Search Results - "PATTERSON, B"

Pharmacological targeting of the unfolded protein response for disease intervention by Hetz, Claudio, Axten, Jeffrey M., Patterson, John B.

“…Accumulation of unfolded proteins at the endoplasmic reticulum (ER) is a salient attribute of many human diseases including obesity, liver disorders, cancer,…”
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Environment-Assisted Speed-up of the Field Evolution in Cavity Quantum Electrodynamics by Cimmarusti, A D, Yan, Z, Patterson, B D, Corcos, L P, Orozco, L A, Deffner, S

“…We measure the quantum speed of the state evolution of the field in a weakly driven optical cavity QED system. To this end, the mode of the electromagnetic…”
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A harmonized atlas of mouse spinal cord cell types and their spatial organization by Russ, Daniel E., Cross, Ryan B. Patterson, Li, Li, Koch, Stephanie C., Matson, Kaya J. E., Yadav, Archana, Alkaslasi, Mor R., Lee, Dylan I., Le Pichon, Claire E., Menon, Vilas, Levine, Ariel J.

“…Single-cell RNA sequencing data can unveil the molecular diversity of cell types. Cell type atlases of the mouse spinal cord have been published in recent…”
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Selecting single cell clustering parameter values using subsampling-based robustness metrics by Patterson-Cross, Ryan B, Levine, Ariel J, Menon, Vilas

“…Generating and analysing single-cell data has become a widespread approach to examine tissue heterogeneity, and numerous algorithms exist for clustering these…”
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IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling by Sheng, Xia, Nenseth, Hatice Zeynep, Qu, Su, Kuzu, Omer F., Frahnow, Turid, Simon, Lukas, Greene, Stephanie, Zeng, Qingping, Fazli, Ladan, Rennie, Paul S., Mills, Ian G., Danielsen, Håvard, Theis, Fabian, Patterson, John B., Jin, Yang, Saatcioglu, Fahri

“…Activation of endoplasmic reticulum (ER) stress/the unfolded protein response (UPR) has been linked to cancer, but the molecular mechanisms are poorly…”
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Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy by Logue, Susan E., McGrath, Eoghan P., Cleary, Patricia, Greene, Stephanie, Mnich, Katarzyna, Almanza, Aitor, Chevet, Eric, Dwyer, Róisín M., Oommen, Anup, Legembre, Patrick, Godey, Florence, Madden, Emma C., Leuzzi, Brian, Obacz, Joanna, Zeng, Qingping, Patterson, John B., Jäger, Richard, Gorman, Adrienne M., Samali, Afshin

“…Triple-negative breast cancer (TNBC) lacks targeted therapies and has a worse prognosis than other breast cancer subtypes, underscoring an urgent need for new…”
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Interactions with iridophores and the tissue environment required for patterning melanophores and xanthophores during zebrafish adult pigment stripe formation by Patterson, Larissa B, Parichy, David M

“…Skin pigment patterns of vertebrates are a classic system for understanding fundamental mechanisms of morphogenesis, differentiation, and pattern formation,…”
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Pigment cell interactions and differential xanthophore recruitment underlying zebrafish stripe reiteration and Danio pattern evolution by Patterson, Larissa B., Bain, Emily J., Parichy, David M.

“…Fishes have diverse pigment patterns, yet mechanisms of pattern evolution remain poorly understood. In zebrafish, Danio rerio , pigment–cell autonomous…”
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Air pollution exposure is associated with the gut microbiome as revealed by shotgun metagenomic sequencing by Fouladi, Farnaz, Bailey, Maximilian J., Patterson, William B., Sioda, Michael, Blakley, Ivory C., Fodor, Anthony A., Jones, Roshonda B., Chen, Zhanghua, Kim, Jeniffer S., Lurmann, Frederick, Martino, Cameron, Knight, Rob, Gilliland, Frank D., Alderete, Tanya L.

“…•Exposure to air pollutants is associated with the composition of the gut microbiome using whole-genome sequencing.•O3 exposure is associated with lower gut…”
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Earliest known Oldowan artifacts at >2.58 Ma from Ledi-Geraru, Ethiopia, highlight early technological diversity by Braun, David R., Aldeias, Vera, Archer, Will, Arrowsmith, J Ramon, Baraki, Niguss, Campisano, Christopher J., Deino, Alan L., DiMaggio, Erin N., Dupont-Nivet, Guillaume, Engda, Blade, Feary, David A., Garello, Dominique I., Kerfelew, Zenash, McPherron, Shannon P., Patterson, David B., Reeves, Jonathan S., Thompson, Jessica C., Reed, Kaye E.

