Search Results - "PASSAGNE, Isabelle"
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Cytotoxicity and oxidative stress induced by different metallic nanoparticles on human kidney cells
Published in Particle and fibre toxicology (03-03-2011)“…Some manufactured nanoparticles are metal-based and have a wide variety of applications in electronic, engineering and medicine. Until now, many studies have…”
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Implication of oxidative stress in size-dependent toxicity of silica nanoparticles in kidney cells
Published in Toxicology (Amsterdam) (28-09-2012)“…Abstract Silica nanoparticles (nano-SiO2 ) are one of the most popular nanomaterials used in industrial manufacturing, synthesis, engineering and medicine…”
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Comparative cytotoxicity of cadmium forms (CdCl 2 , CdO, CdS micro- and nanoparticles) in renal cells
Published in Toxicology research (Cambridge) (2014)“…Cadmium (Cd) is a potent selective toxicant that preferentially accumulates in the kidneys where it is known to induce cellular injury. The cellular mechanisms…”
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Glutathione S-transferase M1 and multidrug resistance protein 1 act in synergy to protect melanoma cells from vincristine effects
Published in Molecular pharmacology (01-04-2004)“…Previous studies have shown that glutathione S-transferases (GSTs) can operate in synergy with efflux transporters, multi-drug resistance proteins (MRPs), to…”
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Cytotoxicity, DNA damage, and apoptosis induced by new fotemustine analogs on human melanoma cells in relation to O6-methylguanine DNA-methyltransferase expression
Published in The Journal of pharmacology and experimental therapeutics (01-11-2003)“…Fotemustine is a third generation chloroethylnitrosourea that has demonstrated significant antitumoral effects in malignant melanoma. However, its use is…”
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Identification of Metallothionein Subisoforms in HPLC Using Accurate Mass and Online Sequencing by Electrospray Hybrid Linear Ion Trap-Orbital Ion Trap Mass Spectrometry
Published in Analytical chemistry (Washington) (15-08-2010)“…A comprehensive approach to the characterization of metallothionein (MT) isoforms based on microbore HPLC with multimodal detection was developed. MTs were…”
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Cytotoxic effects and cellular oxidative mechanisms of metallic nanoparticles on renal tubular cells: impact of particle solubility
Published in Toxicology research (Cambridge) (01-01-2015)“…Many uncertainties remain regarding the potential toxic effect of nanoparticles (NPs). NPs can cross biological barriers, be carried in blood to kidneys, and…”
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O(6)-methylguanine DNA-methyltransferase (MGMT) overexpression in melanoma cells induces resistance to nitrosoureas and temozolomide but sensitizes to mitomycin C
Published in Toxicology and applied pharmacology (01-03-2006)“…Alkylating agents play an important role in the chemotherapy of malignant melanomas. The activity of alkylating agents depends on their capacity to form alkyl…”
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Comparative cytotoxicity of cadmium forms (CdCl sub(2), CdO, CdS micro- and nanoparticles) in renal cells
Published in Toxicology research (Cambridge) (01-12-2013)“…Cadmium (Cd) is a potent selective toxicant that preferentially accumulates in the kidneys where it is known to induce cellular injury. The cellular mechanisms…”
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O 6-methylguanine DNA-methyltransferase (MGMT) overexpression in melanoma cells induces resistance to nitrosoureas and temozolomide but sensitizes to mitomycin C
Published in Toxicology and applied pharmacology (01-03-2006)“…Alkylating agents play an important role in the chemotherapy of malignant melanomas. The activity of alkylating agents depends on their capacity to form alkyl…”
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In vitro effects of nanoparticles on renal glomerular mesangial and tubular epithelial cells
Published in Toxicology letters (01-10-2007)Get full text
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Glutathione synthesis inhibitor increases cadmium-induced oxidative stress and cytotoxicity in glomerular kidney cells
Published in Toxicology letters (01-10-2007)Get full text
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Cytotoxic and apoptotic effects of bortezomib and gefitinib compared to alkylating agents on human glioblastoma cells
Published in Journal of experimental therapeutics & oncology (2008)“…Glioblastoma is a malignant astrocytic tumor with a median survival of about 12 months for which new therapeutic strategies are required. We therefore examined…”
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ICP/OES Application for Assessing Cadmium Uptake (or Toxicity) in Glomerular Cells: Influence of Extracellular Calcium
Published in Journal of Toxicology and Environmental Health, Part A (01-05-2007)“…The risks of metals for health are highlighted by their chemical stability and their persistence in the environment. Chronic exposure to low cadmium (Cd)…”
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Anticancer drugs exert differential apoptotic and cytotoxic effects on glioblastoma primary cultures with various EGFR and bcl-2 profiles
Published in Journal of experimental therapeutics & oncology (2009)“…The aim of this study was to determine the apoptotic and cytotoxic effects induced on glioblastoma cells by various anticancer agents that possess different…”
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Synthesis and biological evaluation of Fotemustine analogues on human melanoma cell lines
Published in European journal of medicinal chemistry (01-03-2003)“…Two new analogues of Fotemustine have been synthesized and tested on two melanoma cell lines. Compounds 4 and 8 proved to be more potent than the reference…”
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Synthesis and biological evaluation of Fotemustine analogues on human melanoma cell lines
Published in European journal of medicinal chemistry (01-03-2003)Get full text
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