Search Results - "PENACK, Olaf"

Hemophagocytic lymphohistiocytosis in adults: collaborative analysis of 137 cases of a nationwide German registry by Birndt, Sebastian, Schenk, Thomas, Heinevetter, Babett, Brunkhorst, Frank M., Maschmeyer, Georg, Rothmann, Frank, Weber, Thomas, Müller, Markus, Panse, Jens, Penack, Olaf, Schroers, Roland, Braess, Jan, Frickhofen, Norbert, Ehl, Stephan, Janka, Gritta, Lehmberg, Kai, Pletz, Mathias W., Hochhaus, Andreas, Ernst, Thomas, La Rosée, Paul

“…Purpose Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory syndrome emerging from a deregulated immune response due to various triggers. In…”
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Central venous catheter–related infections in hematology and oncology: 2020 updated guidelines on diagnosis, management, and prevention by the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO) by Böll, Boris, Schalk, Enrico, Buchheidt, Dieter, Hasenkamp, Justin, Kiehl, Michael, Kiderlen, Til Ramon, Kochanek, Matthias, Koldehoff, Michael, Kostrewa, Philippe, Claßen, Annika Y., Mellinghoff, Sibylle C., Metzner, Bernd, Penack, Olaf, Ruhnke, Markus, Vehreschild, Maria J. G. T., Weissinger, Florian, Wolf, Hans-Heinrich, Karthaus, Meinolf, Hentrich, Marcus

“…Cancer patients frequently require central venous catheters for therapy and parenteral nutrition and are at high risk of central venous catheter–related…”
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Acute Graft-versus-Host-Disease Other Than Typical Targets: Between Myths and Facts by Mariotti, Jacopo, Penack, Olaf, Castagna, Luca

“…•Skin, liver, and gut are not the only organs involved in acute graft-versus-host disease (aGVHD).•Kidney, bone marrow, central nervous system, and lung may be…”
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EASIX and mortality after allogeneic stem cell transplantation by Luft, Thomas, Benner, Axel, Terzer, Tobias, Jodele, Sonata, Dandoy, Christopher E., Storb, Rainer, Kordelas, Lambros, Beelen, Dietrich, Gooley, Ted, Sandmaier, Brenda M., Sorror, Mohamed, Zeisbrich, Markus, Radujkovic, Aleksandar, Dreger, Peter, Penack, Olaf

“…Allogeneic stem cell transplantation (alloSCT) is an effective immunotherapy in patients with hematological malignancies. Endothelial dysfunction was linked to…”
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Diagnosis and Management of Secondary HLH/MAS Following HSCT and CAR-T Cell Therapy in Adults; A Review of the Literature and a Survey of Practice Within EBMT Centres on Behalf of the Autoimmune Diseases Working Party (ADWP) and Transplant Complications Working Party (TCWP) by Sandler, Robert David, Tattersall, Rachel Scarlett, Schoemans, Helene, Greco, Raffaella, Badoglio, Manuela, Labopin, Myriam, Alexander, Tobias, Kirgizov, Kirill, Rovira, Montserrat, Saif, Muhammad, Saccardi, Riccardo, Delgado, Julio, Peric, Zinaida, Koenecke, Christian, Penack, Olaf, Basak, Grzegorz, Snowden, John Andrew

“…Secondary haemophagocytic lymphohistiocytosis (sHLH) or Macrophage Activation Syndrome (MAS) is a life-threatening hyperinflammatory syndrome that can occur in…”
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Primary CD33-targeting CAR-NK cells for the treatment of acute myeloid leukemia by Albinger, Nawid, Pfeifer, Rita, Nitsche, Marcus, Mertlitz, Sarah, Campe, Julia, Stein, Katja, Kreyenberg, Hermann, Schubert, Ralf, Quadflieg, Melissa, Schneider, Dina, Kühn, Michael W. M., Penack, Olaf, Zhang, Congcong, Möker, Nina, Ullrich, Evelyn

