Search Results - "PATEL, Chhagan N"

A Review on DNA Repair Inhibition by PARP Inhibitors in Cancer Therapy by Shah, Ashish P, Patel, Chhagan N, Sureja, Dipen K, Sanghavi, Kirtan P

“…The DNA repair process protects the cells from DNA damaging agent by multiple pathways. Majority of the cancer therapy cause DNA damage which leads to…”
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A rapid and specific approach for direct measurement of donepezil concentration in human plasma by LC-MS/MS employing solid-phase extraction by Shah, Hiten J., Kundlik, Mohan L., Pandya, Ankit, Prajapati, Shivkumar, Subbaiah, Gunta, Patel, Chhagan N., Patel, Dasharath M., Suhagiya, Bhanu N.

“…A selective, rapid and simple liquid chromatography–tandem mass spectrometry (LC‐MS/MS) method is described for assay of donepezil in human plasma using…”
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In vitro-in vivo correlation of modified release dosage form of lamotrigine by Shah, Hiten J., Subbaiah, Gunta, Patel, Dasharath M., Patel, Chhagan N.

“…The plasma concentration profile of lamotrigine was predicted from the dissolution test data of the modified release 100 mg lamotrigine tablet by applying the…”
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Development of a Novel Floating In-situ Gelling System for Stomach Specific Drug Delivery of the Narrow Absorption Window Drug Baclofen by R Jivani, Rishad, N Patel, Chhagan, M Patel, Dashrath, P Jivani, Nurudin

“…The present study deals with development of a floating in-situ gel of the narrow absorption window drug baclofen. Sodium alginate-based in-situ gelling systems…”
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The genotoxic and cytotoxic effects of nimesulide in the mouse bone marrow by Tripathi, Rina, Tripathi, Pankaj, Pancholi, Shyam S., Patel, Chhagan N.

“…Abstract Genotoxicity of nimesulide (NM) was evaluated by employing bone marrow (BM) chromosomal aberration (CA) and micronucleus assays in Swiss albino mice…”
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Formulation and evaluation of fast dissolving tablet containing domperidone ternary solid dispersion by Patel, Dasharath M, Patel, Sweeti P, Patel, Chhagan N

“…Fast dissolving tablet containing domperidone ternary solid dispersion was developed to improve the dissolution of drug and stability of solid dispersion…”
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Preparation and characterization of superporous hydrogel based on different polymers by Chavda, Hitesh V, Patel, Rupal D, Modhia, Ishan P, Patel, Chhagan N

“…Superporous hydrogel (SPH) swells very rapidly in a shorter period of time to an equilibrium size and contains highly porous structure. The synthesis of SPH of…”
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Rapid determination of losartan and losartan acid in human plasma by multiplexed LC-MS/MS by Shah, Hiten J, Kundlik, Mohan L, Patel, Nitesh K, Subbaiah, Gunta, Patel, Dasharath M, Suhagia, Bhanubhai N, Patel, Chhagan N

“…A rapid LC-MS/MS method has been developed and validated for the determination of losartan (LOS) and its metabolite losartan acid (LA) (EXP-3174) in human…”
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Design and evaluation of colon targeted modified pulsincap delivery of 5-fluorouracil according to circadian rhythm by Patel, Dasharath M, Jani, Rushiraj H, Patel, Chhagan N

“…A modified pulsincap dosage form of 5-fluorouracil was developed to target drug to colorectal carcinoma according to daily oscillations of rate-limiting…”
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Quantification of Paroxetine in Human Plasma by Liquid Chromatography Coupled with Electrospray Ionization Tandem Mass Spectrometry by SHAH, Hiten J, KUNDLIK, Mohan L, KAKAD, Abhijit, PATEL, Nitesh K, PANDYA, Ankit, KHATRI, Vanita, PRAJAPATI, Shivkumat, SUBBAIAH, Gunta, PATEL, Chhagan N

“…A rapid LC coupled with electrospray ionization (ESI) MS/MS method was developed and validated for the quantification of paroxetine in heparinized human…”
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Rapid Quantification of Lamotrigine in Human Plasma by Two LC Systems Connected with Tandem MS by Shah, Hiten J., Subbaiah, Gunta, Patel, Dasharath M., Suhagia, Bhanubhai N., Patel, Chhagan N.

“…A rapid and sensitive liquid chromatography-tandem mass spectrometry (LC.MS.MS) method has been developed and validated for the determination of lamotrigine in…”
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Formulation and evaluation of floating matrix tablet of stavudine by Prajapati, Pankaj H, Nakum, Vijay V, Patel, Chhagan N

“…The purpose of the study was to prolong the gastric residence time of stavudine by designing its floating tablets and to study the influence of different…”
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Formulation and evaluation of mixed matrix gastro-retentive drug delivery for famotidine by Patel, Dasharath M, Patel, Mehul J, Patel, Ankit N, Patel, Chhagan N

“…Present investigation describes an influence of ratio of Gelucire 43/01(hydrophobic) to hydroxypropyl methylcellulose K4M (HPMC K4M) (hydrophilic) and…”
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Development and validation of a method for simultaneous estimation of ofloxacin and ornidazole in different dissolution media by Patel, Dasharath M., Soneji, Jignesh A., Patel, Parth B., Patel, Chhagan N.

“…Introduction: Ofloxacin and ornidazole in a combined tablet dosage form is available in the market. This combination has gained increasing acceptance in…”
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Development and validation of spectrophotometric method for simultaneous estimation of paracetamol and lornoxicam in different dissolution media by Patel, Dasharath M., Sardhara, Bhavesh M., Thumbadiya, Diglesh H., Patel, Chhagan N.

“…Background: Paracetamol and lornoxicam in combined tablet dosage form are available in the market. This combination is used to treat inflammatory diseases of…”
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Stability-indicating high-performance thin-layer chromatographic method for analysis of itraconazole in bulk drug and in pharmaceutical dosage form by Parikh, Shalin K., Dave, Jayant B., Patel, Chhagan N., Ramalingan, Badmanaban

“…Background: A new, simple, selective, precise, and stability-indicating high-performance thin-layer chromatographic method has been established for analysis of…”
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Formulation and Evaluation of Floating Oral In Situ Gelling System of Amoxicillin by Patel, Dasharath M., Patel, Divyesh K., Patel, Chhaganbhai N.

“…Purpose. Effective Helicobacter pylori eradication requires delivery of the antibiotic locally in the stomach. High dose of amoxicillin (750 to 1000 mg) is…”
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Formulation and Evaluation of Controlled-Release Tablet of Zolpidem Tartrate by Melt Granulation Technique by Prajapati, Shailesh T., Patel, Amit N., Patel, Chhaganbhai N.

“…The present investigation describes the influence of the concentration of PEG 6000 as a melt binder and ratio of HPMC K4M : PVP on Zolpidem tartrate…”
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Formulation and Evaluation of Transdermal Patch of Repaglinide by Prajapati, Shailesh T., Patel, Charmi G., Patel, Chhaganbhai N.

“…Repaglinide has the half life of 1 hour, and bioavailability in the body is 56% due to first-pass metabolism. The total daily dose of Repaglinide is 16 mg…”
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Formulation and optimisation of raft-forming chewable tablets containing H 2 antagonist by Prajapati, Shailesh, Mehta, Anant, Modhia, Ishan, Patel, Chhagan

“…Purpose: The purpose of this research work was to formulate raft-forming chewable tablets of H 2 antagonist (Famotidine) using a raft-forming agent along with…”
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