Search Results - "PERSANI, Luca"

Central Hypothyroidism: Pathogenic, Diagnostic, and Therapeutic Challenges by Persani, Luca

“…Context: Central hypothyroidism (CH) is a particular hypothyroid condition due to an insufficient stimulation by TSH of an otherwise normal thyroid gland. This…”
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The fundamental role of bone morphogenetic protein 15 in ovarian function and its involvement in female fertility disorders by Persani, Luca, Rossetti, Raffaella, Di Pasquale, Elisa, Cacciatore, Chiara, Fabre, Stéphane

“…A large number of studies have contributed to understanding the general mechanisms driving ovarian folliculogenesis in humans and show a complex endocrine…”
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Genes involved in human premature ovarian failure by Persani, Luca, Rossetti, Raffaella, Cacciatore, Chiara

“…Premature ovarian failure (POF) is an ovarian defect characterized by the premature depletion of ovarian follicles before the age of 40 years, representing one…”
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Premature ovarian failure by Beck-Peccoz, Paolo, Persani, Luca

“…Premature ovarian failure (POF) is a primary ovarian defect characterized by absent menarche (primary amenorrhea) or premature depletion of ovarian follicles…”
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Primary Adrenal Insufficiency During Lenvatinib or Vandetanib and Improvement of Fatigue After Cortisone Acetate Therapy by Colombo, Carla, De Leo, Simone, Di Stefano, Marta, Vannucchi, Guia, Persani, Luca, Fugazzola, Laura

“…Two tyrosine kinase inhibitors (TKIs), lenvatinib and vandetanib, are often used to treat advanced radioiodine-refractory differentiated thyroid cancer (RAI-R…”
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Genetics and management of congenital hypothyroidism by Persani, Luca, Rurale, Giuditta, de Filippis, Tiziana, Galazzi, Elena, Muzza, Marina, Fugazzola, Laura

“…Several evidences support a relevant genetic origin for Congenital Hypothyroidism (CH), however familial forms are uncommon. CH can be due to morphogenetic or…”
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Short-Term Exposure Effects of the Environmental Endocrine Disruptor Benzo(a)Pyrene on Thyroid Axis Function in Zebrafish by Rurale, Giuditta, Gentile, Ilaria, Carbonero, Camilla, Persani, Luca, Marelli, Federica

“…Benzo(a)Pyrene (BaP) is one of the most widespread polycyclic aromatic hydrocarbons (PAHs) with endocrine disrupting properties and carcinogenic effects. In…”
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Signaling by internalized G-protein-coupled receptors by Calebiro, Davide, Nikolaev, Viacheslav O, Persani, Luca, Lohse, Martin J

“…G-protein-coupled receptors (GPCRs) are cell surface receptors and are generally assumed to signal to second messengers such as cyclic AMP (cAMP) exclusively…”
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The diagnosis and management of central hypothyroidism in 2018 by Persani, Luca, Cangiano, Biagio, Bonomi, Marco

“…Central hypothyrodism (CeH) is a hypothyroid state caused by an insufficient stimulation by thyrotropin (TSH) of an otherwise normal thyroid gland. Several…”
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The spectrum of thyroid function tests during hospitalization for SARS COV-2 infection by Campi, Irene, Bulgarelli, Ilaria, Dubini, Antonella, Perego, Giovanni Battista, Tortorici, Elena, Torlasco, Camilla, Torresani, Erminio, Rocco, Lorenzo, Persani, Luca, Fugazzola, Laura

“…Objective Alterations in thyroid function tests (TFTs) have been recorded during SARS-CoV-2 infection as associated to either a destructive thyroiditis or a…”
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Vitamin D Status and SARS-CoV-2 Infection and COVID-19 Clinical Outcomes by Chiodini, Iacopo, Gatti, Davide, Soranna, Davide, Merlotti, Daniela, Mingiano, Christian, Fassio, Angelo, Adami, Giovanni, Falchetti, Alberto, Eller-Vainicher, Cristina, Rossini, Maurizio, Persani, Luca, Zambon, Antonella, Gennari, Luigi

