Search Results - "PERTL, Ursula"

A DNA vaccine against VEGF receptor 2 prevents effective angiogenesis and inhibits tumor growth by Reisfeld, Ralph A, Niethammer, Andreas G, Xiang, Rong, Becker, Jürgen C, Wodrich, Harald, Pertl, Ursula, Karsten, Gabriele, Eliceiri, Brian P

“…Tumor cells are elusive targets for immunotherapy due to their heterogeneity and genetic instability. Here we describe a novel, oral DNA vaccine that targets…”
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In vivo Activity in a Catalytic Antibody-Prodrug System: Antibody Catalyzed Etoposide Prodrug Activation for Selective Chemotherapy by Shabat, Doron, Lode, Holger N., Pertl, Ursula, Reisfeld, Ralph A., Rader, Christoph, Lerner, Richard A., Barbas, Carlos F.

“…Effective chemotherapy remains a key issue for successful cancer treatment in general and neuroblastoma in particular. Here we report a chemotherapeutic…”
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Histone H2A-Mediated Transient Cytokine Gene Delivery Induces Efficient Antitumor Responses in Murine Neuroblastoma by Balicki, Danuta, Reisfeld, Ralph A., Pertl, Ursula, Beutler, Ernest, Lode, Holger N.

“…A major goal of cancer immunotherapy is the induction of a cell-mediated antitumor response in poorly immunogenic malignancies. We tested the hypothesis that…”
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Protective Immunity against Human Carcinoembryonic Antigen (CEA) Induced by an Oral DNA Vaccine in CEA-transgenic Mice by RONG XIANG, SILLETTI, Steve, LODE, Holger N, DOLMAN, Carrie S, RUEHLMANN, J. Michael, NIETHAMMER, Andreas G, PERTL, Ursula, GILLIES, Stephen D, PRIMUS, F. James, REISFELD, Ralph A

“…Peripheral T-cell tolerance toward human carcinoembryonic self-antigen (CEA) was broken in CEA-transgenic C57BL/6J mice by an oral CEA-based DNA vaccine. This…”
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Ralph A. Reisfeld, PhD: In Memoriam (1926–2020) by Allison, James P., Barker, Edward, Becker, Jürgen C., Bumol, Thomas F., Cheresh, David, Church, Bill, Ferrone, Soldano, Galloway, Darrell R., Giedlin, Martin, Gillies, Stephen, Handgretinger, Rupert, Harper, John R., Imai, Kohzoh, Kahan, Barry, Ladenstein, Ruth, Liao, Debbie, Lode, Holger N., Loibner, Hans, Luo, Yun-Ping, Mueller, Barbara M., Ng, AhKau, Niethammer, Andreas, Pellegrino, Michele, Pertl, Ursula, Quaranta, Vito, Russo, Carlo, Sabzevari, Helen, Schrappe, Martin, Schulz, Gregor, Sondel, Paul, Stahl, Andreas, Theophilopoulos, Argyrios, Varki, Nissi, Walker, Leslie, Wilson, Barry, Wrasidlo, Wolfgang, Wargalla-Plate, Ursula, Xiang, Rong, Yu, Alice, Zhou, He

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A DNA vaccine against VEGF receptor 2 prevents effective angiogenesis and inhibits tumor growth by Niethammer, A G, Xiang, R, Becker, J C, Wodrich, H, Pertl, U, Karsten, G, Eliceiri, B P, Reisfeld, R A

“…Tumor cells are elusive targets for immunotherapy due to their heterogeneity and genetic instability. Here we describe a novel, oral DNA vaccine that targets…”
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IFN-gamma-inducible protein-10 is essential for the generation of a protective tumor-specific CD8 T cell response induced by single-chain IL-12 gene therapy by Pertl, U, Luster, A D, Varki, N M, Homann, D, Gaedicke, G, Reisfeld, R A, Lode, H N

“…The successful induction of T cell-mediated protective immunity against poorly immunogenic malignancies remains a major challenge for cancer immunotherapy…”
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Immunotherapy with a posttranscriptionally modified DNA vaccine induces complete protection against metastatic neuroblastoma by Pertl, Ursula, Wodrich, Harald, Ruehlmann, J. Michael, Gillies, Stephen D., Lode, Holger N., Reisfeld, Ralph A.

“…The successful induction of a T-cell–mediated tumor-protective immunity against poorly immunogenic malignancies remains a major challenge for cancer…”
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MIG (CXCL9) chemokine gene therapy combines with antibody-cytokine fusion protein to suppress growth and dissemination of murine colon carcinoma by RUEHLMANN, J. Michael, RONG XIANG, NIETHAMMER, Andreas G, YI BA, PERTL, Ursula, DOLMAN, Carrie S, GILLIES, Stephen D, REISFELD, Ralph A

“…The induction of a CTL response capable of eradicating disseminated tumor metastases and the establishment of a persistent tumor-protective immunity remain…”
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Melanoma immunotherapy by targeted IL-2 depends on CD4(+) T-cell help mediated by CD40/CD40L interaction by Lode, H N, Xiang, R, Pertl, U, Förster, E, Schoenberger, S P, Gillies, S D, Reisfeld, R A

“…The induction of tumor-protective immunity against malignancies remains a major challenge in cancer immunotherapy. A novel, humanized…”
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Histone H2A-mediated transient cytokine gene delivery induced efficient antitumor responses in murine neuroblastoma by Balicki, Danuta, Reisfeld, Ralph A, Pertl, Ursula, Beutler, Ernest, Lode, Holger N

“…A major goal of cancer immunotherapy is the induction of a cell-mediated antitumor response in poorly immunogenic malignancies. We tested the hypothesis that…”
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IFN-{{gamma}}-Inducible Protein-10 Is Essential for the Generation of a Protective Tumor-Specific CD8 T Cell Response Induced by Single-Chain IL-12 Gene Therapy by Pertl, Ursula, Luster, Andrew D, Varki, Nissi M, Homann, Dirk, Gaedicke, Gerhard, Reisfeld, Ralph A, Lode, Holger N

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What to do with targeted IL-2 by Lode, H N, Xiang, R, Perri, P, Pertl, U, Lode, A, Gillies, S D, Reisfeld, R A

“…A common strategy in immunotherapy of cancer is the induction of an increased immunogenicity of syngeneic malignancies. A novel approach to achieve this goal…”
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Treatment of children with relapsed soft tissue sarcoma: Report of the German CESS/CWS REZ 91 Trial by Klingebiel, Thomas, Pertl, Ursula, Hess, Clemens F., Jürgens, Herbert, Koscielniak, Ewa, Pötter, Richard, van Heek-Romanowski, Ralf, Rossi, Rainer, Schött, Christian, Spaar, Hans-Joachim, Willnow, Ullrich, Treuner, Jörn

“…Background The present study was performed to evaluate the possibilities of relapse treatment in patients heavily pretreated for a soft tissue sarcoma…”
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