Search Results - "PETERS, Erna"

Inhibition of 14q32 MicroRNAs miR-329, miR-487b, miR-494, and miR-495 Increases Neovascularization and Blood Flow Recovery After Ischemia by Welten, Sabine M.J, Bastiaansen, Antonius J.N.M, de Jong, Rob C.M, de Vries, Margreet R, Peters, Erna A.B, Boonstra, Martin C, Sheikh, Søren P, Monica, Nicola La, Kandimalla, Ekambar R, Quax, Paul H.A, Nossent, A Yaël

“…RATIONALE:Effective neovascularization is crucial for recovery after cardiovascular events. OBJECTIVE:Because microRNAs regulate expression of up to several…”
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Lysine Acetyltransferase PCAF Is a Key Regulator of Arteriogenesis by Bastiaansen, Antonius J.N.M, Ewing, Mark M, de Boer, Hetty C, van der Pouw Kraan, Tineke C, de Vries, Margreet R, Peters, Erna A.B, Welten, Sabine M.J, Arens, Ramon, Moore, Scott M, Faber, James E, Jukema, J Wouter, Hamming, Jaap F, Nossent, A Yaël, Quax, Paul H.A

“…OBJECTIVE—Therapeutic arteriogenesis, that is, expansive remodeling of preexisting collaterals, using single-action factor therapies has not been as successful…”
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von Willebrand factor deficiency leads to impaired blood flow recovery after ischaemia in mice by de Vries, Margreet R, Peters, Erna A B, Quax, Paul H A, Nossent, A Yaël

“…Neovascularisation, i. e. arteriogenesis and angiogenesis, is an inflammatory process. Therefore attraction and extravasation of leukocytes is essential for…”
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TLR accessory molecule RP105 (CD180) is involved in post-interventional vascular remodeling and soluble RP105 modulates neointima formation by Karper, Jacco C, Ewing, Mark M, de Vries, Margreet R, de Jager, Saskia C A, Peters, Erna A B, de Boer, Hetty C, van Zonneveld, Anton-Jan, Kuiper, Johan, Huizinga, Eric G, Brondijk, T Harma C, Jukema, J Wouter, Quax, Paul H A

“…RP105 (CD180) is TLR4 homologue lacking the intracellular TLR4 signaling domain and acts a TLR accessory molecule and physiological inhibitor of…”
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Blocking Toll-Like Receptors 7 and 9 Reduces Postinterventional Remodeling via Reduced Macrophage Activation, Foam Cell Formation, and Migration by Karper, Jacco C, Ewing, Mark M, Habets, Kim L.L, de Vries, Margreet R, Peters, Erna A.B, van Oeveren-Rietdijk, Annemarie M, de Boer, Hetty C, Hamming, Jaap F, Kuiper, Johan, Kandimalla, Ekambar R, La Monica, Nicola, Jukema, J Wouter, Quax, Paul H.A

“…OBJECTIVE—The role of toll-like receptors (TLRs) in vascular remodeling is well established. However, the involvement of the endosomal TLRs is unknown. Here,…”
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TLR4 accessory molecule RP105 (CD180) regulates monocyte-driven arteriogenesis in a murine hind limb ischemia model by Bastiaansen, Antonius J N M, Karper, Jacco C, Wezel, Anouk, de Boer, Hetty C, Welten, Sabine M J, de Jong, Rob C M, Peters, Erna A B, de Vries, Margreet R, van Oeveren-Rietdijk, Annemarie M, van Zonneveld, Anton Jan, Hamming, Jaap F, Nossent, A Yaël, Quax, Paul H A

“…We investigated the role of the TLR4-accessory molecule RP105 (CD180) in post-ischemic neovascularization, i.e. arteriogenesis and angiogenesis. TLR4-mediated…”
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Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization by Baganha, Fabiana, de Jong, Rob C. M., Peters, Erna A., Voorham, Wietske, Jukema, J. Wouter, Delibegovic, Mirela, de Vries, Margreet R., Quax, Paul H. A.

“…Objective Statins pleiotropically provide additional benefits in reducing atherosclerosis, but their effects on intraplaque angiogenesis (IPA) and hemorrhage…”
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Inhibition of Mef2a Enhances Neovascularization via Post-transcriptional Regulation of 14q32 MicroRNAs miR-329 and miR-494 by Welten, Sabine M.J., de Vries, Margreet R., Peters, Erna A.B., Agrawal, Sudhir, Quax, Paul H.A., Nossent, A. Yaël

“…Improving the efficacy of neovascularization is a promising strategy to restore perfusion of ischemic tissues in patients with peripheral arterial disease. The…”
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CCR7‐CCL19/CCL21 Axis is Essential for Effective Arteriogenesis in a Murine Model of Hindlimb Ischemia by Nossent, A. Yaël, Bastiaansen, Antonius J. N. M., Peters, Erna A. B., Vries, Margreet R., Aref, Zeen, Welten, Sabine M. J., Jager, Saskia C. A., Pouw Kraan, Tineke C. T. M., Quax, Paul H. A.

