Search Results - "PASTORE, Anna"

Protein glutathionylation in cardiovascular diseases by Pastore, Anna, Piemonte, Fiorella

“…The perturbation of thiol-disulfide homeostasis is an important consequence of many diseases, with redox signals implicated in several physio-pathological…”
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A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function by Lam, Michael T, Coppola, Simona, Krumbach, Oliver H F, Prencipe, Giusi, Insalaco, Antonella, Cifaldi, Cristina, Brigida, Immacolata, Zara, Erika, Scala, Serena, Di Cesare, Silvia, Martinelli, Simone, Di Rocco, Martina, Pascarella, Antonia, Niceta, Marcello, Pantaleoni, Francesca, Ciolfi, Andrea, Netter, Petra, Carisey, Alexandre F, Diehl, Michael, Akbarzadeh, Mohammad, Conti, Francesca, Merli, Pietro, Pastore, Anna, Levi Mortera, Stefano, Camerini, Serena, Farina, Luciapia, Buchholzer, Marcel, Pannone, Luca, Cao, Tram N, Coban-Akdemir, Zeynep H, Jhangiani, Shalini N, Muzny, Donna M, Gibbs, Richard A, Basso-Ricci, Luca, Chiriaco, Maria, Dvorsky, Radovan, Putignani, Lorenza, Carsetti, Rita, Janning, Petra, Stray-Pedersen, Asbjorg, Erichsen, Hans Christian, Horne, AnnaCarin, Bryceson, Yenan T, Torralba-Raga, Lamberto, Ramme, Kim, Rosti, Vittorio, Bracaglia, Claudia, Messia, Virginia, Palma, Paolo, Finocchi, Andrea, Locatelli, Franco, Chinn, Ivan K, Lupski, James R, Mace, Emily M, Cancrini, Caterina, Aiuti, Alessandro, Ahmadian, Mohammad R, Orange, Jordan S, De Benedetti, Fabrizio, Tartaglia, Marco

“…Hemophagocytic lymphohistiocytosis (HLH) is characterized by immune dysregulation due to inadequate restraint of overactivated immune cells and is associated…”
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Contribution of vitamin D3 and thiols status to the outcome of COVID-19 disease in Italian pediatric and adult patients by D’Alessandro, Annamaria, Ciavardelli, Domenico, Pastore, Anna, Lupisella, Santina, Cristofaro, Rosa Carmela, Di Felice, Giovina, Salierno, Roberta, Infante, Marco, De Stefano, Alberto, Onetti Muda, Andrea, Morello, Maria, Porzio, Ottavia

“…The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV-2), was declared a global pandemic by the World…”
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Nrf2-Inducers Counteract Neurodegeneration in Frataxin-Silenced Motor Neurons: Disclosing New Therapeutic Targets for Friedreich's Ataxia by Petrillo, Sara, Piermarini, Emanuela, Pastore, Anna, Vasco, Gessica, Schirinzi, Tommaso, Carrozzo, Rosalba, Bertini, Enrico, Piemonte, Fiorella

“…Oxidative stress is actively involved in Friedreich's Ataxia (FA), thus pharmacological targeting of the antioxidant machinery may have therapeutic value…”
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Plasma levels of homocysteine and cysteine increased in pediatric NAFLD and strongly correlated with severity of liver damage by Pastore, Anna, Alisi, Anna, di Giovamberardino, Gianna, Crudele, Annalisa, Ceccarelli, Sara, Panera, Nadia, Dionisi-Vici, Carlo, Nobili, Valerio

“…Non-alcoholic fatty liver disease (NAFLD) is a spectrum of metabolic abnormalities ranging from simple triglyceride accumulation in the hepatocytes to hepatic…”
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Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells by Rega, Laura R, Polishchuk, Elena, Montefusco, Sandro, Napolitano, Gennaro, Tozzi, Giulia, Zhang, Jinzhong, Bellomo, Francesco, Taranta, Anna, Pastore, Anna, Polishchuk, Roman, Piemonte, Fiorella, Medina, Diego L, Catz, Sergio D, Ballabio, Andrea, Emma, Francesco

“…Nephropathic cystinosis is a rare autosomal recessive lysosomal storage disease characterized by accumulation of cystine into lysosomes secondary to mutations…”
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Almost Kenmotsu Manifolds and Nullity Distributions by Dileo, Giulia, Pastore, Anna Maria

“… We characterize almost contact metric manifolds which are CR -integrable almost Kenmotsu, through the existence of a suitable linear connection. We classify…”
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Analysis of glutathione: implication in redox and detoxification by Pastore, Anna, Federici, Giorgio, Bertini, Enrico, Piemonte, Fiorella

“…Background: Glutathione is a ubiquitous thiol-containing tripeptide, which plays a central role in cell biology. It is implicated in the cellular defence…”
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Pitfalls in the quantitative imaging of glutathione in living cells by Cossetti, Cristina, Di Giovamberardino, Gianna, Rota, Rossella, Pastore, Anna

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EPI-743 reverses the progression of the pediatric mitochondrial disease—Genetically defined Leigh Syndrome by Martinelli, Diego, Catteruccia, Michela, Piemonte, Fiorella, Pastore, Anna, Tozzi, Giulia, Dionisi-Vici, Carlo, Pontrelli, Giuseppe, Corsetti, Tiziana, Livadiotti, Susanna, Kheifets, Viktoria, Hinman, Andrew, Shrader, William D., Thoolen, Martin, Klein, Matthew B., Bertini, Enrico, Miller, Guy

