Search Results - "PENIN, F"

Nonstructural protein 3-4A: the Swiss army knife of hepatitis C virus by Morikawa, K., Lange, C. M., Gouttenoire, J., Meylan, E., Brass, V., Penin, F., Moradpour, D.

“…Hepatitis C virus (HCV) nonstructural protein 3‐4A (NS3‐4A) is a complex composed of NS3 and its cofactor NS4A. It harbours serine protease as well as…”
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Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes by SIMMONDS, Peter, BUKH, Jens, MIZOKAMI, Masashi, MURPHY, Donald G, OKAMOTO, Hiroaki, PAWLOTSKY, Jean-Michel, PENIN, Francois, SABLON, Erwin, SHIN-I, Tadasu, STUYVER, Lieven J, THIEL, Heinz-Jürgen, VIAZOV, Sergei, COMBET, Christophe, WEINER, Amy J, WIDELL, Anders, DELEAGE, Gilbert, ENOMOTO, Nobuyuki, FEINSTONE, Stephen, HALFON, Phillippe, INCHAUSPE, Geneviève, KUIKEN, Carla, MAERTENS, Geert

“…International standardization and coordination of the nomenclature of variants of hepatitis C virus (HCV) is increasingly needed as more is discovered about…”
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Hepatitis C virus NS2 is a protease stimulated by cofactor domains in NS3 by Schregel, V, Jacobi, S, Penin, F, Tautz, N

“…Chronic infection with hepatitis C virus (HCV) affects 130 million people worldwide and is a major cause of liver cirrhosis and liver cancer. After translation…”
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Hepatitis C virus infection protein network by de Chassey, B, Navratil, V, Tafforeau, L, Hiet, M S, Aublin‐Gex, A, Agaugué, S, Meiffren, G, Pradezynski, F, Faria, B F, Chantier, T, Le Breton, M, Pellet, J, Davoust, N, Mangeot, P E, Chaboud, A, Penin, F, Jacob, Y, Vidalain, P O, Vidal, M, André, P, Rabourdin‐Combe, C, Lotteau, V

“…A proteome‐wide mapping of interactions between hepatitis C virus (HCV) and human proteins was performed to provide a comprehensive view of the cellular…”
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From Structure to Function: New Insights into Hepatitis C Virus RNA Replication by Appel, Nicole, Schaller, Torsten, Penin, Francois, Bartenschlager, Ralf

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Structural biology of hepatitis C virus by Penin, François, Dubuisson, Jean, Rey, Felix A., Moradpour, Darius, Pawlotsky, Jean‐Michel

“…Hepatitis C virus (HCV) causes acute and chronic liver disease in humans, including chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Studies of this…”
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Viral and Cellular Determinants of Hepatitis C Virus RNA Replication in Cell Culture by Lohmann, Volker, Hoffmann, Sandra, Herian, Ulrike, Penin, Francois, Bartenschlager, Ralf

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An Interplay between Hypervariable Region 1 of the Hepatitis C Virus E2 Glycoprotein, the Scavenger Receptor BI, and High-Density Lipoprotein Promotes both Enhancement of Infection and Protection against Neutralizing Antibodies by BARTOSCH, Birke, VERNEY, Géraldine, DREUX, Marlène, DONOT, Peggy, MORICE, Yoann, PENIN, Francois, PAWLOTSKY, Jean-Michel, LAVILLETTE, Dimitri, COSSET, Francois-Loïc

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Structure and Function of the Membrane Anchor Domain of Hepatitis C Virus Nonstructural Protein 5A by Penin, François, Brass, Volker, Appel, Nicole, Ramboarina, Stephanie, Montserret, Roland, Ficheux, Damien, Blum, Hubert E., Bartenschlager, Ralf, Moradpour, Darius

“…Hepatitis C virus (HCV) nonstructural protein 5A (NS5A) is a membrane-associated, essential component of the viral replication complex. Here, we report the…”
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An Amino-terminal Amphipathic α-Helix Mediates Membrane Association of the Hepatitis C Virus Nonstructural Protein 5A by Brass, Volker, Bieck, Elke, Montserret, Roland, Wölk, Benno, Hellings, Jan Albert, Blum, Hubert E., Penin, François, Moradpour, Darius