“…Several studies suggest an association between serum 25-hydroxyvitamin D (25OHD) and the outcomes of Severe Acute Respiratory Syndrome Corona-Virus-2…”
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PI3K/Akt/mTOR signaling in medullary thyroid cancer: a promising molecular target for cancer therapy by Manfredi, Gloria Irene, Dicitore, Alessandra, Gaudenzi, Germano, Caraglia, Michele, Persani, Luca, Vitale, Giovanni

“…The phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway is a central hub for the regulation of cell proliferation, apoptosis,…”
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Vitamin D and COVID-19 severity and related mortality: a prospective study in Italy by Campi, Irene, Gennari, Luigi, Merlotti, Daniela, Mingiano, Christian, Frosali, Alessandro, Giovanelli, Luca, Torlasco, Camilla, Pengo, Martino F, Heilbron, Francesca, Soranna, Davide, Zambon, Antonella, Di Stefano, Marta, Aresta, Carmen, Bonomi, Marco, Cangiano, Biagio, Favero, Vittoria, Fatti, Letizia, Perego, Giovanni Battista, Chiodini, Iacopo, Parati, Gianfranco, Persani, Luca

“…Abstract Background Vitamin D deficiency has been suggested to favor a poorer outcome of Coronavirus disease-19 (COVID-19). We aimed to assess if…”
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Advances in the Molecular Pathophysiology, Genetics, and Treatment of Primary Ovarian Insufficiency by Huhtaniemi, Ilpo, Hovatta, Outi, La Marca, Antonio, Livera, Gabriel, Monniaux, Danielle, Persani, Luca, Heddar, Abdelkader, Jarzabek, Katarzyna, Laisk-Podar, Triin, Salumets, Andres, Tapanainen, Juha S., Veitia, Reiner A., Visser, Jenny A., Wieacker, Peter, Wolczynski, Slawomir, Misrahi, Micheline

“…Primary ovarian insufficiency (POI) affects ∼1% of women before 40 years of age. The recent leap in genetic knowledge obtained by next generation sequencing…”
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FAM83B is involved in thyroid cancer cell differentiation and migration by Cirello, Valentina, Grassi, Elisa Stellaria, Pogliaghi, Gabriele, Ghiandai, Viola, Ermellino, Laura, Muzza, Marina, Gazzano, Giacomo, Persani, Luca, Colombo, Carla, Fugazzola, Laura

“…FAM83B has been recently identified as an oncogene, but its role in thyroid cancers (TC) is still unclear. We examined the expression of FAM83B and its…”
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The multiple genetic causes of central hypothyroidism by Persani, Luca, MD, PhD, Bonomi, Marco, MD

“…An insufficient stimulation by thyrotropin (TSH) of an otherwise normal thyroid gland represents the cause of Central Hypothyrodism (CeH). CeH is about…”
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New genetics in congenital hypothyroidism by Stoupa, Athanasia, Kariyawasam, Dulanjalee, Muzza, Marina, de Filippis, Tiziana, Fugazzola, Laura, Polak, Michel, Persani, Luca, Carré, Aurore

“…Introduction Congenital hypothyroidism (CH) is the most frequent neonatal endocrine disorder and one of the most common preventable forms of mental retardation…”
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Luteinizing Hormone Signaling in Preovulatory Follicles Involves Early Activation of the Epidermal Growth Factor Receptor Pathway by Panigone, Sara, Hsieh, Minnie, Fu, Maoyong, Persani, Luca, Conti, Marco

“…LH activates a cascade of signaling events that are propagated throughout the ovarian preovulatory follicle to promote ovulation of a mature egg. Critical to…”
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Lenvatinib as first-line treatment for advanced thyroid cancer: long progression-free survival by De Leo, Simone, Di Stefano, Marta, Persani, Luca, Fugazzola, Laura, Colombo, Carla

“…Purpose Lenvatinib (LEN) has been approved for the treatment of patients with progressive radioiodine-refractory differentiated thyroid cancer (RAI-R DTC)…”
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ENDO-ERN expert opinion on the differential diagnosis of pubertal delay by Persani, Luca, Bonomi, Marco, Cools, Martine, Dattani, Mehul, Dunkel, Leo, Gravholt, Claus H., Juul, Anders

“…The differential diagnoses of pubertal delay include hypergonadotropic hypogonadism and congenital hypogonadotropic hypogonadism (CHH), as well as…”
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