Search Results - "PATEL, Shutish C"
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Immunohistochemical localization of dopamine receptor subtypes (D1R–D5R) in Alzheimer's disease brain
Published in Brain research (02-02-2007)“…Abstract Among the neurotransmitter abnormalities that have been investigated in Alzheimer's disease (AD), deficits in the cholinergic system have been the…”
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Ligand Binding to Somatostatin Receptors Induces Receptor-Specific Oligomer Formation in Live Cells
Published in Proceedings of the National Academy of Sciences - PNAS (05-03-2002)“…Heptahelical receptors (HHRs) are generally thought to function as monomeric entities. Several HHRs such as somatostatin receptors (SSTRs), however, form homo-…”
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Lovastatin Modulates Increased Cholesterol and Oxysterol Levels and Has a Neuroprotective Effect on Rat Hippocampal Neurons After Kainate Injury
Published in Journal of neuropathology and experimental neurology (01-07-2006)“…This study was carried out to elucidate the effect of a brain-permeable statin (lovastatin) on cholesterol and oxysterol levels of the hippocampus after…”
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Localization of Niemann-Pick C1 Protein in Astrocytes: Implications for Neuronal Degeneration in Niemann-Pick Type C Disease
Published in Proceedings of the National Academy of Sciences - PNAS (16-02-1999)“…Niemann-Pick type C disease (NP-C) is an inherited neurovisceral lipid storage disorder characterized by progressive neurodegeneration. Most cases of NP-C…”
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Differential expression of D2-like dopamine receptors in the kidney of the spontaneously hypertensive rat
Published in Journal of hypertension (01-01-2003)“…OBJECTIVETo compare the expression and cellular distribution of D2-like dopamine receptors in the kidney of the spontaneously hypertensive rat (SHR) and…”
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Receptors for Dopamine and Somatostatin: Formation of Hetero-Oligomers with Enhanced Functional Activity
Published in Science (American Association for the Advancement of Science) (07-04-2000)“…Somatostatin and dopamine are two major neurotransmitter systems that share a number of structural and functional characteristics. Somatostatin receptors and…”
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Apolipoprotein D modulates F2-isoprostane and 7-ketocholesterol formation and has a neuroprotective effect on organotypic hippocampal cultures after kainate-induced excitotoxic injury
Published in Neuroscience letters (22-05-2009)“…Apolipoprotein D (apoD), a member of the lipocalin family of transporter proteins binds a number of small lipophilic molecules including arachidonic acid and…”
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Astrocytes synthesize and secrete the lipophilic ligand carrier apolipoprotein D
Published in Neuroreport (07-03-1995)“…Expression of the lipophilic ligand transporter, apolipoprotein D (apoD) by primary astrocyte cultures derived from neonatal mouse brain was investigated…”
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Expression of somatostatin and somatostatin receptor subtypes in Apolipoprotein D (ApoD) knockout mouse brain: An immunohistochemical analysis
Published in Journal of chemical neuroanatomy (01-09-2009)“…Apolipoprotein D (ApoD) is widely distributed in central and peripheral nervous system. ApoD expression has been shown to increase in several neurodegenerative…”
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Neurodegeneration in Niemann-Pick type C disease mice
Published in Experimental brain research (01-11-2001)“…Niemann-Pick disease type C (NP-C) is an inherited neurodegenerative disorder associated with intracellular cholesterol and glycolipid trafficking defects. Two…”
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Increase in Cholesterol and Cholesterol Oxidation Products, and Role of Cholesterol Oxidation Products in Kainate-induced Neuronal Injury
Published in Brain pathology (Zurich, Switzerland) (01-07-2003)“…Little is known about changes in sterols, in particular cholesterol, and cholesterol oxidation products (COPs) in oxidative injury in neural tissues. We have…”
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Retinol and retinoic acid bind to a surface cleft in bovine β-lactoglobulin: a method of binding site determination using fluorescence resonance energy transfer
Published in Biophysical chemistry (04-08-1998)“…Two potential ligand binding sites in the lipocalin β-lactoglobulin have been postulated for small hydrophobic molecules such as retinol or retinoic acid. An…”
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Expression of the carrier protein apolipoprotein D in the mouse inner ear
Published in Hearing research (01-02-2005)“…The cochlear portion of the inner ear converts movements produced by sound waves into electrical impulses. Transcripts enriched in the cochlea are likely to…”
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Apolipoprotein D modulates F 2-isoprostane and 7-ketocholesterol formation and has a neuroprotective effect on organotypic hippocampal cultures after kainate-induced excitotoxic injury
Published in Neuroscience letters (22-05-2009)“…Apolipoprotein D (apoD), a member of the lipocalin family of transporter proteins binds a number of small lipophilic molecules including arachidonic acid and…”
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25-Hydroxycholesterol induces reorganization of lysosomes in normal but not Niemann-Pick disease type C astrocytes
Published in Neuroreport (27-10-1994)“…25-hydroxycholesterol (25-OHC), an oxysterol that potently regulates cellular cholesterol metabolism, induced formation of novel fibrillar structures in normal…”
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Subtype-selective expression of the five somatostatin receptors (hSSTR1-5) in human pancreatic islet cells: a quantitative double-label immunohistochemical analysis
Published in Diabetes (New York, N.Y.) (01-01-1999)“…Subtype-selective expression of the five somatostatin receptors (hSSTR1-5) in human pancreatic islet cells: a quantitative double-label immunohistochemical…”
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Apolipoprotein D modulates F sub(2)-isoprostane and 7-ketocholesterol formation and has a neuroprotective effect on organotypic hippocampal cultures after kainate-induced excitotoxic injury
Published in Neuroscience letters (01-05-2009)“…Apolipoprotein D (apoD), a member of the lipocalin family of transporter proteins binds a number of small lipophilic molecules including arachidonic acid and…”
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Apolipoprotein D in the Niemann-Pick type C disease mouse brain: an ultrastructural immunocytochemical analysis
Published in Journal of neurocytology (01-02-2002)“…Enhanced apoD gene expression and abnormally high levels of apoD protein accumulation in the brain have been previously documented as features of the…”
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Cellular Cholesterol Storage in the Niemann‐Pick Disease Type C Mouse Is Associated with Increased Expression and Defective Processing of Apolipoprotein D
Published in Journal of neurochemistry (01-01-1998)“…: Apolipoprotein D (apoD), a member of the lipocalin superfamily of ligand transporters, has been implicated in the transport of several small hydrophobic…”
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