Search Results - "PATKI, Amit"

Genome-wide polygenic score to predict chronic kidney disease across ancestries by Khan, Atlas, Turchin, Michael C., Patki, Amit, Srinivasasainagendra, Vinodh, Shang, Ning, Nadukuru, Rajiv, Jones, Alana C., Malolepsza, Edyta, Dikilitas, Ozan, Kullo, Iftikhar J., Schaid, Daniel J., Karlson, Elizabeth, Ge, Tian, Meigs, James B., Smoller, Jordan W., Lange, Christoph, Crosslin, David R., Jarvik, Gail P., Bhatraju, Pavan K., Hellwege, Jacklyn N., Chandler, Paulette, Torvik, Laura Rasmussen, Fedotov, Alex, Liu, Cong, Kachulis, Christopher, Lennon, Niall, Abul-Husn, Noura S., Cho, Judy H., Ionita-Laza, Iuliana, Gharavi, Ali G., Chung, Wendy K., Hripcsak, George, Weng, Chunhua, Nadkarni, Girish, Irvin, Marguerite R., Tiwari, Hemant K., Kenny, Eimear E., Limdi, Nita A., Kiryluk, Krzysztof

“…Chronic kidney disease (CKD) is a common complex condition associated with high morbidity and mortality. Polygenic prediction could enhance CKD screening and…”
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Longevity is impacted by growth hormone action during early postnatal period by Sun, Liou Y, Fang, Yimin, Patki, Amit, Koopman, Jacob Je, Allison, David B, Hill, Cristal M, Masternak, Michal M, Darcy, Justin, Wang, Jian, McFadden, Samuel, Bartke, Andrzej

“…Life-long lack of growth hormone (GH) action can produce remarkable extension of longevity in mice. Here we report that GH treatment limited to a few weeks…”
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A 6-CpG validated methylation risk score model for metabolic syndrome: The HyperGEN and GOLDN studies by Hidalgo, Bertha A, Minniefield, Bre, Patki, Amit, Tanner, Rikki, Bagheri, Minoo, Tiwari, Hemant K, Arnett, Donna K, Irvin, Marguerite Ryan

“…There has been great interest in genetic risk prediction using risk scores in recent years, however, the utility of scores developed in European populations…”
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Variant level heritability estimates of type 2 diabetes in African Americans by Armstrong, Nicole D., Patki, Amit, Srinivasasainagendra, Vinodh, Ge, Tian, Lange, Leslie A., Kottyan, Leah, Namjou, Bahram, Shah, Amy S., Rasmussen-Torvik, Laura J., Jarvik, Gail P., Meigs, James B., Karlson, Elizabeth W., Limdi, Nita A., Irvin, Marguerite R., Tiwari, Hemant K.

“…Type 2 diabetes (T2D) is caused by both genetic and environmental factors and is associated with an increased risk of cardiorenal complications and mortality…”
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Telomere shortening and the transition to family caregiving in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study by Armstrong, Nicole D, Irvin, Marguerite R, Haley, William E, Blinka, Marcela D, Kamin Mukaz, Debora, Patki, Amit, Rutherford Siegel, Sue, Shalev, Idan, Durda, Peter, Mathias, Rasika A, Walston, Jeremy D, Roth, David L

“…Telomere length (TL) is widely studied as a possible biomarker for stress-related cellular aging and decreased longevity. There have been conflicting findings…”
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The Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet and Metabolites in Chronic Kidney Disease by Couch, Catharine A, Ament, Zsuzsanna, Patki, Amit, Kijpaisalratana, Naruchorn, Bhave, Varun, Jones, Alana C, Armstrong, Nicole D, Cheung, Katharine L, Kimberly, W Taylor, Tiwari, Hemant K, Irvin, Marguerite Ryan

“…The Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) is a hybrid of the Mediterranean and DASH (Dietary Approaches to Stop Hypertension)…”
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Sex-Associated Metabolites and Incident Stroke, Incident Coronary Heart Disease, Hypertension, and Chronic Kidney Disease in the REGARDS Cohort by Couch, Catharine A, Ament, Zsuzsanna, Patki, Amit, Kijpaisalratana, Naruchorn, Bhave, Varun, Jones, Alana C, Armstrong, Nicole D, Cushman, Mary, Kimberly, W Taylor, Irvin, M Ryan

