Search Results - "PECHERSTORFER, M"
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Oral ibandronate reduces the risk of skeletal complications in breast cancer patients with metastatic bone disease: results from two randomised, placebo-controlled phase III studies
Published in British journal of cancer (22-03-2004)“…Although intravenous (i.v.) bisphosphonates are the standard of care for metastatic bone disease, they are less than ideal for many patients due to…”
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Efficacy and safety of ibandronate in the treatment of hypercalcemia of malignancy: a randomized multicentric comparison to pamidronate
Published in Supportive care in cancer (01-08-2003)“…To compare the efficacy and safety of ibandronate and pamidronate in patients with hypercalcemia of malignancy (HCM). Seventy-two patients with HCM…”
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Renal safety profiles of ibandronate 6 mg infused over 15 and 60 min: a randomized, open-label study
Published in Annals of oncology (01-07-2008)“…Clinical data show that a single, 15-min i.v. infusion of ibandronate 6 mg does not significantly alter renal function. We evaluated the effect on renal…”
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Rapid administration of ibandronate does not affect renal functioning: evidence from clinical studies in metastatic bone disease and hypercalcaemia of malignancy
Published in Supportive care in cancer (01-12-2004)“…Ibandronate is a third-generation aminobisphosphonate that has an excellent safety record in hypercalcaemia of malignancy, and has recently been approved for…”
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Renal safety profile of ibandronate 6mg infused over 15 or 60 min in breast cancer patients with bone metastases
Published in Bone (New York, N.Y.) (01-03-2008)Get full text
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Biochemical Markers of Bone Formation in Patients with Plasma Cell Dyscrasias and Benign Osteoporosis
Published in Clinical chemistry (Baltimore, Md.) (01-04-2001)“…Myeloma-induced bone loss is related to an uncoupling of bone formation and bone resorption. The aim of the present study was to assess the potential clinical…”
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Randomized phase II trial comparing different doses of the bisphosphonate ibandronate in the treatment of hypercalcemia of malignancy
Published in Journal of clinical oncology (01-01-1996)“…To evaluate the hypocalcemic effect and safety of three different doses of the bisphosphonate ibandronate in tumor-associated hypercalcemia, and to identify…”
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Interleukin-6 and tumor necrosis factor α levels after bisphosphonates treatment in vitro and in patients with malignancy
Published in Bone (New York, N.Y.) (01-02-1996)“…Bisphosphonates are potent inhibitors of bone resorption and are widely used in the treatment of bone diseases. One of the side effects of administered…”
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Serum bone sialoprotein as a marker of tumour burden and neoplastic bone involvement and as a prognostic factor in multiple myeloma
Published in British journal of cancer (02-02-2001)“…To test the potential of immunoreactive BSP, a non-collagenous bone matrix component, as a clinical guide in patients with plasma cell dyscrasias, serum BSP…”
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Parathyroid hormone-related protein and life expectancy in hypercalcemic cancer patients
Published in The journal of clinical endocrinology and metabolism (01-05-1994)“…We determined the effect of raised serum levels of midregional (53-84) parathyroid hormone-related protein (PTHrP) on life expectancy in 59 cancer patients…”
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Cutaneous Melanoma Metastases
Published in The New England journal of medicine (13-11-1997)“…Figure 1. In 1990, a 55-year-old woman presented with an acral lentiginous melanoma of the left sole. A radical extirpation of the tumor (tumor stage, T2;…”
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Serum Parathyroid Hormone-Related Protein Levels and Response to Bisphosphonate Treatment in Hypercalcemia of Malignancy
Published in The journal of clinical endocrinology and metabolism (01-10-1999)“…The pathogenesis of hypercalcemia of malignancy comprises increased net bone resorption and enhanced renal tubular reabsorption of calcium (Ca). To evaluate…”
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The diagnostic value of urinary pyridinium cross-links of collagen, serum total alkaline phosphatase, and urinary calcium excretion in neoplastic bone disease
Published in The journal of clinical endocrinology and metabolism (01-01-1995)“…Bone metastases strongly affect skeletal metabolism by both their growth and their paracrine activities. However, so far no specific laboratory marker has been…”
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Regional cerebral blood flow in patients suffering from post-traumatic stress disorder
Published in Neuropsychobiology (01-01-2001)“…The aim of the study was to determine whether regional cerebral blood flow in survivors of torture suffering from post-traumatic stress disorder (PTSD)…”
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Parathyroid hormone-related protein (PTHrP) does not regulate 1,25-dihydroxyvitamin D serum levels in hypercalcemia of malignancy
Published in The journal of clinical endocrinology and metabolism (01-03-1993)“…We investigated in humoral hypercalcemia of malignancy whether parathyroid hormone-related protein (PTHrP) elevation causes a rise in 1,25-dihydroxyvitamin D…”
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Interphase fluorescence in situ hybridization improves the detection of malignant cells in effusions from breast cancer patients
Published in British journal of cancer (01-01-1997)“…In diagnostic evaluation of effusions, difficulties are encountered when atypical reactive mesothelial cells have to be differentiated from malignant cells. We…”
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Biochemical modulation of 5-fluorouracil by leucovorin with or without interferon-α-2c in patients with advanced colorectal cancer: final results of a randomised phase III study
Published in European journal of cancer (1990) (01-03-1999)“…5-Fluorouracil (5-FU) remains the mainstay of treatment for advanced colorectal carcinoma, although response rates are generally less than 20%. Improved…”
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Myeloma Bone Disease: Update on Pathogenesis and Novel Treatment Strategies
Published in Pharmaceutics (24-10-2018)“…Bone disease, including osteolytic lesions and/or osteoporosis, is a common feature of multiple myeloma (MM). The consequences of skeletal involvement are…”
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