Search Results - "PETERING, D. H"

Cadmium and lead interactions with transcription factor IIIA from Xenopus laevis: a model for zinc finger protein reactions with toxic metal ions and metallothionein by Petering, D.H, Huang, M, Moteki, S, Shaw III, C.F

“…Zinc finger proteins comprise the largest class of eukaryotic transcription factors. The metal binding sites in these proteins have been proposed as plausible…”
Get full text

Properties of the reaction of cis-dichlorodiammineplatinum(II) with metallothionein by A Pattanaik, G Bachowski, J Laib, D Lemkuil, C F Shaw, 3rd, D H Petering, A Hitchcock, L Saryan

“…Properties of the reactions of cis-dichlorodiammine Pt(II) and related complexes with zinc metallothionein or apometallothionein have been investigated. During…”
Get full text

Interprotein metal ion exchange between cadmium-carbonic anhydrase and apo- or zinc-metallothionein by Ejnik, J, Muñoz, A, Gan, T, Shaw, 3rd, C F, Petering, D H

“…The ligand substitution reactions of cadmium-carbonic anhydrase with EDTA and pyridine-2,6-dicarboxylic acid were compared with one in which rabbit…”
Get full text

Structure−Reactivity Relationships among Metallothionein Three-Metal Domains:  Role of Non-Cysteine Amino Acid Residues in Lobster Metallothionein and Human Metallothionein-3 by Muñoz, Amalia, Petering, David H, Shaw, C. Frank

“…Metallothionein (MT) domains of different origins, exhibiting distinct, highly conserved cysteine positions, show differences in metal−cysteine coordination…”
Get full text

Comparative Binding Properties of Metallobleomycins with DNA 10-mers by Li, Wenbao, Zhao, Chunqing, Xia, Chuanwu, Antholine, William E, Petering, David H

“…Properties of the interaction of bleomycin (Blm) and metallobleomycins [M = Zn, Cu(II), Fe(III), and HO2−Co(III)] with site-specific and nonspecific DNA…”
Get full text

Model reactions of Cr (VI) with DNA mediated by thiol species by Krepkiy, D, Antholine, W E, Myers, C, Petering, D H

“…Model reactions were devised to investigate the capacity of physiologically interesting thiol compounds to mediate reactions between CrO4(2-) (Cr (VI)) and…”
Get full text

The requirements for stable metallothionein clusters examined using synthetic lobster domains by Muñoz, A., Petering, D.H., Shaw III, C.F.

“…Metallothioneins (MTs) are small, cysteine-rich proteins which detoxify xenobiotic metals such as cadmium (Cd) and mercury (Hg). In crustaceans and mammals…”
Get full text

Iron requirement for cellular DNA damage and growth inhibition by hydrogen peroxide and bleomycin by Radtke, K, Lornitzo, F.A, Byrnes, R.W, Antholine, W.E, Petering, D.H

“…Studies with Euglena gracilis and HL-60 cells have assessed the need for intracellular iron in the mechanisms of inhibition of cell growth and DNA damage by…”
Get full text

NMR Determination of the Structures of Peroxycobalt(III) Bleomycin and Cobalt(III) Bleomycin, Products of the Aerobic Oxidation of Cobalt(II) Bleomycin by Dioxygen by Xu, Robert X, Nettesheim, David, Otvos, James D, Petering, David H

“…The oxidation of Co(II) bleomycin A2 by dioxygen leads to two products, HO2-Co(III) bleomycin A2 (form I) and Co(III) bleomycin A2 (form II). 1H NMR chemical…”
Get full text

The role of redox-active metals in the mechanism of action of bleomycin by Petering, D H, Byrnes, R W, Antholine, W E

“…Belomycin is a glycopeptide antibiotic routinely used to treat human cancer. It is commonly thought to exert its biological effects as a metallodrug, which…”
Get more information

Metallothionein reacts with Fe2+ and NO to form products with A g = 2.039 ESR signal by Kennedy, M C, Gan, T, Antholine, W E, Petering, D H

“…The interaction of metallothionein, Fe2+, and nitric oxide has been examined by electron spin resonance spectroscopy. When either apoMT 2 or Zn-MT 2 from…”
Get more information

Orientation of dioxygen bound to cobalt(II) bleomycin-DNA fibers by Chikira, M, Antholine, W E, Petering, D H

“…The molecular oxygen adduct of Co(II)-bleomycin is stable for long periods when bound to salmon sperm DNA at large ratios of polymer to drug. According to ESR…”
Get full text

Reaction of Co(II)bleomycin with dioxygen by Xu, R X, Antholine, W E, Petering, D H

“…The reaction of Co(II)bleomycin with dioxygen has been investigated. Dioxygen binds to the Co(II) complex within the time of mixing according to electron spin…”
Get full text

Orientation of non-blue cupric complexes on DNA fibers by CHIKIRA, M, SATO, T, ANTHOLINES, W. E, PETERING, D. H

“…Three different orientations of non-blue, type 2 cupric complexes on DNA fibers are obtained from EPR data. The cupric complex of bleomycin, CuBlm, binds as…”
Get full text

Surface Chemistry and Biological Pathogenicity of Silicates: An X-Ray Photoelectron Spectroscopic Study by Seal, Sudipta, Krezoski, Susan, Barr, Tery L., Petering, David H., Klinowski, Jacek, Evans, Peter H.

“…We extend our electron spectroscopy for chemical analysis studies of the chemistry of silicates to provide direct surface chemical information on the…”
Get full text

Reaction of 3-ethoxy-2-oxobutyraldehyde bis(thiosemicarbazonato) Cu(II) with Ehrlich cells. Binding of copper to metallothionein and its relationship to zinc metabolism and cell proliferation by Kraker, A, Krezoski, S, Schneider, J, Minkel, D, Petering, D H

“…The copper complex of 3-ethoxy-2-oxobutyraldehyde bis(thiosemicarbazone) or CuKTS is reduced and dissociated upon reaction with Ehrlich cells. Titration of the…”
Get full text

Cadmium Decreases SGLT1 Messenger RNA in Mouse Kidney Cells by Blumenthal, Samuel S., Ren, Lifen, Lewand, Donna L., Krezoski, Susan K., Petering, David H.

“…Mouse renal cortical tubule cells in primary culture exposed to cadmium (Cd2+) develop decreased Na+-glucose cotransport activity as measured by uptake of the…”
Get full text

Oxidative stress induced by a copper-thiosemicarbazone complex by Byrnes, Robert W, Mohan, Madan, Antholine, William E, Xu, Robert X, Petering, David H

“…Copper thiosemicarbazones cause considerable oxidative stress. This effect may be related to their cytotoxicity. In the present work, the chemical and cellular…”
Get full text

Reaction of DNA-bound Co(II)bleomycin with dioxygen by Xu, R X, Antholine, W E, Petering, D H

“…The aerobic oxidation of Co(II)bleomycin bound to calf thymus DNA has been investigated in relation to the mechanism of reaction in solution in the absence of…”
Get full text

Repair of Bleomycin-Induced DNA Double-Strand Breakage in Ehrlich Ascites Tumor Cells by Byrnes, Robert W., Petering, David H.

“…The effect of 1,10-phenanthroline (OP) on repair of bleomycin (Bleo)-induced double-strand breaks in Ehrlich ascites tumor cells was studied using…”
Get full text