“…The manufacture of flaked stone artifacts represents a major milestone in the technology of the human lineage. Although the earliest production of primitive…”
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Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer by Zhao, Na, Cao, Jin, Xu, Longyong, Tang, Qianzi, Dobrolecki, Lacey E, Lv, Xiangdong, Talukdar, Manisha, Lu, Yang, Wang, Xiaoran, Hu, Dorothy Z, Shi, Qing, Xiang, Yu, Wang, Yunfei, Liu, Xia, Bu, Wen, Jiang, Yi, Li, Mingzhou, Gong, Yingyun, Sun, Zheng, Ying, Haoqiang, Yuan, Bo, Lin, Xia, Feng, Xin-Hua, Hartig, Sean M, Li, Feng, Shen, Haifa, Chen, Yiwen, Han, Leng, Zeng, Qingping, Patterson, John B, Kaipparettu, Benny Abraham, Putluri, Nagireddy, Sicheri, Frank, Rosen, Jeffrey M, Lewis, Michael T, Chen, Xi

“…The unfolded protein response (UPR) is a cellular homeostatic mechanism that is activated in many human cancers and plays pivotal roles in tumor progression…”
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Diet, bite force and skull morphology in the generalist rodent morphotype by Maestri, R., Patterson, B. D., Fornel, R., Monteiro, L. R., Freitas, T. R. O.

“…For many vertebrate species, bite force plays an important functional role. Ecological characteristics of a species' niche, such as diet, are often associated…”
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Exposure to air pollutants and the gut microbiota: a potential link between exposure, obesity, and type 2 diabetes by Bailey, Maximillian J., Naik, Noopur N., Wild, Laura E., Patterson, William B., Alderete, Tanya L.

“…Work has shown that increased exposure to air pollutants independently contributes to obesity and type 2 diabetes risk, yet the exact mechanisms underlying…”
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Benzotriazoles in the Aquatic Environment: a Review of Their Occurrence, Toxicity, Degradation and Analysis by Alotaibi, M. D., McKinley, A. J., Patterson, B. M., Reeder, A. Y.

“…Benzotriazoles (BTs) are an emerging class of environmental pollutants used in a wide range of industrial applications. Benzotriazole (BTri) and…”
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The gut microbiome and inflammation in obsessive‐compulsive disorder patients compared to age‐ and sex‐matched controls: a pilot study by Turna, J., Grosman Kaplan, K., Anglin, R., Patterson, B., Soreni, N., Bercik, P., Surette, M. G., Van Ameringen, M.

“…Objective To compare the gut microbiome profile (by way of taxon analysis and indices of β‐ and α‐diversity) and inflammatory markers (C‐reactive protein…”
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Imaging vascular trauma by Patterson, B. O., Holt, P. J., Cleanthis, M., Tai, N., Carrell, T., Loosemore, T. M.

“…Background: Over the past 50 years the management of vascular trauma has changed from mandatory surgical exploration to selective non‐operative treatment,…”
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Cost-effectiveness of an Adjuvanted Recombinant Zoster Vaccine in older adults in the United States by Curran, D., Patterson, B., Varghese, L., Van Oorschot, D., Buck, P., Carrico, J., Hicks, K., Lee, B., Yawn, B.

“…•In the United States, Herpes Zoster results in $1.3 billion in medical care costs annually.•This burden is projected to rise substantially over the coming…”
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Penetration of tenofovir and emtricitabine in mucosal tissues: implications for prevention of HIV-1 transmission by Patterson, Kristine B, Prince, Heather A, Kraft, Eric, Jenkins, Amanda J, Shaheen, Nicholas J, Rooney, James F, Cohen, Myron S, Kashuba, Angela D M

“…A mainstay of strategies to prevent HIV-1 transmission is to use antiretroviral therapy (ART) for pre-exposure prophylaxis (PrEP). Critical to the design and…”
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Whole genome sequencing and the application of a SNP panel reveal primary evolutionary lineages and genomic variation in the lion (Panthera leo) by Bertola, L D, Vermaat, M, Lesilau, F, Chege, M, Tumenta, P N, Sogbohossou, E A, Schaap, O D, Bauer, H, Patterson, B D, White, P A, de Iongh, H H, Laros, J F J, Vrieling, K

“…Previous phylogeographic studies of the lion (Panthera leo) have improved our insight into the distribution of genetic variation, as well as a revised taxonomy…”
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Thyroid hormone–dependent adult pigment cell lineage and pattern in zebrafish by McMenamin, Sarah K., Bain, Emily J., McCann, Anna E., Patterson, Larissa B., Eom, Dae Seok, Waller, Zachary P., Hamill, James C., Kuhlman, Julie A., Eisen, Judith S., Parichy, David M.

“…Pigment patterns are useful for elucidating fundamental mechanisms of pattern formation and how these mechanisms evolve. In zebrafish, several pigment cell…”
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