“…Genetically defined Leigh syndrome is a rare, fatal inherited neurodegenerative disorder that predominantly affects children. No treatment is available…”
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Drug Repurposing in Rare Diseases: An Integrative Study of Drug Screening and Transcriptomic Analysis in Nephropathic Cystinosis by Bellomo, Francesco, De Leo, Ester, Taranta, Anna, Giaquinto, Laura, Di Giovamberardino, Gianna, Montefusco, Sandro, Rega, Laura Rita, Pastore, Anna, Medina, Diego Luis, Di Bernardo, Diego, De Matteis, Maria Antonietta, Emma, Francesco

“…Diagnosis and cure for rare diseases represent a great challenge for the scientific community who often comes up against the complexity and heterogeneity of…”
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Author Correction: Contribution of vitamin D3 and thiols status to the outcome of COVID-19 disease in Italian pediatric and adult patients by D’Alessandro, Annamaria, Ciavardelli, Domenico, Pastore, Anna, Lupisella, Santina, Cristofaro, Rosa Carmela, Di Felice, Giovina, Salierno, Roberta, Infante, Marco, De Stefano, Alberto, Onetti Muda, Andrea, Morello, Maria, Porzio, Ottavia

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Endo-lysosomal dysfunction in human proximal tubular epithelial cells deficient for lysosomal cystine transporter cystinosin by Ivanova, Ekaterina A, De Leo, Maria Giovanna, Van Den Heuvel, Lambertus, Pastore, Anna, Dijkman, Henry, De Matteis, Maria Antonietta, Levtchenko, Elena N

“…Nephropathic cystinosis is a lysosomal storage disorder caused by mutations in the CTNS gene encoding cystine transporter cystinosin that results in…”
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Study of the Association between Thiols and Oxidative Stress Markers in Children with Obesity by D’Alessandro, Annamaria, Di Felice, Giovina, Manco, Melania, Pastore, Anna, Pezzi, Simona, Mariani, Michela, Fintini, Danilo, Onetti Muda, Andrea, Porzio, Ottavia

“…Obesity has reached epidemic proportions, and the World Health Organization defined childhood overweight and obesity as a noncommunicable disease that…”
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A new simple and rapid LC–ESI-MS/MS method for quantification of plasma oxysterols as dimethylaminobutyrate esters. Its successful use for the diagnosis of Niemann–Pick type C disease by Boenzi, Sara, Deodato, Federica, Taurisano, Roberta, Martinelli, Diego, Verrigni, Daniela, Carrozzo, Rosalba, Bertini, Enrico, Pastore, Anna, Dionisi-Vici, Carlo, Johnson, David W.

“…Two oxysterols, cholestan-3β,5α,6β-triol (C-triol) and 7-ketocholesterol (7-KC), have been recently proposed as diagnostic markers of Niemann–Pick type C…”
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Plasminogen Activator Inhibitor-1 and Vitamin D Association in the Overweight and Obese Pediatric Population by Di Felice, Giovina, D’Alessandro, Annamaria, Pastore, Anna, Mariani, Michela, Fintini, Danilo, Aureli, Alessia, Pezzi, Simona, Montemari, Anna Lisa, Rocco, Beatrice Barbara, Borseti, Andrea, Onetti Muda, Andrea, Manco, Melania, Porzio, Ottavia

“…Background: Childhood overweight and obesity have been described by the World Health Organization as noncommunicable diseases and among the greatest public…”
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Focal adhesion kinase inhibitor TAE226 combined with Sorafenib slows down hepatocellular carcinoma by multiple epigenetic effects by Romito, Ilaria, Porru, Manuela, Braghini, Maria Rita, Pompili, Luca, Panera, Nadia, Crudele, Annalisa, Gnani, Daniela, De Stefanis, Cristiano, Scarsella, Marco, Pomella, Silvia, Levi Mortera, Stefano, de Billy, Emmanuel, Conti, Adrian Libenzio, Marzano, Valeria, Putignani, Lorenza, Vinciguerra, Manlio, Balsano, Clara, Pastore, Anna, Rota, Rossella, Tartaglia, Marco, Leonetti, Carlo, Alisi, Anna

“…Hepatocellular carcinoma (HCC) is one of the most common and lethal malignant tumours worldwide. Sorafenib (SOR) is one of the most effective single-drug…”
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Systemic Redox Biomarkers in Neurodegenerative Diseases by Pastore, Anna, Petrillo, Sara, Piermarini, Emanuela, Piemonte, Fiorella

“…Neurodegenerative diseases are characterized by a gradual and selective loss of neurons. ROS overload has been proved to occur early in this heterogeneous…”
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Emodin prevents intrahepatic fat accumulation, inflammation and redox status imbalance during diet-induced hepatosteatosis in rats by Alisi, Anna, Pastore, Anna, Ceccarelli, Sara, Panera, Nadia, Gnani, Daniela, Bruscalupi, Giovannella, Massimi, Mara, Tozzi, Giulia, Piemonte, Fiorella, Nobili, Valerio

“…High-fat and/or high-carbohydrate diets may predispose to several metabolic disturbances including liver fatty infiltration (hepatosteatosis) or be associated…”
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Correction to: Focal adhesion kinase inhibitor TAE226 combined with Sorafenib slows down hepatocellular carcinoma by multiple epigenetic effects by Romito, Ilaria, Porru, Manuela, Braghini, Maria Rita, Pompili, Luca, Panera, Nadia, Crudele, Annalisa, Gnani, Daniela, De Stefanis, Cristiano, Scarsella, Marco, Pomella, Silvia, Mortera, Stefano Levi, de Billy, Emmanuel, Conti, Adrian Libenzio, Marzano, Valeria, Putignani, Lorenza, Vinciguerra, Manlio, Balsano, Clara, Pastore, Anna, Rota, Rossella, Tartaglia, Marco, Leonetti, Carlo, Alisi, Anna

“…An amendment to this paper has been published and can be accessed via the original article…”
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