“…Acute myeloid leukemia (AML) is a malignant disorder derived from neoplastic myeloid progenitor cells characterized by abnormal proliferation and…”
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Editorial: Emerging talents in alloimmunity and transplantation: 2022 by Moll, Guido, Lim, Wai H, Penack, Olaf

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Infectious diseases in allogeneic haematopoietic stem cell transplantation: prevention and prophylaxis strategy guidelines 2016 by Ullmann, Andrew J., Schmidt-Hieber, Martin, Bertz, Hartmut, Heinz, Werner J., Kiehl, Michael, Krüger, William, Mousset, Sabine, Neuburger, Stefan, Neumann, Silke, Penack, Olaf, Silling, Gerda, Vehreschild, Jörg Janne, Einsele, Hermann, Maschmeyer, Georg

“…Infectious complications after allogeneic haematopoietic stem cell transplantation (allo-HCT) remain a clinical challenge. This is a guideline provided by the…”
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Predicting sinusoidal obstruction syndrome after allogeneic stem cell transplantation with the EASIX biomarker panel by Jiang, Sihe, Penack, Olaf, Terzer, Tobias, Schult, David, Majer-Lauterbach, Joshua, Radujkovic, Aleksandar, Blau, Igor W, Bullinger, Lars, Müller-Tidow, Carsten, Dreger, Peter, Luft, Thomas

“…No biomarker panel is established for prediction of sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD), a major complication of allogeneic stem…”
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Management of complications of chimeric antigen receptor T-cell therapy: a report by the European Society of Blood and Marrow Transplantation by Penack, Olaf, Peczynski, Christophe, Boreland, William, Wolff, Daniel, Moiseev, Ivan, Schoemans, Hélène, Koenecke, Christian, Graham, Charlotte, Peric, Zinaida

“…CAR-T cells are in standard clinical use to treat relapsed or refractory hematologic malignancies, such as non-Hodgkin's lymphoma, multiple myeloma and acute…”
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How much has allogeneic stem cell transplant–related mortality improved since the 1980s? A retrospective analysis from the EBMT by Penack, Olaf, Peczynski, Christophe, Mohty, Mohamad, Yakoub-Agha, Ibrahim, Styczynski, Jan, Montoto, Silvia, Duarte, Rafael F., Kröger, Nicolaus, Schoemans, Hélène, Koenecke, Christian, Peric, Zinaida, Basak, Grzegorz W.

“…We performed a study to find out how advances in modern medicine have improved the mortality risk of allogeneic stem cell transplantation. We analyzed major…”
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Editorial: Endothelial Dysfunction During Inflammation and Alloimmunity by Penack, Olaf, Luft, Thomas

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Primary prophylaxis of bacterial infections and Pneumocystis jirovecii pneumonia in patients with hematologic malignancies and solid tumors: 2020 updated guidelines of the Infectious Diseases Working Party of the German Society of Hematology and Medical Oncology (AGIHO/DGHO) by Classen, Annika Y., Henze, Larissa, von Lilienfeld-Toal, Marie, Maschmeyer, Georg, Sandherr, Michael, Graeff, Luisa Durán, Alakel, Nael, Christopeit, Maximilian, Krause, Stefan W., Mayer, Karin, Neumann, Silke, Cornely, Oliver A., Penack, Olaf, Weißinger, Florian, Wolf, Hans-Heinrich, Vehreschild, Jörg Janne

“…Hematologic and oncologic patients with chemo- or immunotherapy-related immunosuppression are at substantial risk for bacterial infections and Pneumocystis…”
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Association of pre-existing comorbidities with outcome of allogeneic hematopoietic cell transplantation. A retrospective analysis from the EBMT by Penack, Olaf, Peczynski, Christophe, Mohty, Mohamad, Yakoub-Agha, Ibrahim, de la Camara, Rafael, Glass, Bertram, Duarte, Rafael F., Kröger, Nicolaus, Schoemans, Hélène, Koenecke, Christian, Peric, Zinaida, Basak, Grzegorz W.

