DNA to regulatory proteins in eukaryotic cells. We performed an…”
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The Histone Chaperones FACT and Spt6 Restrict H2A.Z from Intragenic Locations by Jeronimo, Célia, Watanabe, Shinya, Kaplan, Craig D., Peterson, Craig L., Robert, François

“…H2A.Z is a highly conserved histone variant involved in several key nuclear processes. It is incorporated into promoters by SWR-C-related chromatin remodeling…”
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Genomic Nucleosome Organization Reconstituted with Pure Proteins by Krietenstein, Nils, Wal, Megha, Watanabe, Shinya, Park, Bongsoo, Peterson, Craig L., Pugh, B. Franklin, Korber, Philipp

“…Chromatin remodelers regulate genes by organizing nucleosomes around promoters, but their individual contributions are obfuscated by the complex in vivo milieu…”
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Global Regulation of H2A.Z Localization by the INO80 Chromatin-Remodeling Enzyme Is Essential for Genome Integrity by Papamichos-Chronakis, Manolis, Watanabe, Shinya, Rando, Oliver J., Peterson, Craig L.

“…INO80 is an evolutionarily conserved, ATP-dependent chromatin-remodeling enzyme that plays roles in transcription, DNA repair, and replication. Here, we show…”
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Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial by Gadde, Kishore M, Dr, Allison, David B, Prof, Ryan, Donna H, MD, Peterson, Craig A, MS, Troupin, Barbara, MD, Schwiers, Michael L, MS, Day, Wesley W, PhD

“…Summary Background Obesity is associated with a reduction in life expectancy and an increase in mortality from cardiovascular diseases, cancer, and other…”
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Nucleosome dynamics regulates DNA processing by Adkins, Nicholas L, Niu, Hengyao, Sung, Patrick, Peterson, Craig L

“…Double-strand-break repair by homologous recombination requires processing of the DNA ends by resection. In vitro and in vivo analysis of the Exo1 and…”
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Functional interaction between the RNA exosome and the sirtuin deacetylase Hst3 maintains transcriptional homeostasis by Bryll, Alysia R, Peterson, Craig L

“…Eukaryotic cells maintain an optimal level of mRNAs through unknown mechanisms that balance RNA synthesis and degradation. We found that inactivation of the…”
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A Histone Acetylation Switch Regulates H2A.Z Deposition by the SWR-C Remodeling Enzyme by Watanabe, Shinya, Radman-Livaja, Marta, Rando, Oliver J., Peterson, Craig L.

“…The histone variant H2A.Z plays key roles in gene expression, DNA repair, and centromere function. H2A.Z deposition is controlled by SWR-C chromatin remodeling…”
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Mechanisms that regulate localization of a DNA double-strand break to the nuclear periphery by Oza, Pranav, Jaspersen, Sue L, Miele, Adriana, Dekker, Job, Peterson, Craig L

“…DNA double-strand breaks (DSBs) are among the most deleterious forms of DNA lesions in cells. Here we induced site-specific DSBs in yeast cells and monitored…”
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SWI/SNF recruitment to a DNA double-strand break by the NuA4 and Gcn5 histone acetyltransferases by Bennett, Gwendolyn, Peterson, Craig L.

“…•Gcn5 HAT is required for SWI/SNF recruitment to a DSB.•Gcn5 HAT is required for optimal DSB resection.•NuA4 HAT is required for SWI/SNF recruitment to a…”
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Ruler elements in chromatin remodelers set nucleosome array spacing and phasing by Oberbeckmann, Elisa, Niebauer, Vanessa, Watanabe, Shinya, Farnung, Lucas, Moldt, Manuela, Schmid, Andrea, Cramer, Patrick, Peterson, Craig L., Eustermann, Sebastian, Hopfner, Karl-Peter, Korber, Philipp

“…Arrays of regularly spaced nucleosomes dominate chromatin and are often phased by alignment to reference sites like active promoters. How the distances between…”
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H2A.Z deposition by SWR1C involves multiple ATP-dependent steps by Fan, Jiayi, Moreno, Andrew T., Baier, Alexander S., Loparo, Joseph J., Peterson, Craig L.

“…Histone variant H2A.Z is a conserved feature of nucleosomes flanking protein-coding genes. Deposition of H2A.Z requires ATP-dependent replacement of…”
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The Ino80 chromatin-remodeling enzyme regulates replisome function and stability by Papamichos-Chronakis, Manolis, Peterson, Craig L

“…Previous studies have demonstrated essential roles for ATP-dependent chromatin-remodeling and chromatin-modifying enzymes in gene transcription and DNA repair,…”
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Women's Roles on U.S. Fortune 500 Boards: Director Expertise and Committee Memberships by Peterson, Craig A., Philpot, James

“…This study examines the presence and roles of female directors of U.S. Fortune 500 firms, focusing on committee assignments and director background. Prior work…”
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Yeast Sirtuin Family Members Maintain Transcription Homeostasis to Ensure Genome Stability by Feldman, Jessica L, Peterson, Craig L

“…The mammalian sirtuin, SIRT6, is a key tumor suppressor that maintains genome stability and regulates transcription, though how SIRT6 family members control…”
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