Search Results - "PATNAIK, Akash"

Investigation of electrolyte parameters on the performance of gadolinium-doped ceria–based solid oxide fuel cell: an analytical study by Patnaik, Akash, Sharma, Pankaj

“…An analytical study of the effect of gadolinium-doped ceria (GDC) electrolyte parameters on the output voltage, output power, open circuit no-load voltage, and…”
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Mouse Models for Cancer Immunotherapy Research by Olson, Brian, Li, Yadi, Lin, Yu, Liu, Edison T, Patnaik, Akash

“…Immunotherapy has revolutionized cancer therapy, largely attributed to the success of immune-checkpoint blockade. However, there are subsets of patients across…”
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Non-BRCA DNA Damage Repair Gene Alterations and Response to the PARP Inhibitor Rucaparib in Metastatic Castration-Resistant Prostate Cancer: Analysis From the Phase II TRITON2 Study by Abida, Wassim, Campbell, David, Patnaik, Akash, Shapiro, Jeremy D, Sautois, Brieuc, Vogelzang, Nicholas J, Voog, Eric G, Bryce, Alan H, McDermott, Ray, Ricci, Francesco, Rowe, Julie, Zhang, Jingsong, Piulats, Josep Maria, Fizazi, Karim, Merseburger, Axel S, Higano, Celestia S, Krieger, Laurence E, Ryan, Charles J, Feng, Felix Y, Simmons, Andrew D, Loehr, Andrea, Despain, Darrin, Dowson, Melanie, Green, Foad, Watkins, Simon P, Golsorkhi, Tony, Chowdhury, Simon

“…Genomic alterations in DNA damage repair (DDR) genes other than may confer synthetic lethality with PARP inhibition in metastatic castration-resistant prostate…”
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Targeting Innate Immunity in Cancer Therapy by Rameshbabu, Srikrishnan, Labadie, Brian W, Argulian, Anna, Patnaik, Akash

“…The majority of current cancer immunotherapy strategies target and potentiate antitumor adaptive immune responses. Unfortunately, the efficacy of these…”
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Pan-cancer image-based detection of clinically actionable genetic alterations by Kather, Jakob Nikolas, Heij, Lara R, Grabsch, Heike I, Loeffler, Chiara, Echle, Amelie, Muti, Hannah Sophie, Krause, Jeremias, Niehues, Jan M, Sommer, Kai A J, Bankhead, Peter, Kooreman, Loes F S, Schulte, Jefree J, Cipriani, Nicole A, Buelow, Roman D, Boor, Peter, Ortiz-Brüchle, Nadi-Na, Hanby, Andrew M, Speirs, Valerie, Kochanny, Sara, Patnaik, Akash, Srisuwananukorn, Andrew, Brenner, Hermann, Hoffmeister, Michael, van den Brandt, Piet A, Jäger, Dirk, Trautwein, Christian, Pearson, Alexander T, Luedde, Tom

“…Molecular alterations in cancer can cause phenotypic changes in tumor cells and their micro-environment. Routine histopathology tissue slides - which are…”
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New Strategies in Prostate Cancer: Targeting Lipogenic Pathways and the Energy Sensor AMPK by ZADRA, Giorgia, PRIOLO, Carmen, PATNAIK, Akash, LODA, Massimo

“…Although the role of metabolic syndrome (MS) and a high fat diet in prostate cancer (PCa) risk is still a matter of intense debate, it is becoming increasingly…”
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Metformin Decreases Glucose Oxidation and Increases the Dependency of Prostate Cancer Cells on Reductive Glutamine Metabolism by FENDT, Sarah-Maria, BELL, Eric L, PATNAIK, Akash, BLOUIN, Marie Jose, CANTLEY, Lewis C, GUARENTE, Leonard, BLENIS, John, POLLAK, Michael N, OLUMI, Aria F, VANDER HEIDEN, Matthew G, STEPHANOPOULOS, Gregory, KEIBLER, Mark A, DAVIDSON, Shawn M, WIRTH, Gregory J, FISKE, Brian, MAYERS, Jared R, SCHWAB, Matthias, BELLINGER, Gary, CSIBI, Alfredo

