Search Results - "PEJNOVIC, Nada"
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Interleukin‐33/ST2 axis promotes breast cancer growth and metastases by facilitating intratumoral accumulation of immunosuppressive and innate lymphoid cells
Published in International journal of cancer (01-04-2014)“…The role of IL‐33/ST2 pathway in antitumor immunity is unclear. Using 4T1 breast cancer model we demonstrate time‐dependent increase of endogenous IL‐33 at…”
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2
Differential Immunometabolic Phenotype in Th1 and Th2 Dominant Mouse Strains in Response to High-Fat Feeding
Published in PloS one (28-07-2015)“…Immune reactivity plays an important role in obesity-associated metabolic disorders. We investigated immunometabolic phenotype of C57Bl/6 and BALB/c mice,…”
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IL-33/ST2 axis in inflammation and immunopathology
Published in Immunologic research (01-04-2012)“…Interleukin-33 (IL-33), a member of the IL-1 family of cytokines, binds to its plasma membrane receptor, heterodimeric complex consisted of membrane-bound ST2L…”
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4
Galectin-3 Deficiency Accelerates High-Fat Diet―Induced Obesity and Amplifies Inflammation in Adipose Tissue and Pancreatic Islets
Published in Diabetes (New York, N.Y.) (01-06-2013)“…Obesity-induced diabetes is associated with low-grade inflammation in adipose tissue and macrophage infiltration of islets. We show that ablation of galectin-3…”
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5
Galectin-3 and IL-33/ST2 axis roles and interplay in diet-induced steatohepatitis
Published in World journal of gastroenterology : WJG (28-11-2016)“…Immune reactivity and chronic low-grade inflammation (metaflammation) play an important role in the pathogenesis of obesity-associated metabolic disorders,…”
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Phenethyl ester of rosmarinic acid attenuates autoimmune responses during type 1 diabetes development in mice
Published in Life sciences (1973) (01-01-2022)“…Rosmarinic acid (RA) is a polyphenol that occurs in plants of the Lamiaceae family. Phenethyl ester of RA (PERA), a novel RA derivative, has been developed and…”
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7
Galectin-3 Ablation Enhances Liver Steatosis, but Attenuates Inflammation and IL-33-Dependent Fibrosis in Obesogenic Mouse Model of Nonalcoholic Steatohepatitis
Published in Molecular medicine (Cambridge, Mass.) (01-01-2015)“…The importance of Galectin-3 (Gal-3) in obesity-associated liver pathology is incompletely defined. To dissect the role of Gal-3 in fibrotic nonalcoholic…”
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The roles of Galectin-3 in autoimmunity and tumor progression
Published in Immunologic research (01-04-2012)“…Galectin-3, a unique chimera-type member of the β-galactoside-binding soluble lectin family, is widely expressed in numerous cells. Here, we discuss the role…”
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9
Immunomodulatory activity and protective effects of chokeberry fruit extract on Listeria monocytogenes infection in mice
Published in Food & function (23-09-2020)“…Chokeberry (Aronia melanocarpa) fruit extracts (CE) are rich in polyphenols and usually exhibit immunomodulatory, anti-viral and anti-bacterial effects. We…”
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Overexpression of Galectin 3 in Pancreatic β Cells Amplifies β-Cell Apoptosis and Islet Inflammation in Type-2 Diabetes in Mice
Published in Frontiers in endocrinology (Lausanne) (07-02-2020)“…Galectin 3 appears to play a proinflammatory role in several inflammatory and autoimmune diseases. Also, there is evidence that galectin 3 plays a role in both…”
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Transgenic Overexpression of Galectin-3 in Pancreatic β Cells Attenuates Hyperglycemia in Mice: Synergistic Antidiabetic Effect With Exogenous IL-33
Published in Frontiers in pharmacology (05-11-2021)“…Galectin-3 (Gal-3) has diverse roles in inflammatory and autoimmune diseases. There is evidence that Gal-3 plays a role in both type 1 and type 2 diabetes…”
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Diagnostic Value of Salivary Gland Ultrasonographic Scoring System in Primary Sjögren's Syndrome: A Comparison with Scintigraphy and Biopsy
Published in Journal of rheumatology (01-07-2009)“…To compare an ultrasonographic (US) scoring system of salivary glands with scintigraphy and salivary gland biopsy, in order to evaluate its diagnostic value in…”
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13
Deletion of IL-33R attenuates VEGF expression and enhances necrosis in mammary carcinoma
Published in Oncotarget (05-04-2016)“…Interleukin-33 (IL-33)/IL-33 receptor (IL-33R, ST2) signaling pathway promotes mammary cancer growth and metastasis by inhibiting anti-tumor immunity. However,…”
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IL-33/ST2 axis in innate and acquired immunity to tumors
Published in Oncoimmunology (01-03-2012)“…Interleukin-33, a ligand for ST2/T1, has an important role in allergy, autoimmunity and inflammation. The role of IL-33/ST2 axis in cancer is not elucidated…”
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Tumor Necrosis Factor Blockade Differentially Affects Innate Inflammatory and Th17 Cytokines in Rheumatoid Arthritis
Published in Journal of rheumatology (01-01-2012)“…To evaluate the effect of a tumor necrosis factor-α (TNF-α) inhibitor (etanercept) on innate inflammatory and Th17 cytokines in patients with rheumatoid…”
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ST2 Deletion Increases Inflammatory Bone Destruction in Experimentally Induced Periapical Lesions in Mice
Published in Journal of endodontics (01-03-2015)“…Abstract Introduction ST2 is a member of the interleukin (IL)-1 receptor family, and IL-33 is its natural ligand. ST2 signaling promotes Th2 immune response in…”
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Galectin-3 deficiency prevents concanavalin A-induced hepatitis in mice
Published in Hepatology (Baltimore, Md.) (01-06-2012)Get full text
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Clinical significance of Cyclin D1, FGF3 and p21 protein expression in laryngeal squamous cell carcinoma
Published in Journal of B.U. ON. (01-10-2014)“…Laryngeal squamous cell carcinoma (LSCC) represents one of the most common cancers of the head and neck and the search for molecular markers is required for…”
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Modulation of Intestinal ILC3 for the Treatment of Type 1 Diabetes
Published in Frontiers in immunology (03-06-2021)“…Gut-associated lymphoid tissue (GALT) is crucial for the maintenance of the intestinal homeostasis, but it is also the potential site of the activation of…”
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Galectin-3 is a regulator of metaflammation in adipose tissue and pancreatic islets
Published in Adipocyte (22-10-2013)“…The cells of the innate and adaptive immune systems have been implicated in the development of obesity-induced metaflammation and metabolic disorders including…”
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