Search Results - "PEDERSEN, Bjørn Panyella"

Namdinator - automatic molecular dynamics flexible fitting of structural models into cryo-EM and crystallography experimental maps by Kidmose, Rune Thomas, Juhl, Jonathan, Nissen, Poul, Boesen, Thomas, Karlsen, Jesper Lykkegaard, Pedersen, Bjørn Panyella

“…Model building into experimental maps is a key element of structural biology, but can be both time consuming and error prone for low-resolution maps. Here we…”
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Crystal structure of a copper-transporting PIB-type ATPase by Gourdon, Pontus, Liu, Xiang-Yu, Skjørringe, Tina, Morth, J. Preben, Møller, Lisbeth Birk, Pedersen, Bjørn Panyella, Nissen, Poul

“…Heavy-metal homeostasis and detoxification is crucial for cell viability. P-type ATPases of the class IB (PIB) are essential in these processes, actively…”
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Structural basis for alternating access of a eukaryotic calcium/proton exchanger by Waight, Andrew B., Pedersen, Bjørn Panyella, Schlessinger, Avner, Bonomi, Massimiliano, Chau, Bryant H., Roe-Zurz, Zygy, Risenmay, Aaron J., Sali, Andrej, Stroud, Robert M.

“…The X-ray crystal structure of a member of the Ca 2+ /H + (CAX) antiporter family from Saccharomyces cerevisiae in a cytosol-facing, substrate-bound…”
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HiLiDeSystematic Approach to Membrane Protein Crystallization in Lipid and Detergent by Gourdon, Pontus, Andersen, Jacob Lauwring, Hein, Kim Langmach, Bublitz, Maike, Pedersen, Bjørn Panyella, Liu, Xiang-Yu, Yatime, Laure, Nyblom, Maria, Nielsen, Thorbjørn Terndrup, Olesen, Claus, Møller, Jesper Vuust, Nissen, Poul, Morth, Jens Preben

“…To obtain the initial crystallization hit and the subsequent optimization remain the major bottlenecks in membrane protein structure determination. Here we…”
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Structures and mechanism of the plant PIN-FORMED auxin transporter by Ung, Kien Lam, Winkler, Mikael, Schulz, Lukas, Kolb, Martina, Janacek, Dorina P., Dedic, Emil, Stokes, David L., Hammes, Ulrich Z., Pedersen, Bjørn Panyella

“…Auxins are hormones that have central roles and control nearly all aspects of growth and development in plants 1 – 3 . The proteins in the PIN-FORMED (PIN)…”
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Structural Insight into Eukaryotic Sterol Transport through Niemann-Pick Type C Proteins by Winkler, Mikael B.L., Kidmose, Rune T., Szomek, Maria, Thaysen, Katja, Rawson, Shaun, Muench, Stephen P., Wüstner, Daniel, Pedersen, Bjørn Panyella

“…Niemann-Pick type C (NPC) proteins are essential for sterol homeostasis, believed to drive sterol integration into the lysosomal membrane before redistribution…”
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Crystal structure of the plant symporter STP10 illuminates sugar uptake mechanism in monosaccharide transporter superfamily by Paulsen, Peter Aasted, Custódio, Tânia F., Pedersen, Bjørn Panyella

“…Plants are dependent on controlled sugar uptake for correct organ development and sugar storage, and apoplastic sugar depletion is a defense strategy against…”
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Conformational changes in the Niemann-Pick type C1 protein NCR1 drive sterol translocation by Frain, Kelly M, Dedic, Emil, Nel, Lynette, Bohush, Anastasiia, Olesen, Esben, Thaysen, Katja, Wüstner, Daniel, Stokes, David L, Pedersen, Bjørn Panyella

“…The membrane protein Niemann-Pick type C1 (NPC1, named NCR1 in yeast) is central to sterol homeostasis in eukaryotes. NCR1 is localized to the vacuolar…”
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Slow release of a synthetic auxin induces formation of adventitious roots in recalcitrant woody plants by Roth, Ohad, Yechezkel, Sela, Serero, Ori, Eliyahu, Avi, Vints, Inna, Tzeela, Pan, Carignano, Alberto, Janacek, Dorina P., Peters, Verena, Kessel, Amit, Dwivedi, Vikas, Carmeli-Weissberg, Mira, Shaya, Felix, Faigenboim-Doron, Adi, Ung, Kien Lam, Pedersen, Bjørn Panyella, Riov, Joseph, Klavins, Eric, Dawid, Corinna, Hammes, Ulrich Z., Ben-Tal, Nir, Napier, Richard, Sadot, Einat, Weinstain, Roy

“…Clonal propagation of plants by induction of adventitious roots (ARs) from stem cuttings is a requisite step in breeding programs. A major barrier exists for…”
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Crystal structure of the potassium-importing KdpFABC membrane complex by Huang, Ching-Shin, Pedersen, Bjørn Panyella, Stokes, David L.