“…Hepatitis C virus (HCV) nonstructural protein 5A (NS5A), a phosphoprotein of unknown function, is believed to be a component of a membrane-associated viral…”
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P0683 : Hepatitis C virus NS3-4A protease targets the host factor BNIP1 at a non-canonical cleavage site by Thi Lan Tran, H, Morikawa, K, Penin, F, Quadroni, M, Gouttenoire, J, Moradpour, D

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Hepatitis C Virus Core Protein Is a Dimeric Alpha-Helical Protein Exhibiting Membrane Protein Features by BOULANT, Steeve, VANBELLE, Christophe, EBEL, Christine, PENIN, Francois, LAVERGNE, Jean-Pierre

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Interaction of hepatitis C virus proteins with host cell membranes and lipids by Dubuisson, Jean, Penin, François, Moradpour, Darius

“…For replication, viruses depend on specific components and energy supplies from the host cell. The main steps in the lifecycle of positive-strand RNA viruses…”
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Quantitative Analysis of Backbone Dynamics in a Crystalline Protein from Nitrogen-15 Spin−Lattice Relaxation by Giraud, Nicolas, Blackledge, Martin, Goldman, Maurice, Böckmann, Anja, Lesage, Anne, Penin, François, Emsley, Lyndon

“…A detailed analysis of nitrogen-15 longitudinal relaxation times in microcrystalline proteins is presented. A theoretical model to quantitatively interpret…”
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Hepatitis C Virus Glycoproteins Mediate Low pH-dependent Membrane Fusion with Liposomes by Lavillette, Dimitri, Bartosch, Birke, Nourrisson, Delphine, Verney, Géraldine, Cosset, François-Loïc, Penin, François, Pécheur, Eve-Isabelle

“…It has been suggested that the hepatitis C virus (HCV) infects host cells through a pH-dependent internalization mechanism, but the steps leading from virus…”
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Membrane Association of the RNA-Dependent RNA Polymerase Is Essential for Hepatitis C Virus RNA Replication by MORADPOUR, Darius, BRASS, Volker, BIECK, Elke, FRIEBE, Peter, GOSERT, Rainer, BLUM, Hubert E, BARTENSCHLAGER, Ralf, PENIN, Francois, LOHMANN, Volker

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Evidence of Viral Replication in Circulating Dendritic Cells during Hepatitis C Virus Infection by Goutagny, Nadège, Fatmi, Ahmed, Ledinghen, Victor De, Penin, François, Couzigou, Patrice, Inchauspé, Geneviève, Bain, Christine

“…The existence of extrahepatic sites of hepatitis C virus (HCV) replication has been proposed as a mechanism responsible for the poor antiviral immune response…”
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Subcellular Localization and Topology of the p7 Polypeptide of Hepatitis C Virus by Carrere-Kremer, S, Montpellier-Pala, C, Cocquerel, L, Wychowski, C, Penin, F, Dubuisson, J

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Site-Specific Backbone Dynamics from a Crystalline Protein by Solid-State NMR Spectroscopy by Giraud, Nicolas, Böckmann, Anja, Lesage, Anne, Penin, François, Blackledge, Martin, Emsley, Lyndon

“…Site-specific nitrogen-15 longitudinal relaxation rates are measured for the microcrystalline dimeric form of the protein Crh using multidimensional…”
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Frequent compartmentalization of hepatitis C virus variants in circulating B cells and monocytes by Ducoulombier, Delphine, Roque‐Afonso, Anne‐Marie, Di Liberto, Gaëtana, Penin, François, Kara, Rachid, Richard, Yolande, Dussaix, Elisabeth, Féray, Cyrille

“…Differences in the composition of the hepatitis C virus (HCV) quasispecies between plasma and blood mononuclear cells (BMC) strongly suggest that BMCs support…”
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