Search Results - "PEREIRA, Stephen P"
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1
Molecular Pathogenesis of Cholangiocarcinoma
Published in BMC cancer (28-02-2019)“…Cholangiocarcinomas are a heterogeneous group of malignancies arising from a number of cells of origin along the biliary tree. Although most cases in Western…”
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2
The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines
Published in Gut (01-09-2018)“…Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an autoimmune liver disease in which a cycle of immune mediated biliary…”
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3
Cisplatin plus Gemcitabine versus Gemcitabine for Biliary Tract Cancer
Published in The New England journal of medicine (08-04-2010)“…In this randomized trial comparing cisplatin plus gemcitabine with gemcitabine alone for the treatment of biliary tract cancer, overall survival and…”
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4
Serum C-reactive protein, procalcitonin, and lactate dehydrogenase for the diagnosis of pancreatic necrosis
Published in Cochrane database of systematic reviews (21-04-2017)“…The treatment of people with pancreatic necrosis differs from that of people with oedematous pancreatitis. It is important to know the diagnostic accuracy of…”
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5
Role of gastrointestinal endoscopy in the screening of digestive tract cancers in Europe: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement
Published in Endoscopy (01-04-2020)“…In Europe at present, but also in 2040, 1 in 3 cancer-related deaths are expected to be caused by digestive cancers. Endoscopic technologies enable diagnosis,…”
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6
Can we screen for pancreatic cancer? Identifying a sub-population of patients at high risk of subsequent diagnosis using machine learning techniques applied to primary care data
Published in PloS one (02-06-2021)“…Pancreatic cancer (PC) represents a substantial public health burden. Pancreatic cancer patients have very low survival due to the difficulty of identifying…”
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7
Serum amylase and lipase and urinary trypsinogen and amylase for diagnosis of acute pancreatitis
Published in Cochrane database of systematic reviews (21-04-2017)“…The treatment of people with acute abdominal pain differs if they have acute pancreatitis. It is important to know the diagnostic accuracy of serum amylase,…”
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8
Biomodulatory approaches to photodynamic therapy for solid tumors
Published in Cancer letters (29-12-2012)“…Highlights ► Photodynamic therapy (PDT) uses a combination of photosensitizer and light to treat various cancers and precancers. ► Efforts to make PDT more…”
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9
Systematic review of novel ablative methods in locally advanced pancreatic cancer
Published in World journal of gastroenterology : WJG (07-03-2014)“…Unresectable locally advanced pancreatic cancer with or without metastatic disease is associated with a very poor prognosis.Current standard therapy is limited…”
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10
Diagnostic and prognostic biomarkers in cholangiocarcinoma
Published in Liver international (01-05-2019)“…The high mortality rate of cholangiocarcinoma (CCA) is due, in part, to the lack of non‐invasive approaches able to accurately detect this silent tumour at…”
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11
A combination of urinary biomarker panel and PancRISK score for earlier detection of pancreatic cancer: A case-control study
Published in PLoS medicine (10-12-2020)“…Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with around 9% of patients surviving >5 years. Asymptomatic in its initial stages,…”
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12
Identification of a Three-Biomarker Panel in Urine for Early Detection of Pancreatic Adenocarcinoma
Published in Clinical cancer research (01-08-2015)“…Noninvasive biomarkers for early detection of pancreatic ductal adenocarcinoma (PDAC) are currently not available. Here, we aimed to identify a set of urine…”
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13
Pyruvate Kinase M2 and Lactate Dehydrogenase A Are Overexpressed in Pancreatic Cancer and Correlate with Poor Outcome
Published in PloS one (18-03-2016)“…Pancreatic cancer has a 5-year survival rate of less than 4%. Despite advances in diagnostic technology, pancreatic cancer continues to be diagnosed at a late…”
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14
Evaluation of urinary C-reactive protein as an early detection biomarker for pancreatic ductal adenocarcinoma
Published in Frontiers in oncology (06-09-2024)“…Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer-related death worldwide. Up to now, no specific screening or diagnostic tests…”
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15
Biliary Strictures and Cholangiocarcinoma - Untangling a Diagnostic Conundrum
Published in Frontiers in oncology (30-09-2021)“…Cholangiocarcinoma is an uncommon and highly aggressive biliary tract malignancy with few manifestations until late disease stages. Diagnosis is currently…”
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16
Presentation and Management of Post-treatment Relapse in Autoimmune Pancreatitis/Immunoglobulin G4-Associated Cholangitis
Published in Clinical gastroenterology and hepatology (01-10-2009)“…Background & Aims Autoimmune pancreatitis (AIP) is a multisystem disorder that often has extrapancreatic manifestations such as immunoglobulin G4–associated…”
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17
Evidence of Altered Glycosylation of Serum Proteins Prior to Pancreatic Cancer Diagnosis
Published in International journal of molecular sciences (09-12-2017)“…Biomarkers for the early detection of pancreatic cancer are urgently needed. The aim of this pilot study was to evaluate changes in serum -glycoproteins and…”
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18
Blood levels of adiponectin and IL-1Ra distinguish type 3c from type 2 diabetes: Implications for earlier pancreatic cancer detection in new-onset diabetes
Published in EBioMedicine (01-01-2022)“…Screening for pancreatic ductal adenocarcinoma (PDAC) in populations at high risk is recommended. Individuals with new-onset type 2 diabetes mellitus (NOD) are…”
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Serum biomarker-based early detection of pancreatic ductal adenocarcinomas with ensemble learning
Published in Communications medicine (20-01-2023)“…Background Earlier detection of pancreatic ductal adenocarcinoma (PDAC) is key to improving patient outcomes, as it is mostly detected at advanced stages which…”
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Paediatric pancreaticobiliary endoscopy: a 21-year experience from a tertiary hepatobiliary centre and systematic literature review
Published in BMC pediatrics (09-02-2018)“…In adults ERCP and endoscopic ultrasound (EUS) are standard methods of evaluating and treating many hepatopancreaticobiliary (HPB) conditions. HPB disease is…”
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