Search Results - "PASSERINI, L"

Immunoregulatory cell therapy with lentiviral-mediated FOXP3 converted CD4+ T cells into Treg cells: towards the proof-of-concept application in IPEX syndrome by Sato, Y, Passerini, L, Roncarolo, M, Bacchetta, R

“…Background & AimFOXP3 is an essential transcription factor for the regulatory T cell (Treg) function and therefore is a key regulator for the tolerance…”
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CRISPR-based gene editing enables FOXP3 gene repair in IPEX patient cells by Goodwin, M, Lee, E, Lakshmanan, U, Shipp, S, Froessl, L, Barzaghi, F, Passerini, L, Narula, M, Sheikali, A, Lee, C M, Bao, G, Bauer, C S, Miller, H K, Garcia-Lloret, M, Butte, M J, Bertaina, A, Shah, A, Pavel-Dinu, M, Hendel, A, Porteus, M, Roncarolo, M G, Bacchetta, R

“…The prototypical genetic autoimmune disease is immune dysregulation polyendocrinopathy enteropathy X-linked (IPEX) syndrome, a severe pediatric disease with…”
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Ectopic FOXP3 Expression Preserves Primitive Features Of Human Hematopoietic Stem Cells While Impairing Functional T Cell Differentiation by Santoni de Sio, F. R., Passerini, L., Valente, M. M., Russo, F., Naldini, L., Roncarolo, M. G., Bacchetta, R.

“…FOXP3 is the transcription factor ruling regulatory T cell function and maintenance of peripheral immune tolerance, and mutations in its coding gene causes…”
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Carcinogenicity of the aromatic amines: from structure–activity relationships to mechanisms of action and risk assessment by Benigni, Romualdo, Passerini, Laura

“…Aromatic amines represent one of the most important classes of industrial and environmental chemicals: many of them have been reported to be powerful…”
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Demethylation analysis of the FOXP3 locus shows quantitative defects of regulatory T cells in IPEX-like syndrome by Barzaghi, F, Passerini, L, Gambineri, E, Ciullini Mannurita, S, Cornu, T, Kang, E.S, Choe, Y.H, Cancrini, C, Corrente, S, Ciccocioppo, R, Cecconi, M, Zuin, G, Discepolo, V, Sartirana, C, Schmidtko, J, Ikinciogullari, A, Ambrosi, A, Roncarolo, M.G, Olek, S, Bacchetta, R

“…Abstract Immune dysregulation, Polyendocrinopathy, Enteropathy X-linked (IPEX) syndrome is a unique example of primary immunodeficiency characterized by…”
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HIV-1 mediated insertional activation of STAT5B and BACH2 promotes the formation of a viral reservoir in T regulatory cells by D. Cesana, F. Santoni de Sio, L. Rudilosso, P. Gallina, A. Calabria, E. Bruzzesi, L. Passerini, S. Nozza, E. Vicenzi, G. Poli, S. Gregori, G. Tambussi, E. Montini

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HIV-1 mediated insertional activation of STAT5B promotes the formation of a viral reservoir in T regulatory cells by D. Cesana, F.R. Santoni de Sio, L. Rudilosso, P. Gallina, A. Calabria, L. Passerini, S. Nozza, E. Vicenzi, G. Poli, G. Tambussi, E. Montini

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Similar binding to glutamate receptors by Rasmussen and partial epilepsy patients' sera by BERNASCONI, P, CIPELLETTI, B, PASSERINI, L, GRANATA, T, ANTOZZI, C, MANTEGAZZA, R, SPREAFICO, R

“…Immunoreactivity of sera from patients with Rasmussen encephalitis (RE) and patients with partial epilepsy (PE) was analyzed by immunohistoblot on rat brain…”
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Abdominal distension after colonic lactulose fermentation recorded by a new extensometer by Basilisco, G., Marino, B., Passerini, L., Ogliari, C.

