Search Results - "PATTERSON, Randen L"

INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS AS SIGNAL INTEGRATORS by Patterson, Randen L, Boehning, Darren, Snyder, Solomon H

“…The inositol 1,4,5 trisphosphate (IP 3 ) receptor (IP 3 R) is a Ca 2+ release channel that responds to the second messenger IP 3 . Exquisite modulation of…”
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Cytochrome c binds to inositol (1,4,5) trisphosphate receptors, amplifying calcium-dependent apoptosis by Snyder, Solomon H, Boehning, Darren, Patterson, Randen L, Sedaghat, Leela, Glebova, Natalia O, Kurosaki, Tomohiro

“…Mitochondrial cytochrome c release and inositol (1,4,5) trisphosphate receptor (InsP(3)R)-mediated calcium release from the endoplasmic reticulum mediate…”
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Molecular dynamic simulations reveal the structural determinants of Fatty Acid binding to oxy-myoglobin by Chintapalli, Sree V, Bhardwaj, Gaurav, Patel, Reema, Shah, Natasha, Patterson, Randen L, van Rossum, Damian B, Anishkin, Andriy, Adams, Sean H

“…The mechanism(s) by which fatty acids are sequestered and transported in muscle have not been fully elucidated. A potential key player in this process is the…”
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HSP90 regulates cell survival via inositol hexakisphosphate kinase-2 by Chakraborty, Anutosh, Koldobskiy, Michael A, Sixt, Katherine M, Juluri, Krishna R, Mustafa, Asif K, Snowman, Adele M, van Rossum, Damian B, Patterson, Randen L, Snyder, Solomon H

“…Heat-shock proteins (HSPs) are abundant, inducible proteins best known for their ability to maintain the conformation of proteins and to refold damaged…”
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Towards neuronal organoids: a method for long-term culturing of high-density hippocampal neurons by Todd, George K, Boosalis, Casey A, Burzycki, Aaron A, Steinman, Michael Q, Hester, Lynda D, Shuster, Pete W, Patterson, Randen L

“…One of the goals in neuroscience is to obtain tractable laboratory cultures that closely recapitulate in vivo systems while still providing ease of use in the…”
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Action of TFII-I Outside the Nucleus as an Inhibitor of Agonist-Induced Calcium Entry by Caraveo, Gabriela, van Rossum, Damian B, Patterson, Randen L, Snyder, Solomon H, Desiderio, Stephen

“…TFII-I is a transcription factor and a target of phosphorylation by Bruton's tyrosine kinase. In humans, deletions spanning the TFII-I locus are associated…”
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Requirement of the Inositol Trisphosphate Receptor for Activation of Store-Operated Ca2+Channels by Ma, Hong-Tao, Patterson, Randen L., van Rossum, Damian B., Birnbaumer, Lutz, Mikoshiba, Katsuhiko, Gill, Donald L.

“…The coupling mechanism between endoplasmic reticulum (ER) calcium ion (Ca2+) stores and plasma membrane (PM) store-operated channels (SOCs) is crucial to…”
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A Peptide Inhibitor of Cytochrome c/Inositol 1,4,5-Trisphosphate Receptor Binding Blocks Intrinsic and Extrinsic Cell Death Pathways by Boehning, Darren, van Rossum, Damian B., Patterson, Randen L., Snyder, Solomon H.

“…Apoptotic stimuli augment intracellular calcium concentration through inositol 1,4,5-trisphosphate receptors ( IP3R) on endoplasmic reticulum calcium stores…”
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Conserved GXXXG- and S/T-Like Motifs in the Transmembrane Domains of NS4B Protein Are Required for Hepatitis C Virus Replication by QINGXIA HAN, ALIGO, Jason, MANNA, David, BELTON, Kerry, CHINTAPALLI, Sree V, HONG, Yoojin, PATTERSON, Randen L, VAN ROSSUM, Damian B, KONAN, Kouacou V

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Glutamatergic regulation of serine racemase via reversal of PIP2 inhibition by Mustafa, Asif K, Rossum, Damian B. van, Patterson, Randen L, Maag, David, Ehmsen, Jeffrey T, Gazi, Sadia K, Chakraborty, Anutosh, Barrow, Roxanne K, Amzel, L. Mario, Snyder, Solomon H

“…D-serine is a physiologic coagonist with glutamate at NMDA-subtype glutamate receptors. As D-serine is localized in glia, synaptically released glutamate…”
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Reevaluation of the evolutionary events within recA/RAD51 phylogeny by Chintapalli, Sree V, Bhardwaj, Gaurav, Babu, Jagadish, Hadjiyianni, Loukia, Hong, Yoojin, Todd, George K, Boosalis, Casey A, Zhang, Zhenhai, Zhou, Xiaofan, Ma, Hong, Anishkin, Andriy, van Rossum, Damian B, Patterson, Randen L