“…Risk assessment of allogeneic hematopoietic cell transplantation (allo-HCT) is hindered by the lack of current data on comorbidities and outcome. The EBMT…”
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The CAR-HEMATOTOX risk-stratifies patients for severe infections and disease progression after CD19 CAR-T in R/R LBCL by Rejeski, Kai, Perez, Ariel, Iacoboni, Gloria, Penack, Olaf, Bücklein, Veit, Jentzsch, Liv, Mougiakakos, Dimitrios, Johnson, Grace, Arciola, Brian, Carpio, Cecilia, Blumenberg, Viktoria, Hoster, Eva, Bullinger, Lars, Locke, Frederick L, von Bergwelt-Baildon, Michael, Mackensen, Andreas, Bethge, Wolfgang, Barba, Pere, Jain, Michael D, Subklewe, Marion

“…BackgroundCD19-directed chimeric antigen receptor T-cell therapy (CAR-T) represents a promising treatment modality for an increasing number of B-cell…”
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Prophylaxis, diagnosis and therapy of infections in patients undergoing high-dose chemotherapy and autologous haematopoietic stem cell transplantation. 2020 update of the recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO) by Christopeit, Maximilian, Schmidt-Hieber, Martin, Sprute, Rosanne, Buchheidt, Dieter, Hentrich, Marcus, Karthaus, Meinolf, Penack, Olaf, Ruhnke, Markus, Weissinger, Florian, Cornely, Oliver A., Maschmeyer, Georg

“…To ensure the safety of high-dose chemotherapy and autologous stem cell transplantation (HDC/ASCT), evidence-based recommendations on infectious complications…”
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The induction strategies administered in the treatment of multiple myeloma exhibit a deleterious effect on the endothelium by Martinez-Sanchez, Julia, Palomo, Marta, Torramade-Moix, Sergi, Moreno-Castaño, Ana Belen, Rovira, Montserrat, Gutiérrez-García, Gonzalo, Fernández-Avilés, Francesc, Escolar, Gines, Penack, Olaf, Rosiñol, Laura, Carreras, Enric, Diaz-Ricart, Maribel

“…Multiple myeloma induction treatment includes proteasome inhibitors (PI) and immunomodulatory agents at present. The incidence of engraftment syndrome, a…”
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Improved outcome of patients with graft-versus-host disease after allogeneic hematopoietic cell transplantation for hematologic malignancies over time: an EBMT mega-file study by Greinix, Hildegard T, Eikema, Dirk-Jan, Koster, Linda, Penack, Olaf, Yakoub-Agha, Ibrahim, Montoto, Silvia, Chabannon, Christian, Styczynski, Jan, Nagler, Arnon, Robin, Marie, Robinson, Stephen, Chalandon, Yves, Mikulska, Malgorzata, Schönland, Stefan, Peric, Zinaida, Ruggeri, Annalisa, Lanza, Francesco, De Wreede, Liesbeth C, Mohty, Mohamad, Basak, Grzegorz W, Kröger, Nicolaus

“…Acute graft-versus-host disease (aGvHD) remains a major threat to successful outcome following allogeneic hematopoietic cell transplantation though advances in…”
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EASIX and Severe Endothelial Complications After CD19-Directed CAR-T Cell Therapy-A Cohort Study by Korell, Felix, Penack, Olaf, Mattie, Mike, Schreck, Nicholas, Benner, Axel, Krzykalla, Julia, Wang, Zixing, Schmitt, Michael, Bullinger, Lars, Müller-Tidow, Carsten, Dreger, Peter, Luft, Thomas

“…Endothelial dysfunction is associated with two main complications of chimeric antigen receptor T (CAR-T) cell therapy, cytokine release syndrome (CRS) and…”
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Graft-versus-host disease: regulation by microbe-associated molecules and innate immune receptors by Penack, Olaf, Holler, Ernst, van den Brink, Marcel R.M.

“…Acute graft-versus-host disease (GVHD) remains the major obstacle to a more favorable therapeutic outcome of allogeneic hematopoietic stem cell transplantation…”
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