Search Results - "PECE, S"
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1
CDK12 promotes tumorigenesis but induces vulnerability to therapies inhibiting folate one-carbon metabolism in breast cancer
Published in Nature communications (12-05-2022)“…Cyclin-dependent kinase 12 (CDK12) overexpression is implicated in breast cancer, but whether it has a primary or only a cooperative tumorigenic role is…”
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2
Alterations of ubiquitin ligases in human cancer and their association with the natural history of the tumor
Published in Oncogene (20-08-2009)“…Protein ubiquitination is critical for many cellular processes, through its ability to regulate protein degradation and various signaling mechanisms. In the…”
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3
Breast cancer metastases are molecularly distinct from their primary tumors
Published in Oncogene (03-04-2008)“…Metastases have been widely thought to arise from rare, selected, mutation-bearing cells in the primary tumor. Recently, however, it has been proposed that…”
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4
In vitro synergistic cytotoxicity of gemcitabine and pemetrexed and pharmacogenetic evaluation of response to gemcitabine in bladder cancer patients
Published in British journal of cancer (07-08-2006)“…The present study was performed to investigate the capability of gemcitabine and pemetrexed to synergistically interact with respect to cytotoxicity and…”
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5
PO-466 PI3K-C2A regulates mitotic spindle assembly and chemotherapy response in breast cancer
Published in ESMO open (01-07-2018)“…IntroductionProper organisation of the mitotic spindle is key to genetic stability but the molecular components of inter-microtubule (MT) bridges that…”
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6
Loss of PTEN expression leading to high Akt activation in human multiple myelomas
Published in Blood (15-11-2000)“…Mouse plasma cell tumor (PCT) and human multiple myeloma (MM) are terminal B-cell malignancies sharing many similarities. Our recent work demonstrated that…”
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7
Genomic characterization of asymptomatic CT-detected lung cancers
Published in Oncogene (03-03-2011)“…Computed tomography (CT) screening of lung cancer allows the detection of early tumors. The objective of our study was to verify whether initial asymptomatic…”
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8
Prognostic implications of NUMB immunoreactivity in salivary gland carcinomas
Published in International journal of immunopathology and pharmacology (01-10-2007)“…The gene numb encodes for a protein (Numb) involved in cell fate decisions in Drosophila, with proposed endocytic and developmental functions in mammalians…”
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9
Effect of Helicobacter pylori Lipopolysaccharide (LPS) and LPS Derivatives on the Production of Tissue Factor and Plasminogen Activator Inhibitor Type 2 by Human Blood Mononuclear Cells
Published in The Journal of infectious diseases (01-12-1996)“…Different Helicobacter pylori lipopolysaccharides (LPSs) and LPS-derivatives were studied for their ability to induce the production of procoagulant activity…”
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10
Loss of Negative Regulation by Numb over Notch Is Relevant to Human Breast Carcinogenesis
Published in The Journal of cell biology (25-10-2004)“…The biological antagonism between Notch and Numb controls the proliferative/differentiative balance in development and homeostasis. Although altered Notch…”
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11
Signaling from E-cadherins to the MAPK Pathway by the Recruitment and Activation of Epidermal Growth Factor Receptors upon Cell-Cell Contact Formation
Published in The Journal of biological chemistry (29-12-2000)“…E-cadherins are well characterized cell surface molecules expressed in epithelial cells, which play a major role in cell adhesion through the establishment of…”
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12
PATHOGENIC MECHANISMS OF BARTONELLA HENSELAE INFECTIONS
Published in The Pediatric infectious disease journal (01-04-1996)Get full text
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13
Helicobacter pylori infection and host cell responses
Published in Immunopharmacology and immunotoxicology (01-11-1999)“…It is well known that Helicobacter pylori is able to colonize the gastric mucosa, causing a chronic and persistent infection with complications, such as peptic…”
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14
Endocytosis and cancer
Published in Current opinion in cell biology (01-04-2004)“…Eukaryotic cells use endocytosis to internalise plasma membrane, surface receptors and their ligands, viruses and various extracellular soluble molecules…”
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15
More on Pathogenesis and Treatment of Septic Shock
Published in European journal of epidemiology (01-09-1992)Get full text
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16
Activation of the protein kinase Akt/PKB by the formation of E-cadherin-mediated cell-cell junctions. Evidence for the association of phosphatidylinositol 3-kinase with the E-cadherin adhesion complex
Published in The Journal of biological chemistry (02-07-1999)“…E-cadherins are surface adhesion molecules localized at the level of adherens junctions, which play a major role in cell adhesiveness by mediating…”
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17
The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor promotes endothelial cell survival through the activation of Akt/protein kinase B
Published in Cancer research (Chicago, Ill.) (15-03-2001)“…The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor (KSHV-GPCR) is a key molecule in the pathogenesis of Kaposi's sarcoma, playing a central…”
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18
Multiple Organ Involvement by Legionella pneumophila: Pathogenic Mechanisms
Published in European journal of epidemiology (01-01-1992)Get full text
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19
Cat-scratch disease in Italy: a serological approach
Published in The New microbiologica (01-07-1994)“…The results of studies on the serologic responses to Afipia felis and Rochalimaea henselae in suspected patients for Cat Scratch Disease (CSD) are illustrated…”
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20
E-cadherin and Hakai: signalling, remodeling or destruction?
Published in Nature cell biology (01-04-2002)Get full text
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