Search Results - "PATTON, Veronica"

Vascular Endothelial Growth Factor C Promotes Ovarian Carcinoma Progression through Paracrine and Autocrine Mechanisms by Decio, Alessandra, Taraboletti, Giulia, Patton, Veronica, Alzani, Rachele, Perego, Patrizia, Fruscio, Robert, Jürgensmeier, Juliane M, Giavazzi, Raffaella, Belotti, Dorina

“…Vascular endothelial growth factor C (VEGFC) has been reported to promote tumor progression in several tumor types, mainly through the stimulation of…”
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Long-term adaptation following influenza A virus host shifts results in increased within-host viral fitness due to higher replication rates, broader dissemination within the respiratory epithelium and reduced tissue damage by Amat, Julien A R, Patton, Veronica, Chauché, Caroline, Goldfarb, Daniel, Crispell, Joanna, Gu, Quan, Coburn, Alice M, Gonzalez, Gaelle, Mair, Daniel, Tong, Lily, Martinez-Sobrido, Luis, Marshall, John F, Marchesi, Francesco, Murcia, Pablo R

“…The mechanisms and consequences of genome evolution on viral fitness following host shifts are poorly understood. In addition, viral fitness -the ability of an…”
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PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer by Carpinelli, Patrizia, Ceruti, Roberta, Giorgini, Maria Laura, Cappella, Paolo, Gianellini, Laura, Croci, Valter, Degrassi, Anna, Texido, Gemma, Rocchetti, Maurizio, Vianello, Paola, Rusconi, Luisa, Storici, Paola, Zugnoni, Paola, Arrigoni, Claudio, Soncini, Chiara, Alli, Cristina, Patton, Veronica, Marsiglio, Aurelio, Ballinari, Dario, Pesenti, Enrico, Fancelli, Daniele, Moll, Jürgen

“…PHA-739358 is a small-molecule 3-aminopyrazole derivative with strong activity against Aurora kinases and cross-reactivities with some receptor tyrosine…”
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A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity by Ciavolella, Antonella, Rainoldi, Sonia, Isacchi, Antonella, Santocanale, Corrado, Tenca, Pierluigi, Montagnoli, Alessia, Valsasina, Barbara, Brotherton, Deborah, Croci, Valter, Cattoni, Marina, Patton, Veronica, Avanzi, Nilla, Alzani, Rachele, Tibolla, Marcello, Volpi, Daniele, Bensimon, Aaron, Albanese, Clara, Molinari, Antonio, Pesenti, Enrico, Healy, Sandra, Sola, Francesco, Moll, Jurgen, Vanotti, Ermes, Menichincheri, Maria, Marchesi, Vanessa, Fiorentini, Francesco, Ballinari, Dario

“…Cdc7 is an essential kinase that promotes DNA replication by activating origins of replication. Here, we characterized the potent Cdc7 inhibitor PHA-767491 ( 1…”
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The Polo-Like Kinase 1 (PLK1) inhibitor NMS-P937 is effective in a new model of disseminated primary CD56+ acute monoblastic leukaemia by Casolaro, Alessia, Golay, Josee, Albanese, Clara, Ceruti, Roberta, Patton, Veronica, Cribioli, Sabrina, Pezzoni, Alice, Losa, Marco, Texido, Gemma, Giussani, Ursula, Marchesi, Francesco, Amboldi, Nadia, Valsasina, Barbara, Bungaro, Silvia, Cazzaniga, Gianni, Rambaldi, Alessandro, Introna, Martino, Pesenti, Enrico, Alzani, Rachele

“…CD56 is expressed in 15-20% of acute myeloid leukaemias (AML) and is associated with extramedullary diffusion, multidrug resistance and poor prognosis. We…”
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Efficacy of PHA-848125, a Cyclin-Dependent Kinase Inhibitor, on the K-RasG12DLA2 Lung Adenocarcinoma Transgenic Mouse Model: Evaluation by Multimodality Imaging by Degrassi, Anna, Russo, Micaela, Nanni, Cristina, Patton, Veronica, Alzani, Rachele, Giusti, Anna M., Fanti, Stefano, Ciomei, Marina, Pesenti, Enrico, Texido, Gemma

