Search Results - "PEDIATRIC NEPHROLOGY"

Oxidative stress in chronic kidney disease by Daenen, Kristien, Andries, Asmin, Mekahli, Djalila, Van Schepdael, Ann, Jouret, François, Bammens, Bert

“…Oxidative stress (OS), defined as disturbances in the pro-/antioxidant balance, is harmful to cells due to the excessive generation of highly reactive oxygen…”
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IPNA clinical practice recommendations for the diagnosis and management of children with steroid-resistant nephrotic syndrome by Trautmann, Agnes, Vivarelli, Marina, Samuel, Susan, Gipson, Debbie, Sinha, Aditi, Schaefer, Franz, Hui, Ng Kar, Boyer, Olivia, Saleem, Moin A, Feltran, Luciana, Müller-Deile, Janina, Becker, Jan Ulrich, Cano, Francisco, Xu, Hong, Lim, Yam Ngo, Smoyer, William, Anochie, Ifeoma, Nakanishi, Koichi, Hodson, Elisabeth, Haffner, Dieter

“…Idiopathic nephrotic syndrome newly affects 1–3 per 100,000 children per year. Approximately 85% of cases show complete remission of proteinuria following…”
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Exosomes and microvesicles in normal physiology, pathophysiology, and renal diseases by Ståhl, Anne-lie, Johansson, Karl, Mossberg, Maria, Kahn, Robin, Karpman, Diana

“…Extracellular vesicles are cell-derived membrane particles ranging from 30 to 5,000 nm in size, including exosomes, microvesicles, and apoptotic bodies. They…”
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An international consensus approach to the management of atypical hemolytic uremic syndrome in children by Loirat, Chantal, Fakhouri, Fadi, Ariceta, Gema, Besbas, Nesrin, Bitzan, Martin, Bjerre, Anna, Coppo, Rosanna, Emma, Francesco, Johnson, Sally, Karpman, Diana, Landau, Daniel, Langman, Craig B, Lapeyraque, Anne-Laure, Licht, Christoph, Nester, Carla, Pecoraro, Carmine, Riedl, Magdalena, van de Kar, Nicole C. A. J., Van de Walle, Johan, Vivarelli, Marina, Frémeaux-Bacchi, Véronique

“…Atypical hemolytic uremic syndrome (aHUS) emerged during the last decade as a disease largely of complement dysregulation. This advance facilitated the…”
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IPNA clinical practice recommendations for the diagnosis and management of children with steroid-sensitive nephrotic syndrome by Trautmann, Agnes, Boyer, Olivia, Hodson, Elisabeth, Bagga, Arvind, Gipson, Debbie S., Samuel, Susan, Wetzels, Jack, Alhasan, Khalid, Banerjee, Sushmita, Bhimma, Rajendra, Bonilla-Felix, Melvin, Cano, Francisco, Christian, Martin, Hahn, Deirdre, Kang, Hee Gyung, Nakanishi, Koichi, Safouh, Hesham, Trachtman, Howard, Xu, Hong, Cook, Wendy, Vivarelli, Marina, Haffner, Dieter

“…Idiopathic nephrotic syndrome is the most frequent pediatric glomerular disease, affecting from 1.15 to 16.9 per 100,000 children per year globally. It is…”
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Obesity, metabolic syndrome, and primary hypertension by Litwin, Mieczysław, Kułaga, Zbigniew

“…Primary hypertension is the dominant form of arterial hypertension in adolescents. Disturbed body composition with, among other things, increased visceral fat…”
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Expert consensus guidelines for the genetic diagnosis of Alport syndrome by Savige, Judy, Ariani, Francesca, Mari, Francesca, Bruttini, Mirella, Renieri, Alessandra, Gross, Oliver, Deltas, Constantinos, Flinter, Frances, Ding, Jie, Gale, Daniel P., Nagel, Mato, Yau, Michael, Shagam, Lev, Torra, Roser, Ars, Elisabet, Hoefele, Julia, Garosi, Guido, Storey, Helen