“…Metformin inhibits cancer cell proliferation, and epidemiology studies suggest an association with increased survival in patients with cancer taking metformin;…”
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The APL paradigm and the "co-clinical trial" project by Nardella, Caterina, Lunardi, Andrea, Patnaik, Akash, Cantley, Lewis C, Pandolfi, Pier Paolo

“…Tremendous advances in technologies have allowed the attainment of powerful insights into the molecular and genetic determinants that drive human cancers…”
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A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer by Lunardi, Andrea, Ala, Ugo, Epping, Mirjam T, Salmena, Leonardo, Clohessy, John G, Webster, Kaitlyn A, Wang, Guocan, Mazzucchelli, Roberta, Bianconi, Maristella, Stack, Edward C, Lis, Rosina, Patnaik, Akash, Cantley, Lewis C, Bubley, Glenn, Cordon-Cardo, Carlos, Gerald, William L, Montironi, Rodolfo, Signoretti, Sabina, Loda, Massimo, Nardella, Caterina, Pandolfi, Pier Paolo

“…Pier Paolo Pandolfi and colleagues report that compound loss of Pten with Zbtb7a or Trp53 leads to de novo resistance to androgen deprivation therapy in…”
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Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity by Patnaik, Akash, Swanson, Kenneth D, Csizmadia, Eva, Solanki, Aniruddh, Landon-Brace, Natalie, Gehring, Marina P, Helenius, Katja, Olson, Brian M, Pyzer, Athalia R, Wang, Lily C, Elemento, Olivier, Novak, Jesse, Thornley, Thomas B, Asara, John M, Montaser, Laleh, Timmons, Joshua J, Morgan, Todd M, Wang, Yugang, Levantini, Elena, Clohessy, John G, Kelly, Kathleen, Pandolfi, Pier Paolo, Rosenblatt, Jacalyn M, Avigan, David E, Ye, Huihui, Karp, Jeffrey M, Signoretti, Sabina, Balk, Steven P, Cantley, Lewis C

“…Several kinase inhibitors that target aberrant signaling pathways in tumor cells have been deployed in cancer therapy. However, their impact on the tumor…”
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Antihistamine Drug Ebastine Inhibits Cancer Growth by Targeting Polycomb Group Protein EZH2 by Li, Qiaqia, Liu, Kilia Y, Liu, Qipeng, Wang, Guangyu, Jiang, Weihua, Meng, Qingshu, Yi, Yang, Yang, Yongyong, Wang, Rui, Zhu, Sen, Li, Chao, Wu, Longxiang, Zhao, Dongyu, Yan, Lin, Zhang, Lili, Kim, Jung-Sun, Zu, Xiongbing, Kozielski, Anthony J, Qian, Wei, Chang, Jenny C, Patnaik, Akash, Chen, Kaifu, Cao, Qi

“…Enhancer of zester homolog 2 (EZH2), a histone lysine methyltransferase and the catalytic component of polycomb repressive complex 2, has been extensively…”
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ErbB2 Signaling Increases Androgen Receptor Expression in Abiraterone-Resistant Prostate Cancer by Gao, Shuai, Ye, Huihui, Gerrin, Sean, Wang, Hongyun, Sharma, Ankur, Chen, Sen, Patnaik, Akash, Sowalsky, Adam G, Voznesensky, Olga, Han, Wanting, Yu, Ziyang, Mostaghel, Elahe A, Nelson, Peter S, Taplin, Mary-Ellen, Balk, Steven P, Cai, Changmeng

