Search Results - "PAZDUR, Mary"

Pilot Study of Vaccination with Recombinant CEA-MUC-1-TRICOM Poxviral-Based Vaccines in Patients with Metastatic Carcinoma by Gulley, James L, Arlen, Philip M, Tsang, Kwong-Yok, Yokokawa, Junko, Palena, Claudia, Poole, Diane J, Remondo, Cinzia, Cereda, Vittore, Jones, Jacquin L, Pazdur, Mary P, Higgins, Jack P, Hodge, James W, Steinberg, Seth M, Kotz, Herbert, Dahut, William L, Schlom, Jeffrey

“…Purpose: Poxviral vectors have a proven safety record and can be used to incorporate multiple transgenes. Prior clinical trials with poxviral vaccines have…”
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Immunologic and prognostic factors associated with overall survival employing a poxviral-based PSA vaccine in metastatic castrate-resistant prostate cancer by Gulley, James L, Arlen, Philip M, Madan, Ravi A, Tsang, Kwong-Yok, Pazdur, Mary P, Skarupa, Lisa, Jones, Jacquin L, Poole, Diane J, Higgins, Jack P, Hodge, James W, Cereda, Vittore, Vergati, Matteo, Steinberg, Seth M, Halabi, Susan, Jones, Elizabeth, Chen, Clara, Parnes, Howard, Wright, John J, Dahut, William L, Schlom, Jeffrey

“…A concurrent multicenter, randomized Phase II trial employing a recombinant poxviral vaccine provided evidence of enhanced median overall survival (OS) (p =…”
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A randomized phase II study of concurrent docetaxel plus vaccine versus vaccine alone in metastatic androgen-independent prostate cancer by ARLEN, Philip M, GULLEY, James L, STEINBERG, Seth M, JONES, Elizabeth, CHEN, Clara, MARTE, Jennifer, SCHLOM, Jeffrey, DAHUT, William, PARKER, Catherine, SKARUPA, Lisa, PAZDUR, Mary, PANICALI, Dennis, BEETHAM, Patricia, TSANG, Kwong Y, GROSENBACH, Douglas W, FELDMAN, Jarett

“…PURPOSE: Docetaxel has activity against androgen-independent prostate cancer and preclinical studies have shown that taxane-based chemotherapy can enhance…”
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Vaccines: An Innovative Approach to Treating Cancer by Pazdur, Mary P, Jones, Jacquin L

“…Recent scientific advances have expanded our understanding of the immune system and its response to malignant cells. Clinical trials are under way that attempt…”
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A Pilot Study of MUC-1/CEA/TRICOM Poxviral-Based Vaccine in Patients with Metastatic Breast and Ovarian Cancer by MOHEBTASH, Mahsa, TSANG, Kwong-Yok, STEINBERG, Seth M, PAZDUR, Mary, RAUCKHORST, Myrna, JONES, Elizabeth C, DAHUT, William L, SCHLOM, Jeffrey, GULLEY, James L, MADAN, Ravi A, HUEN, Ngar-Yee, POOLE, Diane J, JOCHEMS, Caroline, JONES, Jacquin, FERRARA, Theresa, HEERY, Christopher R, ARLEN, Philip M

“…PANVAC is a recombinant poxviral vaccine that contains transgenes for MUC-1, CEA, and 3 T-cell costimulatory molecules. This study was conducted to obtain…”
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Clinical safety of a viral vector based prostate cancer vaccine strategy by Arlen, Philip M, Skarupa, Lisa, Pazdur, Mary, Seetharam, Mahesh, Tsang, Kwong Y, Grosenbach, Douglas W, Feldman, Jarett, Poole, Diane J, Litzinger, Mary, Steinberg, Seth M, Jones, Elizabeth, Chen, Clara, Marte, Jennifer, Parnes, Howard, Wright, John, Dahut, William, Schlom, Jeffrey, Gulley, James L

“…The primary objective of this phase I study was to evaluate the clinical safety of a vaccine using recombinant vaccinia virus (prime) and recombinant fowlpox…”
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Safety profile of poxviral vaccines: NCI experience by Kim, Joseph W., Marte, Jennifer L., Bilusic, Marijo, Singh, Nishith K., Heery, Christopher Ryan, Madan, Ravi Amrit, Pazdur, Mary, McMahon, Sheri, Rauckhorst, Myrna, Schlom, Jeffrey, Gulley, James L.

“…Abstract only 85 Background: Recombinant poxviruses have been developed as therapeutic cancer vaccines. Here, we report the safety data from NCI clinical…”
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Safety profile of recombinant poxviral TRICOM vaccines by Kim, Joseph W., Marte, Jennifer L., Singh, Nishith K., Heery, Christopher Ryan, Madan, Ravi Amrit, Pazdur, Mary, McMahon, Sheri, Rauckhorst, Myrna, Schlom, Jeffrey, Kantoff, Philip W., Gulley, James L.

“…Abstract only e16036 Background: Recombinant (rec) poxviruses have been developed as therapeutic cancer vaccines. A multi-institutional, randomized phase II…”
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A Randomized Phase II Study of Docetaxel Alone or in Combination with PANVAC™-V (Vaccinia) and PANVAC™-F (Fowlpox) in Patients with Metastatic Breast Cancer (NCI 05-C-0229) by Arlen, Philip M., Pazdur, Mary, Skarupa, Lisa, Rauckhorst, Myrna, Gulley, James L.

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A Pilot Study to Evaluate the Safety and Clinical Outcomes of Vaccination with Recombinant CEA-MUC-1-TRICOM (PANVAC) Poxviral-based Vaccines in Patients with Metastatic Carcinoma by Gulley, James L., Arlen, Philip M., Tsang, Kwong-Yok, Yokokawa, Junko, Palena, Claudia, Poole, Diane J., Remondo, Cinzia, Cereda, Vittore, Jones, Jacquin L., Pazdur, Mary P., Higgins, Jack P., Hodge, James W., Steinberg, Seth M., Kotz, Herbert, Dahut, William L., Schlom, Jeffrey

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Phase I Trial of an Enhanced Prostate-Specific Antigen–Based Vaccine and Anti–CTLA-4 Antibody in Patients with Metastatic Androgen-Independent Prostate Cancer by Theoret, Marc R, Arlen, Philip M, Pazdur, Mary, Dahut, William L, Schlom, Jeffrey, Gulley, James L

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