Search Results - "PEDERSEN, Bente K"

The diseasome of physical inactivity – and the role of myokines in muscle–fat cross talk by Pedersen, Bente K.

“…Type 2 diabetes, cardiovascular diseases, colon cancer, breast cancer, dementia and depression constitute a cluster of diseases, which defines ‘a diseasome of…”
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Molecular Mechanisms Linking Exercise to Cancer Prevention and Treatment by Hojman, Pernille, Gehl, Julie, Christensen, Jesper F., Pedersen, Bente K.

“…The benefits of exercise training for cancer patients are becoming increasingly evident. Physical exercise has been shown to reduce cancer incidence and…”
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Exercise as an anti-inflammatory therapy for rheumatic diseases—myokine regulation by Benatti, Fabiana B., Pedersen, Bente K.

“…Key Points Persistent systemic inflammation is a typical feature of inflammatory rheumatic diseases such as rheumatoid arthritis and systemic lupus…”
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Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6 by Pedersen, Bente K, Febbraio, Mark A

“…The Centre of Inflammation and Metabolism at Department of Infectious Diseases, and Copenhagen Muscle Research Centre, Rigshospitalet, The Faculty of Health…”
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Edward F. Adolph Distinguished Lecture: Muscle as an endocrine organ: IL-6 and other myokines by Pedersen, Bente K

“…The Centre of Inflammation and Metabolism at the Department of Infectious Diseases, and Copenhagen Muscle Research Centre, Rigshospitalet, the Faculty of…”
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Voluntary Running Suppresses Tumor Growth through Epinephrine- and IL-6-Dependent NK Cell Mobilization and Redistribution by Pedersen, Line, Idorn, Manja, Olofsson, Gitte H., Lauenborg, Britt, Nookaew, Intawat, Hansen, Rasmus Hvass, Johannesen, Helle Hjorth, Becker, Jürgen C., Pedersen, Katrine S., Dethlefsen, Christine, Nielsen, Jens, Gehl, Julie, Pedersen, Bente K., thor Straten, Per, Hojman, Pernille

“…Regular exercise reduces the risk of cancer and disease recurrence. Yet the mechanisms behind this protection remain to be elucidated. In this study,…”
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Interleukin‐6 myokine signaling in skeletal muscle: a double‐edged sword? by Muñoz‐Cánoves, Pura, Scheele, Camilla, Pedersen, Bente K., Serrano, Antonio L.

“…Interleukin (IL)‐6 is a cytokine with pleiotropic functions in different tissues and organs. Skeletal muscle produces and releases significant levels of IL‐6…”
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The miRNA plasma signature in response to acute aerobic exercise and endurance training by Nielsen, Søren, Åkerström, Thorbjörn, Rinnov, Anders, Yfanti, Christina, Scheele, Camilla, Pedersen, Bente K, Laye, Matthew J

“…MiRNAs are potent intracellular posttranscriptional regulators and are also selectively secreted into the circulation in a cell-specific fashion. Global…”
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The Role of Exercise-Induced Myokines in Muscle Homeostasis and the Defense against Chronic Diseases by Brandt, Claus, Pedersen, Bente Klarlund

“…Chronic inflammation is involved in the pathogenesis of insulin resistance, atherosclerosis, neurodegeneration, and tumour growth. Regular exercise offers…”
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Exercise-Induced Catecholamines Activate the Hippo Tumor Suppressor Pathway to Reduce Risks of Breast Cancer Development by Dethlefsen, Christine, Hansen, Louise S, Lillelund, Christian, Andersen, Christina, Gehl, Julie, Christensen, Jesper F, Pedersen, Bente K, Hojman, Pernille

“…Strong epidemiologic evidence documents the protective effect of physical activity on breast cancer risk, recurrence, and mortality, but the underlying…”
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Gut microbiota in human adults with type 2 diabetes differs from non-diabetic adults by Larsen, Nadja, Vogensen, Finn K, van den Berg, Frans W J, Nielsen, Dennis Sandris, Andreasen, Anne Sofie, Pedersen, Bente K, Al-Soud, Waleed Abu, Sørensen, Søren J, Hansen, Lars H, Jakobsen, Mogens