“…Abstract K-ras is the most frequently mutated oncogene in non–small cell lung cancer (NSCLC), the most common form of lung cancer. Recent studies indicate that…”
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Dual targeting of CDK and tropomyosin receptor kinase families by the oral inhibitor PHA-848125, an agent with broad-spectrum antitumor efficacy by Albanese, Clara, Alzani, Rachele, Amboldi, Nadia, Avanzi, Nilla, Ballinari, Dario, Brasca, Maria Gabriella, Festuccia, Claudio, Fiorentini, Francesco, Locatelli, Giuseppe, Pastori, Wilma, Patton, Veronica, Roletto, Fulvia, Colotta, Francesco, Galvani, Arturo, Isacchi, Antonella, Moll, Jurgen, Pesenti, Enrico, Mercurio, Ciro, Ciomei, Marina

“…Altered expression and activity of cyclin-dependent kinase (CDK) and tropomyosin receptor kinase (TRK) families are observed in a wide variety of tumors. In…”
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Phosphorylation of TCTP as a Marker for Polo-like Kinase-1 Activity In Vivo by CUCCHI, Ulisse, GIANELLINI, Laura M, GIORGINI, Maria L, CAPPELLA, Paolo, BERIA, Italo, VALSASINA, Barbara, DE PONTI, Anna, SOLA, Francesco, ALZANI, Rachele, PATTON, Veronica, PEZZONI, Alice, TROIANI, Sonia, SACCARDO, Maria B, RIZZI, Simona

“…Polo-like kinase 1 (PLK1) is the master regulator of mitosis and a target for anticancer therapy. To develop a marker of PLK1 activity in cells and tumour…”
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Efficacy of PHA-848125, a cyclin-dependent kinase inhibitor, on the K-Ras(G12D)LA2 lung adenocarcinoma transgenic mouse model: evaluation by multimodality imaging by Degrassi, Anna, Russo, Micaela, Nanni, Cristina, Patton, Veronica, Alzani, Rachele, Giusti, Anna M, Fanti, Stefano, Ciomei, Marina, Pesenti, Enrico, Texido, Gemma

“…K-ras is the most frequently mutated oncogene in non-small cell lung cancer (NSCLC), the most common form of lung cancer. Recent studies indicate that NSCLC…”
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Abstract A179: NMS-P113, a novel orally available JAK2 selective inhibitor by Gnocchi, Paola, Brasca, Maria Gabriella, Amboldi, Nadia, Avanzi, Nilla, Bindi, Simona, Canevari, Giulia, Casero, Daniele, Ceruti, Roberta, Ciomei, Marina, Cribioli, Sabrina, Cristiani, Cinzia, Nesi, Marcella, Pastori, Wilma, Patton, Veronica, Pellizzoni, Cinzia, Texido, Gemma, Ardini, Elena, Felder, Eduard R., Isacchi, Antonella, Donati, Daniele, Galvani, Arturo

“…Abstract The Janus Kinases (JAK1, JAK2, JAK3, TYK2) are non-receptor tyrosine kinases that play important roles in hematopoiesis and immune response. In…”
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The Polo-Like Kinase 1 by Casolaro, Alessia, Golay, Josee, Albanese, Clara, Ceruti, Roberta, Patton, Veronica, Cribioli, Sabrina, Pezzoni, Alice, Losa, Marco, Texido, Gemma, Giussani, Ursula, Marchesi, Francesco, Amboldi, Nadia, Valsasina, Barbara, Bungaro, Silvia, Cazzaniga, Gianni, Rambaldi, Alessandro, Introna, Martino, Pesenti, Enrico, Alzani, Rachele

