Search Results - "PEKARSKY, Y."

Role of miR-15/16 in CLL by Pekarsky, Y, Croce, C M

“…B-cell chronic lymphocytic leukemia (CLL) is the most common adult leukemia. The most common chromosomal abnormalities detectable by cytogenetics include…”
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Correction to: Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential by Semba, S., Trapasso, F., Fabbri, M., McCorkell, K. A., Volinia, S., Druck, T., Iliopoulos, D., Pekarsky, Y., Ishii, H., Garrison, P. N., Barnes, L. D., Croce, C. M., Huebner, K.

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Correction: Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential by Semba, S., Trapasso, F., Fabbri, M., McCorkell, K. A., Volinia, S., Druck, T., Iliopoulos, D., Pekarsky, Y., Ishii, H., Garrison, P. N., Barnes, L. D., Croce, C. M., Huebner, K.

“…After publication of this Article the authors noticed errors in several figures. In Fig. 2b the Gapdh panels are incorrect. The lysates are identical to those…”
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CD5+CD23+ leukemic cell populations in TCL1 transgenic mice show significantly increased proliferation and Akt phosphorylation by Efanov, A, Zanesi, N, Nazaryan, N, Santanam, U, Palamarchuk, A, Croce, C M, Pekarsky, Y

“…B-cell chronic lymphocytic leukemia (B-CLL) is the most common adult leukemia. Deregulation of the T-cell leukemia/lymphoma 1 ( TCL1 ) oncogene in mouse B…”
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Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential by SEMBA, S, TRAPASSO, F, BARNES, L. D, CROCE, C. M, HUEBNER, K, FABBRI, M, MCCORKELL, K. A, VOLINIA, S, DRUCK, T, ILIOPOULOS, D, PEKARSKY, Y, ISHII, H, GARRISON, P. N

“…The Fhit tumor suppressor binds and hydrolyses diadenosine polyphosphates and the Fhit-substrate complex has been proposed as a proapoptotic effector, as…”
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Trisomy 12 CLLs progress through NOTCH1 mutations by Balatti, V, Lerner, S, Rizzotto, L, Rassenti, L Z, Bottoni, A, Palamarchuk, A, Cascione, L, Alder, H, Keating, M J, Kipps, T J, Pekarsky, Y, Croce, C M

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Crystal structure of the worm NitFhit Rosetta Stone protein reveals a Nit tetramer binding two Fhit dimers by Pace, H.C, Hodawadekar, S.C, Draganescu, A, Huang, J, Bieganowski, P, Pekarsky, Y, Croce, C.M, Brenner, C

“…Background: The nucleotide-binding protein Fhit, among the earliest and most frequently inactivated proteins in lung cancer, suppresses tumor formation by…”
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Chronic lymphocytic leukemia: molecular genetics and animal models by Pekarsky, Y, Calin, G A, Aqeilan, R

“…Chronic lymphocytic leukemia accounts for almost 30% of all adult leukemia cases in the United States and Western Europe. Although several common genomic…”
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Pre-B Cell Proliferation and Lymphoblastic Leukemia/High-Grade Lymphoma in Eμ-miR155 Transgenic Mice by Costinean, Stefan, Zanesi, Nicola, Pekarsky, Yuri, Tili, Esmerina, Volinia, Stefano, Heerema, Nyla, Croce, Carlo M.

“…MicroRNAs (miRNAs) represent a newly discovered class of posttranscriptional regulatory noncoding small RNAs that bind to targeted mRNAs and either block their…”
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A second-generation YAC contig map of human chromosome 3 by Gemmill, R M, Chumakov, I, Scott, P, Waggoner, B, Rigault, P, Cypser, J, Chen, Q, Weissenbach, J, Gardiner, K, Wang, H

“…A map of human chromosome 3 which integrates both physical and genetic data has been developed from the fusion of two large collections of markers and…”
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The Human Myosin Light Chain Kinase (MLCK) from Hippocampus: Cloning, Sequencing, Expression, and Localization to 3qcen–q21 by POTIER, M.-C., CHELOT, E., PEKARSKY, Y., GARDINER, K., ROSSIER, J., TURNELL, W.G.