“…Recent evidence suggests that there is a link between metabolic diseases and bacterial populations in the gut. The aim of this study was to assess the…”
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Beneficial health effects of exercise – the role of IL-6 as a myokine by Pedersen, Bente K, Fischer, Christian P

“…It is not clear how contracting skeletal muscles mediate the numerous and diverse metabolic and physiological effects that are beneficial for health…”
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Evidence for a release of brain-derived neurotrophic factor from the brain during exercise by Rasmussen, Peter, Brassard, Patrice, Adser, Helle, Pedersen, Martin V., Leick, Lotte, Hart, Emma, Secher, Niels H., Pedersen, Bente K., Pilegaard, Henriette

“…Brain-derived neurotrophic factor (BDNF) has an important role in regulating maintenance, growth and survival of neurons. However, the main source of…”
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Circulating Follistatin Is Liver-Derived and Regulated by the Glucagon-to-Insulin Ratio by Hansen, Jakob S, Rutti, Sabine, Arous, Caroline, Clemmesen, Jens O, Secher, Niels H, Drescher, Andrea, Gonelle-Gispert, Carmen, Halban, Philippe A, Pedersen, Bente K, Weigert, Cora, Bouzakri, Karim, Plomgaard, Peter

“…Context: Follistatin is a plasma protein recently reported to increase under conditions with negative energy balance, such as exercise and fasting in humans…”
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IL-6 selectively stimulates fat metabolism in human skeletal muscle by Wolsk, Emil, Mygind, Helene, Grøndahl, Thomas S, Pedersen, Bente K, van Hall, Gerrit

“…Interleukin (IL)-6 is chronically elevated in type 2 diabetes but also during exercise. However, the exact metabolic role, and hence the physiological…”
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IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin by Nemeth, Elizabeta, Rivera, Seth, Gabayan, Victoria, Keller, Charlotte, Taudorf, Sarah, Pedersen, Bente K, Ganz, Tomas

“…Hypoferremia is a common response to systemic infections or generalized inflammatory disorders. In mouse models, the development of hypoferremia during…”
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Body Composition Is the Main Determinant for the Difference in Type 2 Diabetes Pathophysiology Between Japanese and Caucasians by MØLLER, Jonas B, PEDERSEN, Maria, UEKI, Kohjiro, INGWERSEN, Steen H, PEDERSEN, Bente K, KADOWAKI, Takashi, TANAKA, Haruhiko, OHSUGI, Mitsuru, OVERGAARD, Rune V, LYNGE, Jan, ALMIND, Katrine, VASCONCELOS, Nina-Maria, POULSEN, Pernille, KELLER, Charlotte

“…OBJECTIVE This cross-sectional clinical study compared the pathophysiology of type 2 diabetes in Japanese and Caucasians and investigated the role of…”
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Ramadan model of intermittent fasting for 28 d had no major effect on body composition, glucose metabolism, or cognitive functions in healthy lean men by Harder-Lauridsen, Nina M., M.D, Rosenberg, Astrid, M.D, Benatti, Fabiana B., Ph.D, Damm, Julie A., M.D, Thomsen, Carsten, M.D., D.M.Sc, Mortensen, Erik L., M.Sc, Pedersen, Bente K., M.D., D.M.Sc, Krogh-Madsen, Rikke, M.D., Ph.D

“…Abstract Objectives There has been a parallel increase in the incidence of obesity and diabetes as well as the number of daily meals. However, evidence is…”
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A 2-wk reduction of ambulatory activity attenuates peripheral insulin sensitivity by KROGH-MADSEN, Rikke, THYFAULT, John P, BROHOLM, Christa, HARTVIG MORTENSEN, Ole, OLDEN, Rasmus H, MOUNIER, Remi, PLOMGAARD, Peter, VAN HALL, Gerrit, BOOTH, Frank W, PEDERSEN, Bente K

“…US adults take between approximately 2,000 and approximately 12,000 steps per day, a wide range of ambulatory activity that at the low range could increase…”
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Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase by CAREY, Andrew L, STEINBERG, Gregory R, KEMP, Bruce E, PEDERSEN, Bente K, FEBBRAIO, Mark A, MACAULAY, S. Lance, THOMAS, Walter G, HOLMES, Anna G, RAMM, Georg, PRELOVSEK, Oja, HOHNEN-BEHRENS, Cordula, WATT, Matthew J, JAMES, David E

“…Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase…”
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