Search Results - "PESCOVITZ, O. H"

Spontaneous feminization in a 46,XX female patient with congenital lipoid adrenal hyperplasia due to a homozygous frameshift mutation in the steroidogenic acute regulatory protein by BOSE, H. S, PESCOVITZ, O. H, MILLER, W. L

“…The most severe form of congenital adrenal hyperplasia (CAH) is lipoid CAH. It was once thought that this disease was due to mutations in the cholesterol…”
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Current Age of Onset of Puberty by Rosenfield, Robert L, Bachrach, Laura K, Chernausek, Steven D, Gertner, Joseph M, Gottschalk, Michael, Hardin, Dana S, Pescovitz, Ora H, Saenger;, Paul, Herman-Giddens, Marcia E, Slora, Eric, Wasserman, Richard

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Molecular analysis of LHX3 and PROP-1 in pituitary hormone deficiency patients with posterior pituitary ectopia by SLOOP, K. W, WALVOORD, E. C, SHOWALTER, A. D, PESCOVITZ, O. H, RHODES, S. J

“…The cause of posterior pituitary ectopia associated with anterior pituitary hormone deficiencies is unknown. We describe children with combined pituitary…”
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Combined use of growth hormone and gonadotropin-releasing hormone analogues in precocious puberty : Theoretic and practical considerations by WALVOORD, E. C, PESCOVITZ, O. H

“…The rationale underlying the use of gonadotropin-releasing hormone analogues (GnRHa) to treat patients with central precocious puberty is reviewed. GnRHa are…”
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Disorders of puberty : Inactivating and activating molecular mutations by DIMEGLIO, L. A, PESCOVITZ, O. H

“…Recent developments have increased our understanding of the molecular mechanisms that are responsible for several disorders of puberty. Specific gene mutations…”
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Oral administration of growth hormone (GH) releasing peptide-mimetic MK-677 stimulates the GH/insulin-like growth factor-I axis in selected GH-deficient adults by CHAPMAN, I. M, PESCOVITZ, O. H, THORNER, M. O, MURPHY, G, TREEP, T, CERCHIO, K. A, KRUPA, D, GERTZ, B, POLVINO, W. J, SKILES, E. H, PEZZOLI, S. S

“…To determine the effect of the GH releasing peptide (GHRP)-mimetic, MK-677, on the GH/insulin-like growth factor-I (IGF-I) axis in selected GH-deficient…”
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Müllerian agenesis: An update by Lindenman, Elizabeth, Shepard, Marguerite K., Pescovitz, Ora Hirsch

“…Recently, many advances have been made in the study of sexual differentiation, including the discoveries of the gene for antimüllerian hormone as well as the…”
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Use of an ultrasensitive recombinant cell bioassay to determine estrogen levels in girls with precocious puberty treated with a luteinizing hormone-releasing hormone agonist by KLEIN, K. O, BARON, J, BARNES, K. M, PESCOVITZ, O. H, CUTLER, G. B

“…Although treatment of girls with precocious puberty should ideally restore estradiol levels to the normal prepubertal range, treatment effectiveness has…”
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Bone mineral density during treatment of central precocious puberty by Neely, E.Kirk, Bachrach, Laura K., Hintz, Raymond L., Habiby, Reema L., Slemenda, Charles W., Feezle, Lori, Pescovitz, Ora H.

“…Treatment of adults with gonadotropin releasing hormone analogs has resulted in rapid loss in bone mineral density (BMD). We measured lumbar and femoral neck…”
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The clitoral index: a determination of clitoral size in normal girls and in girls with abnormal sexual development by Sane, K, Pescovitz, O H

“…Clitoral measurements were obtained in normal children; small increases in clitoral dimensions were associated with growth and puberty. Patients with androgen…”
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Testing the hypothalamic-pituitary-adrenal axis in survivors of childhood brain and skull-based tumors by RAVI SHANKAR, R, JAKACKI, R. I, HAIDER, A, LEE, M. W, PESCOVITZ, O. H

“…The objective of this study was to determine whether a low dose of ACTH (0.2 microg/kg) improves the sensitivity of ACTH testing in detecting…”
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Thyroid dysfunction following bone marrow transplantation: long-term follow-up of 80 pediatric patients by Katsanis, E, Shapiro, R S, Robison, L L, Haake, R J, Kim, T, Pescovitz, O H, Ramsay, N K

“…Thyroid function was evaluated in children surviving disease-free for 2 years or more following bone marrow transplantation (BMT) for severe aplastic anemia…”
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Peptides derived from pro-growth hormone-releasing hormone activate p38 mitogen-activated protein kinase in GH3 pituitary cells by Steinmetz, R, Zeng, P, King, D W, Walvoord, E, Pescovitz, O H

“…Posttranslational processing of the pro-growth hormone-releasing hormone (proGHRH) peptide can result in the formation of at least two peptide products: GHRH…”
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Variations on a theme: testis-derived neuropeptide hormones by DiMeglio, L A, Steinmetz, R, Pescovitz, O H

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Severe endocrine and nonendocrine manifestations of the McCune-Albright syndrome associated with activating mutations of stimulatory G protein GS by Shenker, A, Weinstein, L S, Moran, A, Pescovitz, O H, Charest, N J, Boney, C M, Van Wyk, J J, Merino, M J, Feuillan, P P, Spiegel, A M

“…McCune-Albright syndrome (MCAS) is a sporadic disease classically including polyostotic fibrous dysplasia, café au lait spots, sexual precocity, and other…”
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Height outcome in congenital adrenal hyperplasia caused by 21-hydroxylase deficiency: A meta-analysis by Eugster, Erica A., DiMeglio, Linda A., Wright, James C., Freidenberg, Gary R., Seshadri, Roopa, Pescovitz, Ora H.

“…Objective: To investigate adult heights attained by patients with 21-hydroxylase deficiency and to perform a meta-analysis of height outcomes reported in this…”
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Identification of a rat GHRH-like substance and its messenger RNA in rat testis by Berry, S A, Pescovitz, O H

“…The adult testis is a source of hypothalamic neuropeptides including TRH, GnRH, POMC and CRF. The role of these neuropeptides as paracrine regulators of…”
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Treatment of familial male precocious puberty with spironolactone and testolactone by Laue, L, Kenigsberg, D, Pescovitz, O H, Hench, K D, Barnes, K M, Loriaux, D L, Cutler, Jr, G B

“…Because the pubertal growth spurt in boys appears to be mediated by both androgens and estrogens, we hypothesized that blockade of both androgen action and…”
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The NIH experience with precocious puberty: diagnostic subgroups and response to short-term luteinizing hormone releasing hormone analogue therapy by Pescovitz, O H, Comite, F, Hench, K, Barnes, K, McNemar, A, Foster, C, Kenigsberg, D, Loriaux, D L, Cutler, Jr, G B

“…Between 1979 and 1983, 129 children (95 girls) with precocious puberty were referred to the National Institutes of Health and received treatment for at least 6…”
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Gonadotrophin and prolactin secretory dynamics in girls with normal puberty, idiopathic precocious puberty and precocious puberty due to hypothalamic hamartoma by Uriarte, M. Mercedes, Oerter Klein, Karen, Barnes, Kevin M., Pescovitz, Ora H., Loriaux, D. Lynn, Cutler, Jr, Gordon B.

“…OBJECTIVE This study was designed to test the hypothesis that hypothalamic hamartoma causes precocious puberty through a different neuroendocrine mechanism…”
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