“…Myosin light chain kinase (MLCK), a key enzyme in muscle contraction, has been shown by immunohistology to be present in neurons and glia. We describe here the…”
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Fhit protein expression in oral epithelium: immunohistochemical evaluation of three antisera by van Heerden, W F, Swart, T J, van Heerden, M B, Pekarsky, Y, Sutherland, R, Huebner, K

“…A number of studies have shown that the Fhit tumour suppressor protein is abundantly expressed in normal epithelial cells of human organs and that this…”
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Ww domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function by AQEILAN, Rami I, DONATI, Valentina, PALAMARCHUK, Alexey, TRAPASSO, Francesco, KAOU, Mohamed, PEKARSKY, Yuri, SUDOL, Marius, CROCE, Carlo M

“…The WW domain-containing oxidoreductase, WWOX, is a tumor suppressor that is deleted or altered in several cancer types. We recently showed that WWOX interacts…”
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Activation of a novel gene in 3q21 and identification of intergenic fusion transcripts with ecotropic viral insertion site I in leukemia by PEKARSKY, YU, RYNDITCH, A, WIESER, R, FONATSCH, C, GARDINER, K

“…We have identified a novel gene, GR6, located within the leukemia breakpoint region of 3q21, that is normally expressed in early fetal development but not in…”
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Akt phosphorylates and regulates Pdcd4 tumor suppressor protein by PALAMARCHUK, Alexey, EFANOV, Alexey, MAXIMOV, Vadim, AQEILAN, Rami I, CROCE, Carlo M, PEKARSKY, Yuri

“…Programmed cell death 4 (Pdcd4) is a tumor suppressor protein that interacts with eukaryotic initiation factor 4A and inhibits protein synthesis. Pdcd4 also…”
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Functional Association between Wwox Tumor Suppressor Protein and p73, a p53 Homolog by Aqeilan, Rami I., Pekarsky, Yuri, Herrero, Juan J., Palamarchuk, Alexey, Letofsky, Jean, Druck, Teresa, Trapasso, Francesco, Han, Shuang-Yin, Melino, Gerry, Huebner, Kay, Croce, Carlo M.

“…The WWOX gene is a recently cloned tumor suppressor gene that spans the FRA16D fragile region. Wwox protein contains two WW domains that are generally known to…”
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Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2γ transcription factor by AQEILAN, Rami I, PALAMARCHUK, Alexey, WEIGEL, Ronald J, HERRERO, Juan J, PEKARSKY, Yuri, CROCE, Carlo M

“…The WWOX gene encodes a tumor suppressor WW domain-containing protein, Wwox. Alterations of WWOX have been demonstrated in multiple types of cancer, and…”
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FHIT: from gene discovery to cancer treatment and prevention by Pekarsky, Yuri, Zanesi, Nicola, Palamarchuk, Alexey, Huebner, Kay, Croce, Carlo M

“…Chromosomal abnormalities, including homozygous deletions and loss of heterozygosity, are among the most common features of human tumours. The short arm of…”
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Tcl1 Enhances Akt Kinase Activity and Mediates Its Nuclear Translocation by Pekarsky, Yuri, Koval, Anatoliy, Hallas, Cora, Bichi, Roberta, Tresini, Maria, Malstrom, Scott, Russo, Giandomenico, Tsichlis, Philip, Croce, Carlo M.

“…The TCL1 oncogene at 14q32.1 is involved in the development of human mature T-cell leukemia. The mechanism of action of Tcl1 is unknown. Because the virus…”
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Loss of WWOX Expression in Gastric Carcinoma by AQEILAN, Rami I, KUROKI, Tamotsu, PEKARSKY, Yuri, ALBAGHA, Omar, TRAPASSO, Francesco, BAFFA, Raffaele, HUEBNER, Kay, EDMONDS, Pamela, CROCE, Carlo M

“…Purpose: WW domain-containing oxidoreductase ( WWOX ) is a tumor suppressor gene that maps to the common fragile site FRA16D on chromosome 16q23.3–24.1. To…”
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