Search Results - "PATIL, Neelakanteshwar K"
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p-Coumaric acid inhibits the Listeria monocytogenes RecA protein functions and SOS response: An antimicrobial target
Published in Biochemical and biophysical research communications (01-10-2019)“…Bacterial RecA plays an important role in the evaluation of antibiotic resistance via stress-induced DNA repair mechanism; SOS response. Accordingly, RecA…”
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Suramin is a potent and selective inhibitor of Mycobacterium tuberculosis RecA protein and the SOS response: RecA as a potential target for antibacterial drug discovery
Published in Journal of antimicrobial chemotherapy (01-07-2014)“…In eubacteria, RecA is essential for recombinational DNA repair and for stalled replication forks to resume DNA synthesis. Recent work has implicated a role…”
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Synergy between the N‐terminal and C‐terminal domains of Mycobacterium tuberculosis HupB is essential for high‐affinity binding, DNA supercoiling and inhibition of RecA‐promoted strand exchange
Published in The FEBS journal (01-09-2011)“…The occurrence of DNA architectural proteins containing two functional domains derived from two different architectural proteins is an interesting emerging…”
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Gallic acid inhibits Staphylococcus aureus RecA protein functions: Role in countering antibiotic resistance in bacteria
Published in Journal of applied microbiology (03-06-2024)“…Recombinase RecA and its homologs play a key role in homologous recombination DNA repair and revive stalled replication fork DNA synthesis. RecA plays an…”
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Characterization of Staphylococcus aureus RecX protein: Molecular insights into negative regulation of RecA protein and implications in HR processes
Published in Journal of biochemistry (Tokyo) (01-09-2023)“…Homologous recombination is essential for genome stability and for maintaining genetic diversity. In eubacteria, RecA protein plays a key role during DNA…”
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Mycobacterium tuberculosis UvrD1 and UvrA Proteins Suppress DNA Strand Exchange Promoted by Cognate and Noncognate RecA Proteins
Published in Biochemistry (Easton) (15-06-2010)“…DNA helicases are present in all kingdoms of life and play crucial roles in processes of DNA metabolism such as replication, repair, recombination, and…”
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Molecular and functional characterization of the Listeria monocytogenes RecA protein: Insights into the homologous recombination process
Published in The international journal of biochemistry & cell biology (01-02-2020)“…[Display omitted] •L. monocytogenes RecA gets expressed more than 2 fold in response to DNA damaging agents MMS and UV.•The purified LmRecA protein catalyses…”
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Expression and Characterization of the Staphylococcus aureus RecA protein: A mapping of canonical functions
Published in Protein expression and purification (01-01-2022)“…Recombinases are responsible for homologous recombination (HR), proper genome maintenance, and accurate deoxyribonucleic acid (DNA) duplication. Moreover, HR…”
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SIRT1/AMPK-mediated pathway: Ferulic acid from sugar beet pulp mitigating obesity-induced diabetes-linked complications and improving metabolic health
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-10-2024)“…Obesity-induced type 2 diabetes (T2D) increases the risk of metabolic syndrome due to the high calorie intake. The role of sugar beet pulp (SBP) in T2D and the…”
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trans‐ferulic acid attenuates hyperglycemia‐induced oxidative stress and modulates glucose metabolism by activating AMPK signaling pathway in vitro
Published in Journal of food biochemistry (01-02-2022)“…Adenosine monophosphate‐activated protein kinase (AMPK) is a potent metabolic regulator and an attractive target for antidiabetic activators. Here we report…”
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Expression, purification and biochemical characterization of Listeria monocytogenes single stranded DNA binding protein 1
Published in Protein expression and purification (01-09-2019)“…Single-stranded DNA binding proteins play an important role in DNA metabolic processes including replication, recombination, and repair. Here, we report the…”
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Mechanical force antagonizes the inhibitory effects of RecX on RecA filament formation in Mycobacterium tuberculosis
Published in Nucleic acids research (29-10-2014)“…Efficient bacterial recombinational DNA repair involves rapid cycles of RecA filament assembly and disassembly. The RecX protein plays a crucial inhibitory…”
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DNA Binding, Coprotease, and Strand Exchange Activities of Mycobacterial RecA Proteins: Implications for Functional Diversity among RecA Nucleoprotein Filaments
Published in Biochemistry (Easton) (18-01-2011)“…One of the fundamental questions concerning homologous recombination is how RecA or its homologues recognize several DNA sequences with high affinity and…”
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Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
Published in Journal of biosciences (01-03-2015)“…Structures of crystals of Mycobacterium tuberculosis RecA, grown and analysed under different conditions, provide insights into hitherto underappreciated…”
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Mycobacterium leprae RecA is structurally analogous but functionally distinct from Mycobacterium tuberculosis RecA protein
Published in Biochimica et biophysica acta (01-12-2011)“…Mycobacterium leprae is closely related to Mycobacterium tuberculosis, yet causes a very different illness. Detailed genomic comparison between these two…”
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Enhanced and potential degradation of o-phthalate by Bacillus sp. immobilized cells in alginate and polyurethane
Published in International biodeterioration & biodegradation (01-03-2006)“…Phthalate is a key metabolite during the degradative pathways of various aromatic compounds, which are generally recognized as pollutants. Bacillus sp. (NCIM…”
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Degradation of Salicylic Acid by Free and Immobilized Cells of Pseudomonas sp. Strain NGK1
Published in Journal of microbiology and biotechnology (01-01-2003)“…A Pseudomonas sp. strain NGK1 (NCIM 5120) capable of utilizing salicylate was immobilized in alginate and polyurethane foam (PUF). The degradation rate of…”
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Degradation of plasticizer di-n-butylphthalate by Delftia sp. TBKNP-05
Published in Current microbiology (01-05-2006)“…Bacterial strain Delftia sp. TBKNP-05, isolated by para-hydroxybenzoate enrichment technique, is capable of degrading di-n-butylphthalate (DBP) as a sole…”
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Degradation of a Plasticizer, di-n-Butylphthalate by Delftia sp. TBKNP-05
Published in Current microbiology (01-03-2006)“…A bacterial strain Delftia sp. TBKNP-05 isolated by para-hydroxybenzoate enrichment technique is capable of degrading di-n-butylphthalate (DBP) as a sole…”
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Parametric studies on batch degradation of a plasticizer di-n-butylphthalate by immobilized Bacillus sp
Published in World journal of microbiology & biotechnology (01-12-2005)“…Di-n-butylphthalate (DBP) is one of the phthalate esters (PAEs) used in the manufacture of plasticizers, insect repellents and synthetic fibres and contributes…”
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