“…ErbB2 signaling appears to be increased and may enhance androgen receptor (AR) activity in a subset of patients with castration-resistant prostate cancer…”
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Vulnerabilities of PTEN-TP53-deficient prostate cancers to compound PARP-PI3K inhibition by González-Billalabeitia, Enrique, Seitzer, Nina, Song, Su Jung, Song, Min Sup, Patnaik, Akash, Liu, Xue-Song, Epping, Mirjam T, Papa, Antonella, Hobbs, Robin M, Chen, Ming, Lunardi, Andrea, Ng, Christopher, Webster, Kaitlyn A, Signoretti, Sabina, Loda, Massimo, Asara, John M, Nardella, Caterina, Clohessy, John G, Cantley, Lewis C, Pandolfi, Pier Paolo

“…Prostate cancer is the most prevalent cancer in males, and treatment options are limited for advanced forms of the disease. Loss of the PTEN and TP53 tumor…”
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Perspectives in immunotherapy: meeting report from the immunotherapy bridge (December 2nd–3rd, 2020, Italy) by Ascierto, Paolo A, Bifulco, Carlo, Ciardiello, Fortunato, Demaria, Sandra, Emens, Leisha A, Ferris, Robert, Formenti, Silvia C, Galon, Jerome, Khleif, Samir N, Kirchhoff, Tomas, McQuade, Jennifer, Odunsi, Kunle, Patnaik, Akash, Paulos, Chrystal M, Taube, Janis M, Timmerman, John, Fox, Bernard A, Hwu, Patrick, Puzanov, Igor

“…Abstract Improved understanding of tumor immunology has enabled the development of therapies that harness the immune system and prevent immune escape. Numerous…”
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Perspectives in immunotherapy: meeting report from the "Immunotherapy Bridge" (December 4th-5th, 2019, Naples, Italy) by Ascierto, Paolo A, Butterfield, Lisa H, Campbell, Katie, Daniele, Bruno, Dougan, Michael, Emens, Leisha A, Formenti, Silvia, Janku, Filip, Khleif, Samir N, Kirchhoff, Tomas, Morabito, Alessandro, Najjar, Yana, Nathan, Paul, Odunsi, Kunle, Patnaik, Akash, Paulos, Chrystal M, Reinfeld, Bradley I, Skinner, Heath D, Timmerman, John, Puzanov, Igor

“…Over the last few years, numerous clinical trials and real-world experience have provided a large amount of evidence demonstrating the potential for long-term…”
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1537 Androgen blockade primes NLRP3 inflammasome in macrophages to induce tumor cell phagocytosis by Chaudagar, Kiranj, Rameshbabu, Srikrishnan, Mei, Shenglin, Hirz, Taghreed, Xia, Zheng, Hu, Ya-Mei, Argulian, Anna, Labadie, Brian, Desai, Kunal, Grimaldo, Sammy, Kahramangil, Doga, Nair, Rishikesh, DSouza, Sabina, Zhou, Dylan, Shafran, Jordan, Sykes, David, Moran, Amy, Patnaik, Akash

“…BackgroundWhile immune-based therapies induce durable remissions in subsets of patients across a wide range of malignancies, efficacy in metastatic…”
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Ubiquitin Is Part of the Retrovirus Budding Machinery by Patnaik, Akash, Chau, Vincent, Wills, John W.

“…Retroviruses contain relatively large amounts of ubiquitin, but the significance of this finding has been unknown. Here, we show that drugs that are known to…”
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Role of Device Parameters in Optimizing 2DEG Charge Density in β-(Al x Ga 1− x ) 2 O 3 /Ga 2 O 3 HFET: An Analytical Approach by Patnaik, Akash, Jaiswal, Neeraj K., Sharma, Pankaj

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Budding of Equine Infectious Anemia Virus Is Insensitive to Proteasome Inhibitors by Patnaik, Akash, Chau, Vincent, Li, Feng, Montelaro, Ronald C, Wills, John W

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Utilizing precision medicine to modulate the prostate tumor microenvironment and enhance immunotherapy by Olson, Brian, Patnaik, Akash

“…The last two decades of cancer research have seen two major advancements in our ability to treat cancer: precision medicine and immunotherapy. While these…”
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