“…Background In order to identify factors that stimulate arteriogenesis after ischemia, we followed gene expression profiles in two extreme models for collateral…”
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Quaking, an RNA-Binding Protein, Is a Critical Regulator of Vascular Smooth Muscle Cell Phenotype by van der Veer, Eric P, de Bruin, Ruben G, Kraaijeveld, Adriaan O, de Vries, Margreet R, Bot, Ilze, Pera, Tonio, Segers, Filip M, Trompet, Stella, van Gils, Janine M, Roeten, Marko K, Beckers, Cora M, van Santbrink, Peter J, Janssen, Anique, van Solingen, Coen, Swildens, Jim, de Boer, Hetty C, Peters, Erna A, Bijkerk, Roel, Rousch, Mat, Doop, Merijn, Kuiper, Johan, Schalij, Martin Jan, van der Wal, Allard C, Richard, Stéphane, van Berkel, Theo J.C, Pickering, J Geoffrey, Hiemstra, Pieter S, Goumans, Marie Jose, Rabelink, Ton J, de Vries, Antoine A.F, Quax, Paul H.A, Jukema, J Wouter, Biessen, Erik A.L, van Zonneveld, Anton Jan

“…RATIONALE:RNA-binding proteins are critical post-transcriptional regulators of RNA and can influence pre-mRNA splicing, RNA localization, and stability. The…”
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Deficiency of the TLR4 analogue RP105 aggravates vein graft disease by inducing a pro-inflammatory response by Wezel, Anouk, de Vries, Margreet R., Maassen, Johanna M., Kip, Peter, Peters, Erna A., Karper, Jacco C., Kuiper, Johan, Bot, Ilze, Quax, Paul H. A.

“…Venous grafts are often used to bypass occlusive atherosclerotic lesions; however, poor patency leads to vein graft disease. Deficiency of TLR4, an…”
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P300/CBP Associated Factor (PCAF) Deficiency Enhances Diet-Induced Atherosclerosis in ApoE3Leiden Mice via Systemic Inhibition of Regulatory T Cells by de Jong, Alwin, de Jong, Rob C. M., Peters, Erna A., Arens, Ramon, Jukema, J. Wouter, de Vries, Margreet R., Quax, Paul H. A.

“…Background: Inflammatory stimuli induced by NF-kB drive atherosclerotic lesion formation. The epigenetic P300/CBP associated factor (PCAF)…”
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PS210. Inhibition of VEGFR2 Reduces Angiogenic Microvessel Leakiness in Murine Vein Graft Atherosclerotic Lesions and Increased Plaque Stability by de Vries, Margreet, de Jong, Rob C, Peters, Erna H, Hamming, Jaap F, Goumans, Marie José, van Bockel, Hajo J, Quax, Paul H

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Membrane-type matrix metalloproteinase-mediated angiogenesis in a fibrin-collagen matrix by Collen, Annemie, Hanemaaijer, Roeland, Lupu, Florea, Quax, Paul H.A., van Lent, Natascha, Grimbergen, Jos, Peters, Erna, Koolwijk, Pieter, van Hinsbergh, Victor W.M.

“…Adult angiogenesis, associated with pathologic conditions, is often accompanied by the formation of a fibrinous exudate. This temporary matrix consists mainly…”
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Abstract 11919: Igg1 Phosphorylcholine Diminishes Murine Atherosclerosis and Ameliorates Plaque Stability via Reduced Intraplaque Angiogenesis and Hemorrhage by de Vries, Margreet R, Baganha, Fabiana, Peters, Erna, Pettersson, Knut, Quax, Paul H

“…IntroductionPhosphorylcholine (PC), one of the main oxLDL epitopes, is an important pro-inflammatory damage associated molecular pattern. Epidemiologic data…”
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Aminopeptidase inhibitor bestatin stimulates microvascular endothelial cell invasion in a fibrin matrix by van Hensbergen, Yvette, Broxterman, Henk J, Peters, Erna, Rana, Sareena, Elderkamp, Yvonne W, van Hinsbergh, Victor W M, Koolwijk, Pieter

“…The aminopeptidase inhibitor bestatin has been shown to have anti-angiogenic effects in a number of model systems. These effects are thought to result from…”
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Vein Graft Disease is Prevented by Toll-like Receptor 3 Via Type-I Interferon Induced Decrease of Inflammatory Responses by de Vries, Margreet, Simons, Karin, Peters, Erna, Jukema, Wouter, Hamming, Jaap

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Abstract 15140: VEGFR2 Blockade in Murine Vein Grafts Reduces Intraplaque Hemorrhage due to Enhanced Plaque Neovessel Maturation by de Vries, Margreet R, Peters, Erna A, Hamming, Jaap F, Goumans, MarieJosé T, Quax, Paul H

“…IntroductionVein graft patency rates are poor due to the development of extensive neointimal thickening, atherosclerosis and lesion instability. We have…”
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Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases by Vries, M. R., Ewing, M. M., Jong, R. C. M., MacArthur, M. R., Karper, J. C., Peters, E. A. B., Nordzell, M., Karabina, S. A. P., Sexton, D., Dahlbom, I., Bergman, A., Mitchell, J. R., Frostegård, J., Kuiper, J., Ninio, E., Jukema, J. W., Pettersson, K., Quax, P. H. A.

“…Background Phosphorylcholine (PC) is an important pro‐inflammatory damage‐associated molecular pattern. Previous data have shown that natural IgM anti‐PC…”
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Abstract 412: Radio Protective P105 Deficiency Aggravates Vein Graft Disease And Lesion Instability via Increased Inflammatory Responses by de Vries, Margreet R, Wezel, Anouk, Peters, Erna H, Karper, Jacco C, Kuiper, Johan, Bot, Ilze, Quax, Paul H

“…Abstract only Aim: Vein grafts are often used to bypass atherosclerotic lesions; however, patency rates are troublesome due to the development of vein graft…”
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