“…CD56 is expressed in 15-20% of acute myeloid leukaemias (AML) and is associated with extramedullary diffusion, multidrug resistance and poor prognosis. We…”
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The Polo-Like Kinase 1 Inhibitor NMS-P937 Is Effective in a New Model of Disseminated Primary CD56.sup.+ Acute Monoblastic Leukaemia by Casolaro, Alessia, Golay, Josee, Albanese, Clara, Ceruti, Roberta, Patton, Veronica, Cribioli, Sabrina, Pezzoni, Alice, Losa, Marco, Texido, Gemma, Giussani, Ursula, Marchesi, Francesco, Amboldi, Nadia, Valsasina, Barbara, Bungaro, Silvia, Cazzaniga, Gianni, Rambaldi, Alessandro, Introna, Ma, Pesenti, Enrico, Alzani, Rachele

“…CD56 is expressed in 15-20% of acute myeloid leukaemias (AML) and is associated with extramedullary diffusion, multidrug resistance and poor prognosis. We…”
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Therapeutic efficacy of the pan-cdk inhibitor PHA-793887 in vitro and in vivo in engraftment and high-burden leukemia models by Alzani, Rachele, Pedrini, Olga, Albanese, Clara, Ceruti, Roberta, Casolaro, Alessia, Patton, Veronica, Colotta, Francesco, Rambaldi, Alessandro, Introna, Martino, Pesenti, Enrico, Ciomei, Marina, Golay, Josée

“…Objective The aim of the work was to determine and characterize, in vitro and in vivo, the therapeutic activity of PHA-793887, a new potent pan-cdk inhibitor,…”
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Abstract DD01-01: NMS-1116354: More than an inhibitor of Cdc 7 kinase in S-phase by Colotta, Francesco, Moll, Jurgen, Valsasina, Barbara, Vanotti, Ermes, Rainoldi, Sonia, Sola, Francesco, Marchesi, Vanessa, Menichincheri, Maria, Ciavolella, Antonella, Patton, Veronica, Albanese, Clara, Volpi, Daniele, Avanzi, Nilla, Ballinari, Dario, Fiorentini, Francesco, Isacchi, Antonella, Pesenti, Enrico, Galvani, Arturo, Santocanale, Corrado, Montagnoli, Alessia

“…Abstract Most of the widely used anticancer drugs target the elongation step of DNA synthesis, either directly, for example by restricting the pool of dNTPs or…”
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The Polo-Like Kinase 1 (PLK1) Inhibitor NMS-P937 Is Effective in a New Model of Disseminated Primary CD56+ Acute Monoblastic Leukaemia. e58424 by Casolaro, Alessia, Golay, Josee, Albanese, Clara, Ceruti, Roberta, Patton, Veronica, Cribioli, Sabrina, Pezzoni, Alice, Losa, Marco, Texido, Gemma, Giussani, Ursula

“…CD56 is expressed in 15-20% of acute myeloid leukaemias (AML) and is associated with extramedullary diffusion, multidrug resistance and poor prognosis. We…”
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Reduced mammary tumor progression in a transgenic mouse model fed an isoflavone-poor soy protein concentrate by Chiesa, Giulia, Rigamonti, Elena, Lovati, Maria R, Disconzi, Emanuela, Soldati, Sabina, Sacco, Maria G, Catò, Enrica Mira, Patton, Veronica, Scanziani, Eugenio, Vezzoni, Paolo, Arnoldi, Anna, Locati, Daniela, Sirtori, Cesare R

“…Dietary exposure to soy has been associated with reduced breast cancer incidence. Soy isoflavones and protein components, such as protease inhibitors and the…”
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Rethinking Equal Protection Doctrine in the Wake of McClesky v. Kemp by Patton, Veronica

“…The equal protection doctrine in the aftermath of the Supreme Court case of "McClesky vs Kemp" in which stark racial disparities in the administration of a…”
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RETHINKING EQUAL PROTECTION DOCTRINE IN THE WAKE OF "MCCLESKY V. KEMP" by Patton, Veronica

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