Search Results - "PEDRAZZINI, T"

Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long non-coding RNAs by Ounzain, Samir, Micheletti, Rudi, Beckmann, Tal, Schroen, Blanche, Alexanian, Michael, Pezzuto, Iole, Crippa, Stefania, Nemir, Mohamed, Sarre, Alexandre, Johnson, Rory, Dauvillier, Jérôme, Burdet, Frédéric, Ibberson, Mark, Guigó, Roderic, Xenarios, Ioannis, Heymans, Stephane, Pedrazzini, Thierry

“…Heart disease is recognized as a consequence of dysregulation of cardiac gene regulatory networks. Previously, unappreciated components of such networks are…”
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Neuropeptide Y: the universal soldier by Pedrazzini, T, Pralong, F, Grouzmann, E

“…The peptidic neuropeptide Y (NPY) has received great attention because it has been implicated in the regulation of several organ systems. In particular, NPY is…”
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Dissecting the transcriptome in cardiovascular disease by Robinson, Emma L, Baker, Andrew H, Brittan, Mairi, McCracken, Ian, Condorelli, G, Emanueli, C, Srivastava, P K, Gaetano, C, Thum, T, Vanhaverbeke, M, Angione, C, Heymans, S, Devaux, Y, Pedrazzini, T, Martelli, F

“…Abstract The human transcriptome comprises a complex network of coding and non-coding RNAs implicated in a myriad of biological functions. Non-coding RNAs…”
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gp91phox-containing NADPH oxidase mediates Endothelial dysfunction in renovascular hypertension by JUNG, O, SCHREIBER, J. G, GEIGER, H, PEDRAZZINI, T, BUSSE, R, BRANDES, R. P

“…Isoforms of the NADPH oxidase contribute to vascular superoxide anion (*O2-) formation and limit NO bioavailability. We hypothesized that the endothelial…”
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Ischemic postconditioning protects remodeled myocardium via the PI3K-PKB/Akt reperfusion injury salvage kinase pathway by MIN ZHU, JIANHUA FENG, LUCCHINETTI, Eliana, FISCHER, Gregor, LIN XU, PEDRAZZINI, Thierry, SCHAUB, Marcus C, ZAUGG, Michael

“…We tested whether ischemic postconditioning (IPostC) is protective in remodeled myocardium. Post-myocardial infarct (MI)-remodeled hearts after permanent…”
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Expression of the neuropeptide Y Y1 receptor in the CNS of rat and of wild-type and Y1 receptor knock-out mice. Focus on immunohistochemical localization by Kopp, J, Xu, Z.-Q, Zhang, X, Pedrazzini, T, Herzog, H, Kresse, A, Wong, H, Walsh, J.H, Hökfelt, T

“…The distribution of neuropeptide Y (NPY) Y1 receptor-like immunoreactivity (Y1R-LI) has been studied in detail in the CNS of rat using a rabbit polyclonal…”
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Y1 receptor knockout increases nociception and prevents the anti-allodynic actions of NPY by Kuphal, K.E., Ph.D, Solway, B., Ph.D, Pedrazzini, T., Ph.D, Taylor, B.K., Ph.D

“…Abstract Objective Recent pharmacologic studies in our laboratory have suggested that the spinal neuropeptide Y (NPY) Y1 receptor contributes to pain…”
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Fate of human crardiac precursoe cells following injection in the sheep myocardium using a NOGA cell delivery system by Fluri, S. M. Perruchoud, Pedrazzini, T, Ruchat, P, Pruvot, E, Gonzales, C, Plaisance, I, Locca, D

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Deletion of the neuropeptide YY1 receptor affects pain sensitivity, neuropeptide transport and expression, and dorsal root ganglion neuron numbers by Shi, TJS, Li, J, Dahlström, A, Theodorsson, E, Ceccatelli, S, Decosterd, I, Pedrazzini, T, Hökfelt, T

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Chronic administration of neuropeptide Y into the lateral ventricle of C57BL/6J male mice produces an obesity syndrome including hyperphagia, hyperleptinemia, insulin resistance, and hypogonadism by Raposinho, P.D., Pierroz, D.D., Broqua, P., White, R.B., Pedrazzini, T., Aubert, M.L.