“…Colonic lactulose fermentation induces bloating, but whether it also causes abdominal distension is not known. The aim of this study was to assess the effect…”
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Hematopoietic Stem- and Progenitor-Cell Gene Therapy for Hurler Syndrome by Gentner, Bernhard, Tucci, Francesca, Galimberti, Stefania, Fumagalli, Francesca, De Pellegrin, Maurizio, Silvani, Paolo, Camesasca, Chiara, Pontesilli, Silvia, Darin, Silvia, Ciotti, Francesca, Sarzana, Marina, Consiglieri, Giulia, Filisetti, Chiara, Forni, Giulia, Passerini, Laura, Tomasoni, Daniela, Cesana, Daniela, Calabria, Andrea, Spinozzi, Giulio, Cicalese, Maria-Pia, Calbi, Valeria, Migliavacca, Maddalena, Barzaghi, Federica, Ferrua, Francesca, Gallo, Vera, Miglietta, Simona, Zonari, Erika, Cheruku, Patali S, Forni, Claudia, Facchini, Marcella, Corti, Ambra, Gabaldo, Michela, Zancan, Stefano, Gasperini, Serena, Rovelli, Attilio, Boelens, Jaap-Jan, Jones, Simon A, Wynn, Robert, Baldoli, Cristina, Montini, Eugenio, Gregori, Silvia, Ciceri, Fabio, Valsecchi, Maria G, la Marca, Giancarlo, Parini, Rossella, Naldini, Luigi, Aiuti, Alessandro, Bernardo, Maria-Ester

“…Eight patients with Hurler syndrome who lacked suitable allogeneic donors received autologous hematopoietic stem and progenitor cells transduced ex vivo with…”
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Biofilms on indwelling vascular catheters by Passerini, L, Lam, K, Costerton, J W, King, E G

“…Some bacteria have a natural tendency to adhere to available surfaces and to form biofilms. Biofilms have been demonstrated on right heart flow-directed…”
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Infection with fatal outcome after endovascular metallic stent placement by Therasse, E, Soulez, G, Cartier, P, Passerini, L, Roy, P, Bruneau, L, Gaboury, L

“…The authors describe a case in which infection developed in a patient after placement of a metallic endoprosthesis in the iliac artery. The patient died of…”
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QSAR models for discriminating between mutagenic and nonmutagenic aromatic and heteroaromatic amines by Benigni, Romualdo, Passerini, Laura, Gallo, Grazia, Giorgi, Fabrizio, Cotta-Ramusino, Marina

“…In a previous article, we demonstrated that the structure–activity relationship model for the mutagenic potency of aromatic amines is different from that for…”
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Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production by Allan, Sarah E., Crome, Sarah Q., Crellin, Natasha K., Passerini, Laura, Steiner, Theodore S., Bacchetta, Rosa, Roncarolo, Maria G., Levings, Megan K.

“…Forkhead box P3 (FOXP3) is currently thought to be the most specific marker for naturally occurring CD4+CD25+ T regulatory cells (nTregs). In mice, expression…”
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The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs by Allan, Sarah E, Passerini, Laura, Bacchetta, Rosa, Crellin, Natasha, Dai, Minyue, Orban, Paul C, Ziegler, Steven F, Roncarolo, Maria Grazia, Levings, Megan K

“…Little is known about the molecules that control the development and function of CD4+ CD25+ Tregs. Recently, it was shown that the transcription factor FOXP3…”
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A Passion for Memory by Passerini, Luisa

“…Moving through personal, intellectual and political autobiography this brief article traces the author's relationship with stories, memory and history. Her…”
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A Randomized, Controlled Trial of the Use of Pulmonary-Artery Catheters in High-Risk Surgical Patients by Sandham, James Dean, Hull, Russell Douglas, Brant, Rollin Frederick, Knox, Linda, Pineo, Graham Frederick, Doig, Christopher J, Laporta, Denny P, Viner, Sidney, Passerini, Louise, Devitt, Hugh, Kirby, Ann, Jacka, Michael

“…In this large trial, elderly, high-risk patients were randomly assigned before surgery to goal-directed therapy guided by a pulmonary-artery catheter or to…”
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An allosteric-feedback mechanism for protein-assisted group I intron splicing by Caprara, Mark G, Chatterjee, Piyali, Solem, Amanda, Brady-Passerini, Kristina L, Kaspar, Benjamin J

“…The I-AniI maturase facilitates self-splicing of a mitochondrial group I intron in Aspergillus nidulans. Binding occurs in at least two steps: first, a…”
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Brain hemorrhage associated with methanol poisoning by Phang, P T, Passerini, L, Mielke, B, Berendt, R, King, E G

“…We recently treated seven patients who were victims of accidental methanol intoxication. Five of the seven patients died within 72 h of hospital admission. The…”
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Increased Toll-Like Receptor 4 Expression in Thymus of Myasthenic Patients with Thymitis and Thymic Involution by Bernasconi, Pia, Barberis, Massimo, Baggi, Fulvio, Passerini, Laura, Cannone, Maria, Arnoldi, Elisa, Novellino, Lorenzo, Cornelio, Ferdinando, Mantegazza, Renato

“…Thymic abnormalities are present in ∼80% of myasthenia gravis (MG) patients, and the thymus seems to be the main site of autosensitization to the acetylcholine…”
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