Search Results - "PELLEGATA, Alessandro F"
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Whole Organ Tissue Vascularization: Engineering the Tree to Develop the Fruits
Published in Frontiers in bioengineering and biotechnology (14-05-2018)“…Tissue engineering aims to regenerate and recapitulate a tissue or organ that has lost its function. So far successful clinical translation has been limited to…”
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Arterial Decellularized Scaffolds Produced Using an Innovative Automatic System
Published in Cells, tissues, organs (01-12-2015)“…There is still an unmet clinical need for small-caliber artery substitution. Decellularized scaffolds in tissue engineering represent a promising solution. We…”
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A Perfusion Bioreactor for Longitudinal Monitoring of Bioengineered Liver Constructs
Published in Nanomaterials (Basel, Switzerland) (21-01-2021)“…In the field of in vitro liver disease models, decellularised organ scaffolds maintain the original biomechanical and biological properties of the…”
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Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis
Published in Nature (London) (17-09-2020)“…Endothelial cells adopt tissue-specific characteristics to instruct organ development and regeneration 1 , 2 . This adaptability is lost in cultured adult…”
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Conjugated polymers mediate intracellular Ca2+ signals in circulating endothelial colony forming cells through the reactive oxygen species-dependent activation of Transient Receptor Potential Vanilloid 1 (TRPV1)
Published in Cell calcium (Edinburgh) (01-01-2022)“…•Optical excitation of rr-P3HT thin films induces a long-lasting increase in [Ca2+]i in circulating endothelial colony forming cells (ECFCs).•The Ca2+ response…”
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Whole rat stomach decellularisation using a detergent-enzymatic protocol
Published in Pediatric surgery international (01-01-2019)“…Background Conditions leading to reduced gastric volume are difficult to manage and are associated to poor quality-of-life. Stomach augmentation using a…”
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Detergent-Enzymatic Decellularization of Swine Blood Vessels: Insight on Mechanical Properties for Vascular Tissue Engineering
Published in BioMed research international (01-01-2013)“…Small caliber vessels substitutes still remain an unmet clinical need; few autologous substitutes are available, while synthetic grafts show insufficient…”
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Alternating air-medium exposure in rotating bioreactors optimizes cell metabolism in 3D novel tubular scaffold polyurethane foams
Published in Journal of applied biomaterials & functional materials (01-04-2017)“…In vitro dynamic culture conditions play a pivotal role in developing engineered tissue grafts, where the supply of oxygen and nutrients, and waste removal…”
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A novel device for the automatic decellularization of biological tissues
Published in International journal of artificial organs (01-03-2012)“…Decellularized biological scaffolds represent a promising solution for tissue engineering. They offer a good substrate for cells in terms of biochemical…”
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Terminal sterilization of equine-derived decellularized tendons for clinical use
Published in Materials Science & Engineering C (01-06-2017)“…In the last few years, the demand for tissue substitutes has increased and decellularized matrices has been widely proposed in the medical field to restore…”
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A bioengineered approach to re-create and study the extracellular matrix-immune cell crosstalk in normal and fibrotic liver
Published in Journal of hepatology (01-07-2022)Get full text
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Conjugated polymers mediate intracellular Ca 2+ signals in circulating endothelial colony forming cells through the reactive oxygen species-dependent activation of Transient Receptor Potential Vanilloid 1 (TRPV1)
Published in Cell calcium (Edinburgh) (01-01-2022)“…Endothelial colony forming cells (ECFCs) represent the most suitable cellular substrate to induce revascularization of ischemic tissues. Recently, optical…”
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