“…The recA/RAD51 gene family encodes a diverse set of recombinase proteins that affect homologous recombination, DNA-repair, and genome stability. The recA gene…”
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PKC and PLA2 : Probing the complexities of the calcium network by van Rossum, Damian B, Patterson, Randen L

“…Abstract Lipid signaling and phosphorylation cascades are fundamental to calcium signaling networks. In this review, we will discuss the recent laboratory…”
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Phylogenetic Profiles Reveal Evolutionary Relationships within the "Twilight Zone" of Sequence Similarity by Chang, Gue Su, Hong, Yoojin, Ko, Kyung Dae, Bhardwaj, Gaurav, Holmes, Edward C., Patterson, Randen L., van Rossum, Damian B.

“…Inferring evolutionary relationships among highly divergent protein sequences is a daunting task. In particular, when pairwise sequence alignments between…”
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Predicting protein folds with fold-specific PSSM libraries by Hong, Yoojin, Chintapalli, Sree Vamsee, Ko, Kyung Dae, Bhardwaj, Gaurav, Zhang, Zhenhai, van Rossum, Damian, Patterson, Randen L

“…Accurately assigning folds for divergent protein sequences is a major obstacle to structural studies. Herein, we outline an effective method for fold…”
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RACK1 Binds to Inositol 1,4,5-Trisphosphate Receptors and Mediates Ca2+Release by Patterson, Randen L., van Rossum, Damian B., Barrow, Roxanne K., Snyder, Solomon H.

“…RACK1 is not a G protein but closely resembles the heterotrimeric Gβ-subunit. RACK1 serves as a scaffold, linking protein kinase C to its substrates. We…”
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TRP_2, a Lipid/Trafficking Domain That Mediates Diacylglycerol-induced Vesicle Fusion by van Rossum, Damian B., Oberdick, Daniel, Rbaibi, Youssef, Bhardwaj, Gaurav, Barrow, Roxanne K., Nikolaidis, Nikolas, Snyder, Solomon H., Kiselyov, Kirill, Patterson, Randen L.

“…We recently modeled transient receptor potential (TRP) channels using the Gestalt Domain Detection Algorithm-Basic Local Alignment Tool (GDDA-BLAST), which…”
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Inositol 1,4,5-Trisphosphate Receptor/GAPDH Complex Augments Ca2+Release via Locally Derived NADH by Patterson, Randen L., van Rossum, Damian B., Kaplin, Adam I., Barrow, Roxanne K., Snyder, Solomon H.

“…NADH regulates the release of calcium from the endoplasmic reticulum by modulation of inositol 1,4,5-trisphosphate receptors ( IP3R), accounting for the…”
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PHYRN: a robust method for phylogenetic analysis of highly divergent sequences by Bhardwaj, Gaurav, Ko, Kyung Dae, Hong, Yoojin, Zhang, Zhenhai, Ho, Ngai Lam, Chintapalli, Sree V, Kline, Lindsay A, Gotlin, Matthew, Hartranft, David Nicholas, Patterson, Morgen E, Dave, Foram, Smith, Evan J, Holmes, Edward C, Patterson, Randen L, van Rossum, Damian B

“…Both multiple sequence alignment and phylogenetic analysis are problematic in the "twilight zone" of sequence similarity (≤ 25% amino acid identity). Herein we…”
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DANGER, a Novel Regulatory Protein of Inositol 1,4,5-Trisphosphate-Receptor Activity by van Rossum, Damian B., Patterson, Randen L., Cheung, King-Ho, Barrow, Roxanne K., Syrovatkina, Viktoriya, Gessell, Gregory S., Burkholder, Scott G., Watkins, D.Neil, Foskett, J.Kevin, Snyder, Solomon H.

“…We report the cloning and characterization of DANGER, a novel protein which physiologically binds to inositol 1,4,5-trisphosphate receptors (IP3R). DANGER is a…”
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Agonist-Induced Ca2+Entry Determined by Inositol 1,4,5-Trisphosphate Recognition by van Rossum, Damian B., Patterson, Randen L., Kiselyov, Kirill, Boehning, Darren, Barrow, Roxanne K., Gill, Donald L., Snyder, Solomon H.

“…It has been considered that Ca2+release is the causal trigger for Ca2+entry after receptor activation. In DT40 B cells devoid of inositol 1,4,5-trisphosphate…”
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