Search Results - "PAULSSON, Y"

Genes associated with telomerase activity levels in esophageal carcinoma cell lines by Bergqvist, M., Brattström, D., Brodin, D., Lindkvist, A., Dahlman-Wright, K., Dreilich, M., Wagenius, G., Paulsson-Karlsson, Y.

“…Telomerase activity levels have been shown to correlate with tumor progression in several malignancies. However, the genetic regulation of telomerase activity…”
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Human Melanoma Cell Lines of Primary and Metastatic Origin Express the Genes Encoding the Chains of Platelet-Derived Growth Factor (PDGF) and Produce a PDGF-Like Growth Factor by Westermark, Bengt, Johnsson, Ann, Paulsson, Ylva, Betsholtz, Christer, Heldin, Carl-Henrik, Herlyn, Meenhard, Rodeck, Ulrich, Koprowski, Hilary

“…Normal human melanocytes and five human melanoma cell lines were analyzed for production of platelet-derived growth factor (PDGF)-like activity. Three of the…”
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Density-dependent inhibition of cell growth by transforming growth factor-beta 1 in normal human fibroblasts by Paulsson, Y, Beckmann, M P, Westermark, B, Heldin, C H

“…We report here that transforming growth factor-beta 1 (TGF-beta 1) inhibits platelet-derived growth factor (PDGF)-induced DNA synthesis in normal human…”
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Regulation of platelet-derived growth factor gene expression by transforming growth factor beta and phorbol ester in human leukemia cell lines by MAKELA, T. P, ALITALO, R, PAULSSON, Y, WESTERMARK, B, HELDIN, C.-H, ALITALO, K

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Growth factors induce early pre‐replicative changes in senescent human fibroblasts by Paulsson, Y., Bywater, M., Pfeifer‐Ohlsson, S., Ohlsson, R., Nilsson, S., Heldin, C.H., Westermark, B., Betsholtz, C.

“…As human fibroblasts in culture senesce their response to platelet‐derived growth factor (PDGF) becomes attenuated. To clarify at which level such cells are…”
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Effects of epidermal growth factor and platelet-derived growth factor on c-fos and c-myc mRNA levels in normal human fibroblasts by Paulsson, Y, Bywater, M, Heldin, C H, Westermark, B

“…The mRNA levels of two proto-oncogenes, c-fos and c-myc, were determined in human foreskin fibroblasts exposed to epidermal growth factor (EGF) or…”
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A retrospective two centre study of Birt-Hogg-Dubé syndrome reveals a pathogenic founder mutation in FLCN in the Swedish population by Lagerstedt-Robinson, Kristina, Baranowska Körberg, Izabella, Tsiaprazis, Stefanos, Björck, Erik, Tham, Emma, Poluha, Anna, Hellström Pigg, Maritta, Paulsson-Karlsson, Ylva, Nordenskjöld, Magnus, Johansson-Soller, Maria, Aravidis, Christos

“…Birt-Hogg-Dube syndrome (BHDS) (MIM: 135150) is a rare autosomal dominant disorder with variable penetrance, caused by pathogenic variants in the FLCN gene…”
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Extended genetic analysis and tumor characteristics in over 4600 women with suspected hereditary breast and ovarian cancer by Öfverholm, Anna, Törngren, Therese, Rosén, Anna, Arver, Brita, Einbeigi, Zakaria, Haraldsson, Karin, Ståhlbom, Anne Kinhult, Kuchinskaya, Ekaterina, Lindblom, Annika, Melin, Beatrice, Paulsson-Karlsson, Ylva, Stenmark-Askmalm, Marie, Tham, Emma, von Wachenfeldt, Anna, Kvist, Anders, Borg, Åke, Ehrencrona, Hans

“…Genetic screening for pathogenic variants (PVs) in cancer predisposition genes can affect treatment strategies, risk prediction and preventive measures for…”
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Whole-Body MRI Surveillance-Baseline Findings in the Swedish Multicentre Hereditary TP53 -Related Cancer Syndrome Study (SWEP53) by Omran, Meis, Tham, Emma, Brandberg, Yvonne, Ahlström, Håkan, Lundgren, Claudia, Paulsson-Karlsson, Ylva, Kuchinskaya, Ekaterina, Silander, Gustav, Rosén, Anna, Persson, Fredrik, Leonhardt, Henrik, Stenmark-Askmalm, Marie, Berg, Johanna, van Westen, Danielle, Bajalica-Lagercrantz, Svetlana, Blomqvist, Lennart

