Search Results - "PAULNOCK, D. M"

Regulation of innate and acquired immunity in African trypanosomiasis by MANSFIELD, J. M., PAULNOCK, D. M.

“…SUMMARY African trypanosomes are well known for their ability to avoid immune elimination by switching the immunodominant variant surface glycoprotein (VSG)…”
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Analysis of interferon-gamma-dependent and -independent pathways of macrophage activation by Paulnock, Donna M., Demick, Karen P., Coller, Susan P.

“…Macrophages are a cellular cornerstone of the innate immune response. The outcome of macrophage activity during development of an immune response to microbes…”
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Genetic manipulation of African trypanosomes as a tool to dissect the immunobiology of infection by MANSFIELD, J.M, PAULNOCK, D.M

“…The variant surface glycoprotein (VSG) coat of African trypanosomes exhibits immunobiological functions distinct from its prominent role as a variant surface…”
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Promoter analysis of an interferon-inducible gene associated with macrophage activation by NICOLET, C. M, PAULNOCK, D. M

“…We have investigated the regulation of an activation-associated guanylate-binding protein gene (mGBP-1/mag-1) in murine macrophage cell lines in response to…”
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Modulation of macrophage function by gamma-irradiation. Acquisition of the primed cell intermediate stage of the macrophage tumoricidal activation pathway by Lambert, LE, Paulnock, DM

“…Macrophage activation for tumor cell killing is a multistep pathway in which responsive macrophages interact sequentially with priming and triggering stimuli…”
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Identification and characterization of a new gene family induced during macrophage activation by Wynn, TA, Nicolet, CM, Paulnock, DM

“…In this report, we describe the primary structure and regulation of two novel IFN-gamma-inducible genes expressed during the process of macrophage activation…”
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Signaling pathways initiated in macrophages after engagement of type A scavenger receptors by Coller, Susan P., Paulnock, Donna M.

“…Scavenger receptors are macrophage cell surface molecules associated with endocytic uptake of lipoproteins and binding of microbial ligands. Macrophage class A…”
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Enhancement of monocyte class I and II histocompatibility antigen expression in man by in vivo β-interferon by SPEAR, G. T, PAULNOCK, D. M, JORDAN, R. L, MELTZER, D. M, MERRITT, J A, BORDEN, E. C

“…Changes in monocyte cell-surface markers were assessed during treatment of patients with beta-interferon (beta-IFN). Immediately after isolation monocytes were…”
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Analysis of macrophage activation in African trypanosomiasis by Paulnock, Donna M., Coller, Susan P.

“…African trypanosomes cause a fatal disease of man and animals that ischaracterized by extensive functional, histological, and pathologicalchanges in the…”
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Spectrophotometric determination of oxidative metabolism by Lokuta, M A, Mehring, G H, Paulnock, D M

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Differential modulation of lymphocyte proliferative responses and lymphokine secretion in mice during development of immunity to Chlamydia psittaci by GUAGLIARDI, L. E, BYRNE, G. I, PAULNOCK, D. M

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Differential induction of activation markers in macrophage cell lines by interferon-gamma by Lambert, L E, Paulnock, D M

“…Macrophage cell lines were used in these studies as a model system to dissect the biochemical and functional mosaic of the macrophage activation process. In…”
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Identification and characterization of monoclonal antibodies specific for macrophages at intermediate stages in the tumoricidal activation pathway by Paulnock, DM, Lambert, LE

“…Macrophage activation for tumor cell killing is a multistep pathway in which responsive macrophages interact sequentially with priming and triggering stimuli…”
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Requirement of differentiative signals of both interferon-γ and 1,25-dihydroxyvitamin D3 for induction and secretion of interleukin-1 by HL-60 cells by SPEAR, G. T, PAULNOCK, D. M, HELGESON, D. O, BORDEN, E. C

“…HL-60, a promyelocytic cell line, was treated with both recombinant interferon-gamma (IFN-gamma) and 1,25-(OH)2 vitamin D3 (D3), and the effect on…”
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Macrophage activation by T cells by Paulnock, D M

“…In the past year, the application of biochemical and molecular approaches to the analysis of macrophage activation by T cells has provided new information…”
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The molecular biology of macrophage activation by Paulnock, D M

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Analysis of the IFN-gamma-signaling pathway in macrophages at different stages of maturation by Lucas, D M, Lokuta, M A, McDowell, M A, Doan, J E, Paulnock, D M

“…We previously demonstrated that the macrophage cell lines RAW 264.7 and WEHI-3 exhibit distinct patterns of gene expression in response to IFN-gamma. This…”
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Differential utilization of IFN-gamma-responsive elements in two maturationally distinct macrophage cell lines by McDowell, MA, Lucas, DM, Nicolet, CM, Paulnock, DM

“…We have characterized the transcriptional response to IFN-gamma in two maturationally distinct macrophage populations: the mature RAW 264.7 cell line,…”
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Expression of major histocompatibility complex antigens on macrophages: correlative study using flow cytometry, radioimmunoassay, and colloidal gold immunolabeling by Guagliardi, L E, Paulnock, D M, Albrecht, R M

“…Correlative scanning electron microscopy (SEM), radioimmunoassay (RIA), and flow cytometric analysis were used to characterize levels of class I and class II…”
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In vivo CD40 ligation can induce T cell-independent antitumor effects that involve macrophages by Lum, Hillary D., Buhtoiarov, Ilia N., Schmidt, Brian E., Berke, Gideon, Paulnock, Donna M., Sondel, Paul M., Rakhmilevich, Alexander L.

“…We have previously demonstrated T cell‐independent antitumor and antimetastatic effects of CD40 ligation that involved natural killer (NK) cells. As CD40…”
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