“…Sex disparities exist in cardiometabolic diseases. Metabolomic profiling offers insight into disease mechanisms, as the metabolome is influenced by…”
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A methylation risk score for chronic kidney disease: a HyperGEN study by Jones, Alana C., Patki, Amit, Srinivasasainagendra, Vinodh, Hidalgo, Bertha A., Tiwari, Hemant K., Limdi, Nita A., Armstrong, Nicole D., Chaudhary, Ninad S., Minniefield, Bré, Absher, Devin, Arnett, Donna K., Lange, Leslie A., Lange, Ethan M., Young, Bessie A., Diamantidis, Clarissa J., Rich, Stephen S., Mychaleckyj, Josyf C., Rotter, Jerome I., Taylor, Kent D., Kramer, Holly J., Tracy, Russell P., Durda, Peter, Kasela, Silva, Lappalinen, Tuuli, Liu, Yongmei, Johnson, W. Craig, Van Den Berg, David J., Franceschini, Nora, Liu, Simin, Mouton, Charles P., Bhatti, Parveen, Horvath, Steve, Whitsel, Eric A., Irvin, Marguerite R.

“…Chronic kidney disease (CKD) impacts about 1 in 7 adults in the United States, but African Americans (AAs) carry a disproportionately higher burden of disease…”
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Epigenome-wide association study of metabolic syndrome in African-American adults by Akinyemiju, Tomi, Do, Anh N, Patki, Amit, Aslibekyan, Stella, Zhi, Degui, Hidalgo, Bertha, Tiwari, Hemant K, Absher, Devin, Geng, Xin, Arnett, Donna K, Irvin, Marguerite R

“…The high prevalence of obesity among US adults has resulted in significant increases in associated metabolic disorders such as diabetes, dyslipidemia, and high…”
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Metabolite profiles and DNA methylation in metabolic syndrome: a two-sample, bidirectional Mendelian randomization by Jones, Alana C, Ament, Zsuzsanna, Patki, Amit, Chaudhary, Ninad S, Srinivasasainagendra, Vinodh, Kijpaisalratana, Naruchorn, Absher, Devin M, Tiwari, Hemant K, Arnett, Donna K, Kimberly, W Taylor, Irvin, Marguerite R

“…Metabolic syndrome (MetS) increases the risk of cardiovascular disease and death. Previous '-omics' studies have identified dysregulated serum metabolites and…”
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Epigenetic Age Acceleration in Mothers and Offspring 4-10 Years after a Pregnancy Complicated by Gestational Diabetes and Obesity by Kanney, Nita, Patki, Amit, Chandler-Laney, Paula, Garvey, W Timothy, Hidalgo, Bertha A

“…A known association exists between exposure to gestational diabetes mellitus (GDM) and epigenetic age acceleration (EAA) in GDM-exposed offspring compared to…”
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Association of CMV genomic mutations with symptomatic infection and hearing loss in congenital CMV infection by Dobbins, G Clement, Patki, Amit, Chen, Dongquan, Tiwari, Hemant K, Hendrickson, Curtis, Britt, William J, Fowler, Karen, Chen, Jake Y, Boppana, Suresh B, Ross, Shannon A

“…Congenital cytomegalovirus (cCMV) infection is the most common congenital infection and a leading cause of long-term neurological and sensory sequelae, the…”
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Genetic Contributors of Incident Stroke in 10,700 African Americans With Hypertension: A Meta-Analysis From the Genetics of Hypertension Associated Treatments and Reasons for Geographic and Racial Differences in Stroke Studies by Armstrong, Nicole D, Srinivasasainagendra, Vinodh, Patki, Amit, Tanner, Rikki M, Hidalgo, Bertha A, Tiwari, Hemant K, Limdi, Nita A, Lange, Ethan M, Lange, Leslie A, Arnett, Donna K, Irvin, Marguerite R

“…African Americans (AAs) suffer a higher stroke burden due to hypertension. Identifying genetic contributors to stroke among AAs with hypertension is critical…”
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An Amish founder population reveals rare-population genetic determinants of the human lipidome by Montasser, May E., Aslibekyan, Stella, Srinivasasainagendra, Vinodh, Tiwari, Hemant K., Patki, Amit, Bagheri, Minoo, Kind, Tobias, Barupal, Dinesh Kumar, Fan, Sili, Perry, James, Ryan, Kathleen A., Shuldiner, Alan R., Arnett, Donna K., Beitelshees, Amber L., Irvin, Marguerite Ryan, O’Connell, Jeffrey R.

