Search Results - "PEPPER, C"

Worldwide experience with a totally subcutaneous implantable defibrillator: early results from the EFFORTLESS S-ICD Registry by Lambiase, Pier D, Barr, Craig, Theuns, Dominic A M J, Knops, Reinoud, Neuzil, Petr, Johansen, Jens Brock, Hood, Margaret, Pedersen, Susanne, Kääb, Stefan, Murgatroyd, Francis, Reeve, Helen L, Carter, Nathan, Boersma, Lucas

“…The totally subcutaneous implantable-defibrillator (S-ICD) is a new alternative to the conventional transvenous ICD system to minimize intravascular lead…”
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A prospective cohort study exploring the impact of tonsillectomy on feeding difficulties in children by Walsh, M. E., Retzler, R., Huang, J., Daglish, A., Tweedie, D., Pepper, C.

“…Objectives Paediatric feeding difficulties are common, affecting up to 25% of otherwise healthy children, symptoms include food refusal, gagging, choking, and…”
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P1266: FLOW CYTOMETRY COMBINED WITH SYSTEMS BIOLOGY ENABLES RATIONAL TARGETING OF NFKB IN DLBCL by Jayawant, E., Pepper, A., Pepper, C., Mitchell, S.

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Two-dimensional strain imaging: A new echocardiographic advance with research and clinical applications by Artis, N.J, Oxborough, D.L, Williams, G, Pepper, C.B, Tan, L.B

“…Abstract Over the past two decades the quest for quantitative evaluation of left ventricular function and regional wall motion has escalated, allowing several…”
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The enzymatic activities of CD38 enhance CLL growth and trafficking: implications for therapeutic targeting by Vaisitti, T, Audrito, V, Serra, S, Buonincontri, R, Sociali, G, Mannino, E, Pagnani, A, Zucchetto, A, Tissino, E, Vitale, C, Coscia, M, Usai, C, Pepper, C, Gattei, V, Bruzzone, S, Deaglio, S

“…The ecto-enzyme CD38 is gaining momentum as a novel therapeutic target for patients with hematological malignancies, with several anti-CD38 monoclonal…”
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Telomere length predicts progression and overall survival in chronic lymphocytic leukemia: data from the UK LRF CLL4 trial by Strefford, J C, Kadalayil, L, Forster, J, Rose-Zerilli, M J J, Parker, A, Lin, T T, Heppel, N, Norris, K, Gardiner, A, Davies, Z, Gonzalez de Castro, D, Else, M, Steele, A J, Parker, H, Stankovic, T, Pepper, C, Fegan, C, Baird, D, Collins, A, Catovsky, D, Oscier, D G

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CD38 increases CXCL12-mediated signals and homing of chronic lymphocytic leukemia cells by Vaisitti, T, Aydin, S, Rossi, D, Cottino, F, Bergui, L, D'Arena, G, Bonello, L, Horenstein, A L, Brennan, P, Pepper, C, Gaidano, G, Malavasi, F, Deaglio, S

“…Homing of chronic lymphocytic leukemia (CLL) cells to sites favoring growth, a critical step in disease progression, is principally coordinated by the…”
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Cost-effectiveness of radiofrequency catheter ablation for the treatment of atrial fibrillation in the United Kingdom by McKenna, C, Palmer, S, Rodgers, M, Chambers, D, Hawkins, N, Golder, S, Van Hout, S, Pepper, C, Todd, D, Woolacott, N

“…To assess the cost-effectiveness of radiofrequency catheter ablation (RFCA) compared with anti-arrhythmic drug (AAD) therapy for the treatment of atrial…”
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The cyclin-dependent kinase inhibitor SNS-032 has single agent activity in AML cells and is highly synergistic with cytarabine by Walsby, E, Lazenby, M, Pepper, C, Burnett, A K

“…SNS-032 (BMS-387032) is a selective cyclin-dependent kinase (CDK) inhibitor. In this study, we evaluated its effects on primary acute myeloid leukemia (AML)…”
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Telomere fusion threshold identifies a poor prognostic subset of breast cancer patients by Simpson, K., Jones, R.E., Grimstead, J.W., Hills, R., Pepper, C., Baird, D.M.

“…Telomere dysfunction and fusion can drive genomic instability and clonal evolution in human tumours, including breast cancer. Telomere length is a critical…”
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P1252: PREDICTING THE RESPONSE OF DLBCL CELLS TO BH3‐MIMETICS USING SYSTEMS BIOLOGY by Cloete, I., Smith, V., Jackson, R., Pepper, A., Pepper, C., Dyer, M., Mitchell, S.

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PB1788: LOW EXPRESSION OF C‐TYPE LECTIN‐LIKE MOLECULE‐1 AND REDUCED OXIDATIVE STRESS DEFINE A SUBSET OF ACUTE MYELOID LEUKAEMIA CELLS WITH ‘STEM‐LIKE’ PROPERTIES by Sharp, K., Ladikou, E., Burley, T., Kennedy, E., Pepper, A., Pepper, C.

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Phenotypic heterogeneity in IGHV-mutated CLL patients has prognostic impact and identifies a subset with increased sensitivity to BTK and PI3Kδ inhibition by Pepper, C, Buggins, A G S, Jones, C H, Walsby, E J, Forconi, F, Pratt, G, Devereux, S, Stevenson, F K, Fegan, C

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Prospective study of the risk of not using prophylactic antibiotics in nasal packing for epistaxis by Pepper, C, Lo, S, Toma, A

“…There is wide variation in UK prescribing practice regarding prophylactic antibiotics for nasal packing in spontaneous epistaxis. There are few published cases…”
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Paediatric tracheostomy tubes: recent developments and our current practice by Tweedie, D J, Cooke, J, Stephenson, K A, Gupta, S L, Pepper, C M, Elloy, M D, Cochrane, L A, Wyatt, M E

“…A variety of paediatric tracheostomy tubes are available. This article reviews the tubes in current use at Great Ormond Street Hospital for Children and…”
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Effects of the aurora kinase inhibitors AZD1152-HQPA and ZM447439 on growth arrest and polyploidy in acute myeloid leukemia cell lines and primary blasts by Walsby, Elisabeth, Walsh, Val, Pepper, Chris, Burnett, Alan, Mills, Ken

“…1 Department of Haematology, School of Medicine, Cardiff University, Cardiff, South Glamorgan and 2 Center for Cancer Research and Cell Biology, Queens…”
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P418: MODELLING AND TARGETING ACUTE MYELOID LEUKAEMIA CELLS IN THE BONE MARROW PROTECTIVE NICHE by Ladikou, E. E., Sharp, K., Burley, T. A., Kennedy, E., Chevassut, T., Pepper, C., Pepper, A. G.

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Investigating the impact of telomere dysfunction on the cancer genome by Escudero, L, Fegan, C, Pepper, C, Ashelford, K, Norris, K, Cleal, K, Liddiard, K, Baird, D.M

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Curative catheter ablation in atrial fibrillation and typical atrial flutter: systematic review and economic evaluation by Rodgers, M, McKenna, C, Palmer, S, Chambers, D, Van Hout, S, Golder, S, Pepper, C, Todd, D, Woolacott, N

“…To determine the safety, clinical effectiveness and cost-effectiveness of radio frequency catheter ablation (RCFA) for the curative treatment of atrial…”
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Extreme telomere erosion in ATM-mutated and 11q-deleted CLL patients is independent of disease stage by Britt-Compton, B, Lin, T T, Ahmed, G, Weston, V, Jones, R E, Fegan, C, Oscier, D G, Stankovic, T, Pepper, C, Baird, D M

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