“…A surveillance strategy of the heritable -related cancer syndrome (h rc), commonly referred to as the Li-Fraumeni syndrome (LFS), is studied in a prospective…”
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Telomerase antagonist imetelstat inhibits esophageal cancer cell growth and increases radiation-induced DNA breaks by Wu, Xuping, Smavadati, Shirin, Nordfjäll, Katarina, Karlsson, Krister, Qvarnström, Fredrik, Simonsson, Martin, Bergqvist, Michael, Gryaznov, Sergei, Ekman, Simon, Paulsson-Karlsson, Ylva

“…Telomerase is mainly active in human tumor cells, which provides an opportunity for a therapeutic window on telomerase targeting. We sought to evaluate the…”
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ELEVATED LEVEL OF gas3 GENE EXPRESSION IS CORRELATED WITH G0 GROWTH ARREST IN HUMAN FIBROBLASTS by Karlsson, Christina, Afrakhte, Mozhgan, Westermark, Bengt, Paulsson, Ylva

“…The gas3/PMP22 gene product is a dual function protein, involved in both peripheral nerve myelination and cell proliferation. gas 3/PMP22 is highly expressed…”
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Possible positive autocrine feedback in the prereplicative phase of human fibroblasts by Paulsson, Ylva, Hammacher, Annet, Heldin, Carl-Henrik, Westermark, Bengt

“…The growth of normal diploid fibroblasts is generally thought to be tightly controlled by exogenous growth factors such as platelet-derived growth factor…”
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Age related induction of platelet-derived growth factor A-chain mRNA in normal human fibroblasts by Karlsson, C, Paulsson, Y

“…We have previously found that stimulation of normal neonatal fibroblasts with PDGF or EGF leads to a transient induction of PDGF A-chain mRNA and the synthesis…”
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Density-dependent inhibitory effect of transforming growth factor-beta 1 on human fibroblasts involves the down-regulation of platelet-derived growth factor alpha-receptors by Paulsson, Y, Karlsson, C, Heldin, C H, Westermark, B

“…We have previously found that transforming growth factor-beta 1 (TGF-beta 1) inhibits the mitogenic activity of platelet-derived growth factor (PDGF) in…”
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Interferon-induced sensitization to apoptosis is associated with repressed transcriptional activity of the hTERT promoter in multiple myeloma by Lindkvist, Anna, Ivarsson, Karolina, Jernberg-Wiklund, Helena, Paulsson-Karlsson, Ylva

“…The aim of the present study was to explore hTERT as a target for IFN-induced sensitization to apoptosis in multiple myeloma (MM). IFN-α and IFN-γ…”
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Production of cell‐associated PDGF‐AA by a human sarcoma cell line: evidence for a latent autocrine effect by Afrakhte, Mozhgan, Mistér, Monica, Östman, Arne, Westermark, Bengt, Paulsson, Ylva

“…The alternative splicing of platelet‐derived growth factor A‐chain is known to result in 2 different protein products. One variant is encoded by transcripts…”
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Escape from senescence in hybrid cell clones involves deletions of two regions located on human chromosome 1q by KARLSSON, C, STENMAN, G, VOJTA, P. J, BONGCAM-RUDLOFF, E, BARRETT, J. C, WESTERMARK, B, PAULSSON, Y

“…Human normal cells have been shown to undergo a limited number of cell doublings, a phenomenon termed cellular senescence. Human chromosome 1 has been…”
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Effect on platelet-derived growth factor-induced mitogenesis of double-stranded RNA: evidence for an autocrine growth inhibition mediated by interferon-beta by Forsberg, K, Paulsson, Y, Westermark, B

“…Stimulation of normal human foreskin fibroblasts with platelet-derived growth factor (PDGF) was inhibited by the addition of the synthetic double-stranded RNA…”
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Tumor necrosis factor-induced expression of platelet-derived growth factor A-chain messenger RNA in fibroblasts by Paulsson, Y, Austgulen, R, Hofsli, E, Heldin, C H, Westermark, B, Nissen-Meyer, J

“…Recombinant tumor necrosis factor (rTNF) induced a transient increase in the expression of the PDGF A-chain mRNA in FS-4 fibroblasts, as determined by Northern…”
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Induction of cyclic AMP synthesis by forskolin is followed by a reduction in the expression of c-myc messenger RNA and inhibition of 3H-thymidine incorporation in human fibroblasts by Heldin, N E, Paulsson, Y, Forsberg, K, Heldin, C H, Westermark, B

“…We have studied the effect of increased intracellular levels of cyclic AMP on the growth response to platelet-derived growth factor (PDGF) of human foreskin…”
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