“…Neuropeptide Y (NPY) is involved in the central regulation of appetite, sexual behavior, and reproductive function. We have previously shown that chronic…”
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Deletion of the neuropeptide Y Y1 receptor affects pain sensitivity, neuropeptide transport and expression, and dorsal root ganglion neuron numbers by Shi, T.-J.S., Li, J., Dahlström, A., Theodorsson, E., Ceccatelli, S., Decosterd, I., Pedrazzini, T., Hökfelt, T.

“…Neuropeptide Y has been implicated in pain modulation and is substantially up-regulated in dorsal root ganglia after peripheral nerve injury. To identify the…”
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Selective Expression of a Dominant-Negative Form of Peroxisome Proliferator-Activated Receptor in Keratinocytes Leads to Impaired Epidermal Healing by Michalik, L, Feige, J. N, Gelman, L, Pedrazzini, T, Keller, H, Desvergne, B, Wahli, W

“…Many nuclear hormone receptors are involved in the regulation of skin homeostasis. However, their role in the epithelial compartment of the skin in stress…”
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Calcineurin Blockade Prevents Cardiac Mitogen-activated Protein Kinase Activation and Hypertrophy in Renovascular Hypertension by Murat, Anastasia, Pellieux, Corinne, Brunner, Hans-R., Pedrazzini, Thierry

“…Chronic stimulation of the renin-angiotensin system induces an elevation of blood pressure and the development of cardiac hypertrophy via the actions of its…”
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N004 Isolation of cardiac precursor cells from the human fetal heart by Gonzales, C, Gerber, S, Berthonneche, C, Pedrazzini, T

“…To identify a suitable source of human cardiac precursor cells (CPC) for replacement cell therapies, we established the conditions to isolate precursors from…”
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Identification of corticosteroid-regulated genes in cardiomyocytes by serial analysis of gene expression by Muller, Olivier, Pradervand, Sylvain, Berger, Stefan, Centeno, Gabriel, Milet, Aude, Nicod, Pascal, Pedrazzini, Thierry, Tronche, François, Schütz, Günter, Chien, Kenneth, Rossier, Bernard C., Firsov, Dmitri

“…Corticosteroids (aldosterone, cortisol/corticosterone) exert direct functional effects on cardiomyocytes. However, gene networks activated by corticosteroids…”
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S100A1 deficiency results in prolonged ventricular repolarization in response to sympathetic activation by Ackermann, G E, Domenighetti, A A, Deten, A, Bonath, I, Marenholz, I, Pedrazzini, T, Erne, P, Heizmann, C W

“…S100A1 is a Ca(2+)-binding protein and predominantly expressed in the heart. We have generated a mouse line of S100A1 deficiency by gene trap mutagenesis to…”
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J007 Cardiac remodeling following chronic activation of the Notch signaling pathway by Nemir, M, Lepore, M, Cruchet, S, Felley, A, Berthonneche, C, Pedrazzini, T

“…The Notch signaling pathway is a communication system between adjacent cells, mediated by transmembrane receptors (Notch1-4) and ligands (Jagged1 and 2,…”
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N001 Generation of a transgenic model of inducible cardiomyocyte death by immuno-mediated cell targeting by Lepore, M, Nemir, M, Berthonneche, C, Kobayashi, K, Pastan, I, Pedrazzini, T

“…In the western world, heart failure, which develops for instance secondary to myocardial infarction, is a major cause of death. Usually, the heart adapts to a…”
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Neuropeptide Y Y1 receptor-deficient mice. Generation and characterization by Pedrazzini, T, Seydoux, J

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Exploring the interactions between cardiomyocytes and endothelial cells to induce cardiac revascularization and regeneration by Vuerich, R, Colliva, A, Vodret, S, Volpe, M C, Braga, L, Canarutto, G, Piazza, S, Pedrazzini, T, Chiesa, M, Cauteruccio, M, Ramadan, M, Zentilin, L, Giacca, M, Zacchigna, S

“…Abstract Funding Acknowledgements None. Background The adult heart is unable to regenerate after ischemic injury, primarily due to the incapacity of…”
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