Search Results - "PATIL, Ashok D."

Comparison of biochemical and biological effects of ML858 (salinosporamide A) and bortezomib by Williamson, Mark J, Blank, Jonathan L, Bruzzese, Frank J, Cao, Yueying, Daniels, J Scott, Dick, Lawrence R, Labutti, Jason, Mazzola, Anne M, Patil, Ashok D, Reimer, Corinne L, Solomon, Marjorie S, Stirling, Matthew, Tian, Yuan, Tsu, Christopher A, Weatherhead, Gabriel S, Zhang, Julie X, Rolfe, Mark

“…Strains within the genus Salinospora have been shown to produce complex natural products having antibiotic and antiproliferative activities. The biochemical…”
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Novel Alkaloids from the Sponge Batzella sp.: Inhibitors of HIV gp120-Human CD4 Binding by Patil, Ashok D, Kumar, N. Vasant, Kokke, Wilhelmus C, Bean, Mark F, Freyer, Alan J, Brosse, Charles De, Mai, Shing, Truneh, Alemseged, Carte, Brad

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Synthesis of the tricyclic portions of batzelladines A, B and D. Revision of the stereochemistry of batzelladines A and D by Snider, Barry B, Chen, Jinsheng, Patil, Ashok D, Freyer, Alan J

“…The tricyclic portion 4 of batzelladine B ( 2) is obtained from 10a, which differs in one side chain from the ptilomycalin A model 10c that we prepared several…”
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The inophyllums, novel inhibitors of HIV-1 reverse transcriptase isolated from the Malaysian tree, Calophyllum inophyllum Linn by Patil, Ashok D, Freyer, Alan J, Eggleston, Drake S, Haltiwanger, R. Curtis, Bean, Mark F, Taylor, Paul B, Caranfa, Mary Jo, Breen, Ann L, Bartus, Henry R

“…As part of a search for novel inhibitors of HIV-1 reverse transcriptase, the acetone extract of the giant African snail, Achatina fulica, was shown to be…”
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A New Dimeric Dihydrochalcone and a New Prenylated Flavone from the Bud Covers of Artocarpus altilis:  Potent Inhibitors of Cathepsin K by PATIL, Ashok D., FREYER, Alan J., KILLMER, Lew, OFFEN, Priscilla, TAYLOR, Paul B., VOTTA, Bartholomew J., JOHNSON, Randall K.

“…A MeOH/CH(2)Cl(2) extract of the bud covers of Artocarpus altilis collected in Micronesia showed activity in a cathepsin K inhibition assay. In addition to the…”
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Brominated Polyacetylenic Acids from the Marine Sponge Xestospongia muta: Inhibitors of HIV Protease by Patil, Ashok D, Kokke, Wilhelmus C, Cochran, Sally, Francis, Terry A, Tomszek, Thaddeus, Westley, John W

“…The EtOAc extract of the sponge Xestospongia muta collected in Colombus Island, Bahamas, yielded eleven straight-chain unsaturated, polyacetylenic, brominated…”
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Halistanol Disulfate B, a Novel Sulfated Sterol from the Sponge Pachastrella sp.:  Inhibitor of Endothelin Converting Enzyme by Patil, Ashok D, Freyer, Alan J, Breen, Ann, Carte, Brad, Johnson, Randall K

“…As part of a search for novel inhibitors of endothelin converting enzyme (ECE), the MeOH extract of a South African sponge, Pachastrella sp., was shown to be…”
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Plakortides, Novel Cyclic Peroxides from the Sponge Plakortis halichondrioides: Activators of Cardiac SR-CA2+-Pumping ATPase by Patil, Ashok D, Freyer, Alan J, Carte, Brad, Johnson, Randall K, Lahouratate, Philippe

“…As part of a search for novel activators of Ca2+ pumping activity of cardiac SR- (sarcoplasmic reticulum), the EtOAc extract of the Jamaican sponge Plakortis…”
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A Screen for Inhibitors of DNA Recombination: Identification of Two New Spirostanol Glycosides from Chamaedorea linearis by Patil, Ashok D, Baures, Paul W, Eggleston, Drake S, Faucette, Leo, Hemling, Mark E, Westley, John W, Johnson, Randall K

“…Two new glycosides have been isolated from the MeOH extract of the stem wood and stem bark of an Ecuadorian plant Chamaedorea linearis, and their structures…”
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Haploscleridamine, a Novel Tryptamine-Derived Alkaloid from a Sponge of the Order Haplosclerida:  An Inhibitor of Cathepsin K by Patil, Ashok D, Freyer, Alan J, Carte, Brad, Taylor, Paul B, Johnson, Randall K, Faulkner, D. John

