Search Results - "PENFOLD, PHILIP L."

Immunological and Aetiological Aspects of Macular Degeneration by Penfold, Philip L, Madigan, Michele C, Gillies, Mark C, Provis, Jan M

“…Aetiological and immunological aspects of AMD, a leading cause of blindness in Western countries, have been reviewed. Developmental studies suggest that…”
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Development of the Human Retinal Vasculature: Cellular Relations and VEGF Expression by PROVIS, JAN M, LEECH, JESSICA, DIAZ, CLAUDIA M, PENFOLD, PHILIP L, STONE, JONATHON, KESHET, ELI

“…We have investigated the relationships of the cellular constituents of the retinal vasculature—astrocytes, microglia and pericytes—to the differentiating…”
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The Human Hyaloid System: Cellular Phenotypes and Inter-relationships by ZHU, MEIDONG, PROVIS, JAN M, PENFOLD, PHILIP L

“…We have investigated the expression of leucocyte markers, phenotypic characteristics and cellular relationships of the normal human fetal hyaloid vasculature…”
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Anatomy and development of the macula: specialisation and the vulnerability to macular degeneration by Provis, Jan M., Penfold, Philip L., Cornish, Elisa E., Sandercoe, Trent M., Madigan, Michele C.

“…The central retina in primates is adapted for high acuity vision. The most significant adaptations to neural retina in this respect are: 1. The very high…”
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Modulation of Permeability and Adhesion Molecule Expression by Human Choroidal Endothelial Cells by Penfold, Philip L, Wen, Li, Madigan, Michele C, King, Nicholas J. C, Provis, Jan M

“…The therapeutic potential of TA, an anti-inflammatory glucocorticoid, for the treatment of exudative retinopathy has been examined in several independent…”
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Cone degeneration in aging and age-related macular degeneration by Shelley, Elizabeth J, Madigan, Michele C, Natoli, Riccardo, Penfold, Philip L, Provis, Jan M

“…To examine the morphological features of macular photoreceptors in histologically normal retina from normal donor eyes and eyes with age-related macular…”
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Effects of triamcinolone acetonide on microglial morphology and quantitative expression of MHC-II in exudative age-related macular degeneration by Penfold, Philip L, Wong, James G, Gyory, Joseph, Billson, Francis A

“…ABSTRACT Animal models, in vitro assays and pilot clinical studies suggest that intravitreal triamcinolone acetonide may be useful in the treatment of…”
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Exudative macular degeneration and intravitreal triamcinolone: 18 month follow up by Challa, Jagannadh K, Gillies, Mark C, Penfold, Philip L, Gyory, Joseph F, Hunyor, Alexander BL, Billson, Francis A

“…Purpose: To evaluate the safety and efficacy of intravitreal triamcinolone after 18 months of follow up in patients with age‐related macular degeneration and…”
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The Human Hyaloid System: Cell Death and Vascular Regression by Zhu, Meidong, Madigan, Michele C, van Driel, Diana, Maslim, Juliani, Billson, Francis A, Provis, Jan M, Penfold, Philip L

“…The present study had investigated the roles of apoptosis and necrosis in the regression of the human fetal hyaloid vasculature. Normal human fetal hyaloid…”
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Inflammation and Age-Related Macular Degeneration by Penfold, Philip L

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Development of microglial topography in human retina by Diaz-Araya, C M, Provis, J M, Penfold, P L, Billson, F A

“…The development of microglial topography in wholemounts of human retina has been examined in the age range 10-25 weeks gestation (WG) using histochemistry and…”
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Human retinal microglia: expression of immune markers and relationship to the glia limitans by Provis, J M, Penfold, P L, Edwards, A J, van Driel, D

“…The immunoreactivity, morphology and relationship to the glia limitans of microglia were investigated in flatmounts and sections of normal human retina, using…”
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Astrocyte Proliferation During Development of the Human Retinal Vasculature by SANDERCOE, TRENT M., MADIGAN, MICHELE C., BILLSON, FRANCIS A., PENFOLD, PHILIP L., PROVIS, JAN M.

“…Wholemounts of human fetal retinas were labeled with antibodies to Ki67 or proliferating cell nuclear antigen, to map the distribution of proliferating cells…”
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Effects of post-mortem delay and storage duration on the expression of GFAP in normal human adult retinae by Wu, Kathy HC, Penfold, Philip L, Billson, Francis A

“…Glial fibrillary acidic protein (GFAP) is an established marker of retinal glia and has been shown to be modulated by several cytokines and retinal pathology…”
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Immunoglobulin superfamily expression in primary retinoblastoma and retinoblastoma cell lines by Madigan, Michele C, Penfold, Philip L, King, Nicholas J C, Billson, Francis A, Conway, Robert M

“…Retinoblastoma (Rb) is the most common intraocular tumor of childhood. In this study we examined primary Rb specimens and Rb cell lines for the expression of…”
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Sodium butyrate modulates p53 and Bcl-2 expression in human retinoblastoma cell lines by Madigan, M C, Chaudhri, G, Penfold, P L, Conway, R M

“…Sodium butyrate (SB) is a potent biological modifier that can induce diverse effects including growth inhibition, differentiation, or apoptosis of many cell…”
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Modulation of MHC class II expression in the absence of lymphocytic infiltrates in Alzheimer's retinae by Liew, S C, Penfold, P L, Provis, J M, Madigan, M C, Billson, F A

“…This study describes the expression of MHC class II antigens in retinal flat mounts from normal donors and patients with Alzheimer's disease (AD). We confirm…”
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Angiogenesis in normal human retinal development: the involvement of astrocytes and macrophages by PENFOLD, P. L, PROVIS, J. M, MADIGAN, M. C, VAN DRIEL, D, BILLSON, F. A

“…Recent studies have suggested a role for mononuclear phagocytes series (MPS) cells in neovascularisation associated with retinal pathology and experimentally…”
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Exudative macular degeneration and intravitreal triamcinolone A pilot study by Penfold, Philip L., Gyory, Joseph F., Hunyor, Alex B., Billson, Francis A.

“…Purpose: To study the efficacy of the anti‐inflammatory agent triamcinolone (Kenacort A‐40) in patients with exudative age‐related macular degeneration and…”
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Ultrastructural features of contact lens-induced deep corneal neovascularization and associated stromal leukocytes by Madigan, M C, Penfold, P L, Holden, B A, Billson, F A

“…Deep stromal vascularization was observed in corneas of four cynomolgus monkeys after extended monocular hydrogel contact lens wear. Keratocytes and…”
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