Search Results - "PATSOS, Georgios"
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Management of the human mucosal defensive barrier: evidence for glycan legislation
Published in Biological chemistry (01-07-2009)“…The human gastrointestinal barrier comprises several layers which enable protection against the external environment. The mucosal epithelium, lamina propria,…”
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Organized proteomic heterogeneity in colorectal cancer liver metastases and implications for therapies
Published in Hepatology (Baltimore, Md.) (01-03-2014)“…Tumor heterogeneity is a major obstacle for developing effective anticancer treatments. Recent studies have pointed to large stochastic genetic heterogeneity…”
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Sparc-Like Protein 1 Is a New Marker of Human Glioma Progression
Published in Journal of proteome research (05-10-2012)“…High-grade gliomas (glioblastomas) are the most common and deadly brain tumors in adults, currently with no satisfactory treatment available. Apart from de…”
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Differential expression proteomics of human colorectal cancer based on a syngeneic cellular model for the progression of adenoma to carcinoma
Published in Proteomics (Weinheim) (01-01-2010)“…This is the first differential expression proteomics study on a human syngeneic cellular in vitro progression model of the colorectal adenoma-to-carcinoma…”
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O-Glycan inhibitors generate aryl-glycans, induce apoptosis and lead to growth inhibition in colorectal cancer cell lines
Published in Glycobiology (Oxford) (01-04-2009)“…Our studies provide direct evidence that O-glycosylation pathways play a role in the regulation of cell growth through apoptosis and proliferation pathways. A…”
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Restoration of absent in melanoma 2 (AIM2) induces G2/M cell cycle arrest and promotes invasion of colorectal cancer cells
Published in International journal of cancer (15-04-2010)“…Absent in melanoma 2 (AIM2) is a member of the interferon‐inducible HIN‐200 protein family. Recent findings point to a role of AIM2 function in both…”
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Compensation of loss of protein function in microsatellite-unstable colon cancer cells (HCT116): A gene-dependent effect on the cell surface glycan profile
Published in Glycobiology (Oxford) (01-07-2009)“…Tumors that display a high level of microsatellite instability (MSI-H) accumulate somatic frameshift mutations in several genes. The compensation of this loss…”
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Organized proteomic heterogeneity in colorectal cancer liver metastases and implications for therapies: Turtoi et al
Published in Hepatology (Baltimore, Md.) (01-03-2014)Get full text
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High Frequency of LMAN1 Abnormalities in Colorectal Tumors with Microsatellite Instability
Published in Cancer research (Chicago, Ill.) (2009)“…Glycosyl epitopes have been identified as tumor-specific markers in colorectal tumors and various lines of evidence indicate the significance of altered…”
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Differential expression proteomics of human colorectal cancer based on a syngeneic cellular model for the progression of adenoma to carcinoma
Published in Proteomics. Clinical applications (01-09-2010)“…This article was originally published in Proteomics 2010, 10, 194–202, DOI 10.1002/pmic.200900614…”
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