“…Recent expert guidelines recommend genetic testing for the diagnosis of Alport syndrome. Here, we describe current best practice and likely future…”
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Epidemiology of pediatric chronic kidney disease/kidney failure: learning from registries and cohort studies by Harada, Ryoko, Hamasaki, Yuko, Okuda, Yusuke, Hamada, Riku, Ishikura, Kenji

“…Although the concept of chronic kidney disease (CKD) in children is similar to that in adults, pediatric CKD has some peculiarities, and there is less evidence…”
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Epidemiology of chronic kidney disease in children by Harambat, Jérôme, van Stralen, Karlijn J., Kim, Jon Jin, Tizard, E. Jane

“…In the past 30 years there have been major improvements in the care of children with chronic kidney disease (CKD). However, most of the available…”
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Clinical practice recommendations for the diagnosis and management of Alport syndrome in children, adolescents, and young adults–an update for 2020 by Kashtan, Clifford E., Gross, Oliver

“…In 2013, we published a set of clinical practice recommendations for the treatment of Alport syndrome in this journal. We recommended delaying the initiation…”
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The gut–kidney axis by Evenepoel, Pieter, Poesen, Ruben, Meijers, Björn

“…The host–gut microbiota interaction has been the focus of increasing interest in recent years. It has been determined that this complex interaction is not only…”
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Genetic testing in steroid-resistant nephrotic syndrome: why, who, when and how? by Preston, Rebecca, Stuart, Helen M., Lennon, Rachel

“…Steroid-resistant nephrotic syndrome (SRNS) is a common cause of chronic kidney disease in childhood and has a significant risk of rapid progression to…”
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Kidney outcomes for children with lupus nephritis by Oni, Louise, Wright, Rachael D, Marks, Stephen, Beresford, Michael W, Tullus, Kjell

“…Systemic lupus erythematosus is a rare lifelong multi-systemic autoimmune condition. Juvenile-onset SLE (JSLE) is recognized to have a more active disease…”
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Ciliopathies: an expanding disease spectrum by Waters, Aoife M., Beales, Philip L.

“…Ciliopathies comprise a group of disorders associated with genetic mutations encoding defective proteins, which result in either abnormal formation or function…”
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Gut microbiome and kidney disease: a bidirectional relationship by Al Khodor, Souhaila, Shatat, Ibrahim F.

“…Recent technological advances and efforts, including powerful metagenomic and metatranscriptomic analyses, have led to a tremendous growth in our understanding…”
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Be aware of acute kidney injury in critically ill children with COVID-19 by Wang, Xiaowen, Chen, Xingfeng, Tang, Feng, Luo, Wanjun, Fang, Jian, Qi, Chang, Sun, Hua, Xiao, Han, Peng, Xuehua, Shao, Jianbo

“…Background Acute kidney injury (AKI) is a common complication of critically ill adult patients with COVID-19. However, currently, no studies investigate kidney…”
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Genetic causes of hypomagnesemia, a clinical overview by Viering, Daan H. H. M, de Baaij, Jeroen H. F., Walsh, Stephen B., Kleta, Robert, Bockenhauer, Detlef

“…Magnesium is essential to the proper functioning of numerous cellular processes. Magnesium ion (Mg 2+ ) deficits, as reflected in hypomagnesemia, can cause…”
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SARS-CoV-2 infection in Spanish children with chronic kidney pathologies by Melgosa, M., Madrid, A., Alvárez, O., Lumbreras, J., Nieto, F., Parada, E., Perez-Beltrán, V.

“…Background There is little information about Coronavirus Disease 2019 (COVID-19) in children with underlying chronic renal pathologies. Cases report From March…”
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New insights into the pathogenesis of IgA nephropathy by Yeo, See Cheng, Cheung, Chee Kay, Barratt, Jonathan

“…IgA nephropathy is the most common form of glomerulonephritis in many parts of the world and remains an important cause of end-stage renal disease. Current…”
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Phosphate homeostasis and its role in bone health by Penido, Maria Goretti M. G., Alon, Uri S.

“…Phosphate is one of the most abundant minerals in the body, and its serum levels are regulated by a complex set of processes occurring in the intestine,…”
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