“…As part of a search for novel inhibitors of cathepsin K, the MeOH extract of a Micronesian sponge of the order Haplosclerida was shown to be active…”
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Three New Pseudodistomins, Piperidine Alkaloids from the Ascidian Pseudodistoma megalarva by Freyer, Alan J, Patil, Ashok D, Killmer, Lew, Troupe, Nelson, Mentzer, Mary, Carte, Brad, Faucette, Leo, Johnson, Randall K

“…Bioassay-guided fractionation of the MeOH−CH2Cl2 extract of the Micronesian ascidian Pseudodistoma megalarva yielded three new piperidine alkaloids,…”
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A New Dimeric Dihydrochalcone and a New Prenylated Flavone from the Bud Covers of Artocarpus a ltilis:  Potent Inhibitors of Cathepsin K by Patil, Ashok D, Freyer, Alan J, Killmer, Lew, Offen, Priscilla, Taylor, Paul B, Votta, Bartholomew J, Johnson, Randall K

“…A MeOH/CH2Cl2 extract of the bud covers of Artocarpus altilis collected in Micronesia showed activity in a cathepsin K inhibition assay. In addition to the…”
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Three New Tricyclic Guanidine Alkaloids from the Sponge Batzella sp by Patil, Ashok D, Freyer, Alan J, Offen, Priscilla, Bean, Mark F, Johnson, Randall K

“…During the large-scale isolation of the batzelladines A and B, which are inhibitors of gp120-CD4 binding, we isolated 19 minor guanidine alkaloids. Three new…”
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Two New Nitrogenous Sesquiterpenes from the Sponge Axinyssa aplysinoides by Patil, Ashok D, Freyer, Alan J, Reichwein, Rex, Bean, Mark F, Faucette, Leo, Johnson, Randall K, Haltiwanger, R. Curtis, Eggleston, Drake S

“…Bioassay-guided fractionation of the EtOAc extract of the Palauan sponge Axinyssa aplysinoides yielded two novel alkaloids, 1 and 2. The structure of…”
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Rigidone, a Sesquiterpene o-Quinone from the Gorgonian Pseudopterogorgia rigida by Freyer, Alan J, Patil, Ashok D, Killmer, Lew, Zuber, Gary, Myers, Cecily, Johnson, Randall K

“…As part of a search for novel biologically active compounds in the Macrophage Scavenger Receptor (MSR) assay, the EtOAc extract of a gorgonian coral,…”
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Daleformis, a New Phytoalexin from the Roots of Dalea filiciformis:  An Inhibitor of Endothelin Converting Enzyme by Patil, Ashok D, Freyer, Alan J, Eggleston, Drake S, Haltiwanger, R. Curtis, Tomcowicz, Brian, Breen, Ann, Johnson, Randall K

“…As part of a search for novel inhibitors of endothelin converting enzyme (ECE), the MeOH−CH2Cl2 extract of the roots of Dalea filiciformis was shown to be…”
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Antibacterial Constituents of the Diatom Navicula delognei by Findlay, John A, Patil, Ashok D

“…The novel ester (E)-phytol (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate++ + (1); (6Z,9Z,12Z,15Z)-hexadecatetraenoic acid; (6Z,9Z,12Z,15Z)-octadecatetraenoic acid; and…”
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Batzelladines F−I, Novel Alkaloids from the Sponge Batzella sp.:  Inducers of p56lck-CD4 Dissociation by Patil, Ashok D, Freyer, Alan J, Taylor, Paul B, Carté, Brad, Zuber, Gary, Johnson, Randall K, Faulkner, D. John

“…The sponge Batzella sp. from Jamaica contains four new alkaloids, batzelladines F−I (1-4), that induce the p56lck−CD4 dissociation. Batzelladines F−I were…”
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Novel Acetylenic Acids from the Root Bark of Paramacrolobium caeruleum: Inhibitors of 3-Hydroxy-3-methyl-glutaryl Coenzyme A Reductase by Patil, Ashok D, Chan, James A, Lois-Flamberg, Pearl, Mayer, Ruth J, Westley, John W

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Frondosins, five new sesquiterpene hydroquinone derivatives with novel skeletons from the sponge Dysidea frondosa: Inhibitors of interleukin-8 receptors by Patil, Ashok D., Freyer, Alan J, Killmer, Lew, Offen, Priscilla, Carte, Brad, Jurewicz, Anthony J., Johnson, Randall K.

“…Bioassay-guided fractionation of the EtOAc extract of the sponge Dysidea frondosa collected in Pohnpei yielded five sesquiterpenes, frondosins A - E ( 1–5)…”
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