“…The crystal structure of the bacterial potassium import complex KdpFABC shows how ATP hydrolysis is coupled to potassium transport to maintain cellular…”
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An Intracellular Pathway Controlled by the N-terminus of the Pump Subunit Inhibits the Bacterial KdpFABC Ion Pump in High K+ Conditions by Dubey, Vikas, Stokes, David L., Pedersen, Bjørn Panyella, Khandelia, Himanshu

“…[Display omitted] •Phosphorylation of the TGES motif regulates the ion-transporting protein KdpFABC.•Our MD simulations show that phosphorylation hydrates the…”
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Mechanistic Insight into Lipid Binding to Yeast Niemann Pick Type C2 Protein by Moesgaard, Laust, Petersen, Daniel, Szomek, Maria, Reinholdt, Peter, Winkler, Mikael B. L, Frain, Kelly May, Müller, Peter, Pedersen, Bjørn Panyella, Kongsted, Jacob, Wüstner, Daniel

“…Niemann Pick type C2 (NPC2) is a small sterol binding protein in the lumen of late endosomes and lysosomes. We showed recently that the yeast homologue of NPC2…”
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Structural comparison of GLUT1 to GLUT3 reveal transport regulation mechanism in sugar porter family by Custódio, Tânia Filipa, Paulsen, Peter Aasted, Frain, Kelly May, Pedersen, Bjørn Panyella

“…The human glucose transporters GLUT1 and GLUT3 have a central role in glucose uptake as canonical members of the Sugar Porter (SP) family. GLUT1 and GLUT3…”
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Structure and Function of Auxin Transporters by Hammes, Ulrich Z, Pedersen, Bjørn Panyella

“…Auxins, a group of central hormones in plant growth and development, are transported by a diverse range of transporters with distinct biochemical and…”
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May the proton motive force be with you: A plant transporter review by Andersen, Camilla Gottlieb, Bavnhøj, Laust, Pedersen, Bjørn Panyella

“…As our ecosystems experience challenges associated with climate change, an improved understanding of the fundamental biochemical processes governing plant…”
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Substrate recognition and transport mechanism of the PIN-FORMED auxin exporters by Ung, Kien Lam, Schulz, Lukas, Stokes, David L., Hammes, Ulrich Z., Pedersen, Bjørn Panyella

“…Auxins are a group of pivotal hormones that regulate almost all aspects of plant growth, and synthetic auxin herbicides are broadly used in agriculture…”
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Auxin transport at the endoplasmic reticulum: roles and structural similarity of PIN-FORMED and PIN-LIKES by Ung, Kien Lam, Schulz, Lukas, Kleine-Vehn, Jürgen, Pedersen, Bjørn Panyella, Hammes, Ulrich Z

“…Auxin is a crucial plant hormone that controls a multitude of developmental processes. The directional movement of auxin between cells is largely facilitated…”
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Expression strategies for structural studies of eukaryotic membrane proteins by Lyons, Joseph A, Shahsavar, Azadeh, Paulsen, Peter Aasted, Pedersen, Bjørn Panyella, Nissen, Poul

“…•A table of eukaryotic membrane protein structures reveal expression strategies.•Native sources remain important, but most structures result from heterologous…”
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Sterol uptake by the NPC system in eukaryotes: a Saccharomyces cerevisiae perspective by Winkler, Mikael B. L., Nel, Lynette, Frain, Kelly M., Dedic, Emil, Olesen, Esben, Pedersen, Bjørn Panyella

“…Sterols are an essential component of membranes in all eukaryotic cells and the precursor of multiple indispensable cellular metabolites. After endocytotic…”
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Membrane proteins — do we catch up with the breathless pace of soluble protein structural biology? by Pedersen, Bjørn Panyella, Nissen, Poul

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