Search Results - "PERREN, Aurel"
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Overview of the 2022 WHO Classification of Parathyroid Tumors
Published in Endocrine pathology (01-03-2022)“…The 2022 WHO classification reflects increases in the knowledge of the underlying pathogenesis of parathyroid disease. In addition to the classic…”
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The molecular characteristics of high-grade gastroenteropancreatic neuroendocrine neoplasms
Published in Endocrine-related cancer (01-01-2022)“…High-grade (HG) gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) are rare but have a very poor prognosis and represent a severely understudied class…”
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Overview of the 2022 WHO Classification of Familial Endocrine Tumor Syndromes
Published in Endocrine pathology (01-03-2022)“…This review of the familial tumor syndromes involving the endocrine organs is focused on discussing the main updates on the upcoming fifth edition of the WHO…”
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The Gastroenteropancreatic Neuroendocrine Cell System and Its Tumors: The WHO Classification
Published in Annals of the New York Academy of Sciences (01-04-2004)“…: Although well established in medical terminology, the term carcinoid is no longer adequate to cover the entire morphological and biological spectrum of…”
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Autophagy Inhibition Improves Sunitinib Efficacy in Pancreatic Neuroendocrine Tumors via a Lysosome-dependent Mechanism
Published in Molecular cancer therapeutics (01-11-2017)“…Increasing the efficacy of approved systemic treatments in metastasized pancreatic neuroendocrine tumors (PanNET) is an unmet medical need. The antiangiogenic…”
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Evidence of a common cell origin in a case of pancreatic mixed intraductal papillary mucinous neoplasm–neuroendocrine tumor
Published in Virchows Archiv : an international journal of pathology (01-06-2021)“…Recently, the term mixed neuroendocrine non-neuroendocrine neoplasms (MiNEN) has been proposed as an umbrella definition covering different possible…”
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Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression
Published in Communications biology (07-12-2020)“…Recent data suggest that Pancreatic Neuroendocrine Tumours (PanNETs) originate from α- or β-cells of the islets of Langerhans. The majority of PanNETs are…”
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Surgery with Radical Intent: Is There an Indication for G3 Neuroendocrine Neoplasms?
Published in Annals of surgical oncology (01-05-2020)“…Background While platinum-based chemotherapy represents the standard treatment for advanced grade 3 (G3) neuroendocrine neoplasms (NENs) according to the…”
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Somatostatin receptor subtype 2A immunohistochemistry using a new monoclonal antibody selects tumors suitable for in vivo somatostatin receptor targeting
Published in The American journal of surgical pathology (01-02-2012)“…High overexpression of somatostatin receptors in neuroendocrine tumors allows imaging and radiotherapy with radiolabeled somatostatin analogues. To ascertain…”
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Comprehensive MicroRNA expression profiling identifies novel markers in follicular variant of papillary thyroid carcinoma
Published in Thyroid (New York, N.Y.) (01-11-2013)“…Follicular variant of papillary thyroid carcinoma (FVPTC) shares features of papillary (PTC) and follicular (FTC) thyroid carcinomas on a clinical,…”
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Tall cell papillary thyroid carcinoma: new diagnostic criteria and mutations in BRAF and TERT
Published in Endocrine-related cancer (01-06-2015)“…The tall cell (TC) variant of papillary thyroid carcinoma (PTC) has an unfavorable prognosis. The diagnostic criteria remain inconsistent, and the role of a…”
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Genes and proteins of the alternative steroid backdoor pathway for dihydrotestosterone synthesis are expressed in the human ovary and seem enhanced in the polycystic ovary syndrome
Published in Molecular and cellular endocrinology (05-02-2017)“…Recently, dihydrotestosterone biosynthesis through the backdoor pathway has been implicated for the human testis in addition to the classic pathway for…”
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Müller matrix polarimetry for pancreatic tissue characterization
Published in Scientific reports (29-09-2023)“…Polarimetry is an optical characterization technique capable of analyzing the polarization state of light reflected by materials and biological samples. In…”
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Intraductal papillary neoplasms of the bile duct: stepwise progression to carcinoma involves common molecular pathways
Published in Modern pathology (01-01-2014)“…Intraductal papillary neoplasms of the bile duct are still poorly characterized regarding (1) their molecular alterations during the development to invasive…”
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Increased Number of Islet-Associated Macrophages in Type 2 Diabetes
Published in Diabetes (New York, N.Y.) (01-09-2007)“…Increased Number of Islet-Associated Macrophages in Type 2 Diabetes Jan A. Ehses 1 , Aurel Perren 2 , Elisabeth Eppler 3 , Pascale Ribaux 4 , John A…”
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MicroRNA profile of poorly differentiated thyroid carcinomas: new diagnostic and prognostic insights
Published in Journal of molecular endocrinology (01-04-2014)“…The diagnosis of conventional and oncocytic poorly differentiated (oPD) thyroid carcinomas is difficult. The aim of this study is to characterise their largely…”
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Candidate protein biomarkers in pancreatic neuroendocrine neoplasms grade 3
Published in Scientific reports (30-06-2020)“…Pancreatic neuroendocrine neoplasms (PanNENs) are rare tumours that compose 1–2% of all pancreatic tumours. Patients with metastatic grade 3 neoplasia are…”
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RET gene rearrangements occur in a subset of pancreatic acinar cell carcinomas
Published in Modern pathology (01-04-2020)“…Pancreatic acinar cell carcinoma is relatively rare (1 to 2% of pancreatic malignancies) but may be under-recognized. In contrast to pancreatic ductal…”
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The Problem of High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms
Published in Endocrinology and metabolism clinics of North America (01-09-2018)“…High-grade gastroenteropancreatic neuroendocrine neoplasms are well-differentiated neuroendocrine tumors or poorly differentiated small/large cell…”
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