“…Identifying the genetic determinants of inter-individual variation in lipid species (lipidome) may provide deeper understanding and additional insight into the…”
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Neighborhood Walkability as a Predictor of Incident Hypertension in a National Cohort Study by Jones, Alana C, Chaudhary, Ninad S, Patki, Amit, Howard, Virginia J, Howard, George, Colabianchi, Natalie, Judd, Suzanne E, Irvin, Marguerite R

“…The built environment (BE) has been associated with health outcomes in prior studies. Few have investigated the association between neighborhood walkability, a…”
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Genomics of Postprandial Lipidomics in the Genetics of Lipid-Lowering Drugs and Diet Network Study by Irvin, Marguerite R, Montasser, May E, Kind, Tobias, Fan, Sili, Barupal, Dinesh K, Patki, Amit, Tanner, Rikki M, Armstrong, Nicole D, Ryan, Kathleen A, Claas, Steven A, O'Connell, Jeffrey R, Tiwari, Hemant K, Arnett, Donna K

“…Postprandial lipemia (PPL) is an important risk factor for cardiovascular disease. Inter-individual variation in the dietary response to a meal is known to be…”
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Vaccine-Induced Cellular Immune Responses Reduce Plasma Viral Concentrations after Repeated Low-Dose Challenge with Pathogenic Simian Immunodeficiency Virus SIVmac239 by Wilson, Nancy A, Reed, Jason, Napoe, Gnankang S, Piaskowski, Shari, Szymanski, Andy, Furlott, Jessica, Gonzalez, Edna J, Yant, Levi J, Maness, Nicholas J, May, Gemma E, Soma, Taeko, Reynolds, Matthew R, Rakasz, Eva, Rudersdorf, Richard, McDermott, Adrian B, O'Connor, David H, Friedrich, Thomas C, Allison, David B, Patki, Amit, Picker, Louis J, Burton, Dennis R, Lin, Jing, Huang, Lingyi, Patel, Deepa, Heindecker, Gwendolyn, Fan, Jiang, Citron, Michael, Horton, Melanie, Wang, Fubao, Liang, Xiaoping, Shiver, John W, Casimiro, Danilo R, Watkins, David I

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Correction to: Association of CMV genomic mutations with symptomatic infection and hearing loss in congenital CMV infection by Dobbins, G Clement, Patki, Amit, Chen, Dongquan, Tiwari, Hemant K, Hendrickson, Curtis, Britt, William J, Fowler, Karen, Chen, Jake Y, Boppana, Suresh B, Ross, Shannon A

“…After publication of the original article [1], we were notified that Fig. 3 has "Fig. 1" posted on the top of it and Figs. 4 and 5 have "Genomic Position" in a…”
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Whole-Exome Sequencing and hiPSC Cardiomyocyte Models Identify MYRIP , TRAPPC11 , and SLC27A6 of Potential Importance to Left Ventricular Hypertrophy in an African Ancestry Population by Irvin, Marguerite R, Aggarwal, Praful, Claas, Steven A, de las Fuentes, Lisa, Do, Anh N, Gu, C Charles, Matter, Andrea, Olson, Benjamin S, Patki, Amit, Schwander, Karen, Smith, Joshua D, Srinivasasainagendra, Vinodh, Tiwari, Hemant K, Turner, Amy J, Nickerson, Deborah A, Rao, Dabeeru C, Broeckel, Ulrich, Arnett, Donna K

“…: Indices of left ventricular (LV) structure and geometry represent useful intermediate phenotypes related to LV hypertrophy (LVH), a predictor of…”
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Genetic Variation in NCAM1 Contributes to Left Ventricular Wall Thickness in Hypertensive Families by Arnett, Donna K, Meyers, Kristin J, Devereux, Richard B, Tiwari, Hemant K, Gu, Charles C, Vaughan, Laura K, Perry, Rodney T, Patki, Amit, Claas, Steven A, Sun, Yan V, Broeckel, Ulrich, Kardia, Sharon L

“…RATIONALE:Left ventricular (LV) mass and related phenotypes are heritable, important predictors of cardiovascular disease, particularly in hypertensive…”
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